Gut microbial beta-glucuronidase and glycerol/diol dehydratase activity contribute to dietary heterocyclic amine biotransformation.
Autorzy:
Zhang J; Department of Health Sciences and Technology, ETH Zürich, Zürich, Switzerland.; Present Address: Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. Lacroix C; Department of Health Sciences and Technology, ETH Zürich, Zürich, Switzerland. Wortmann E; Department of Health Sciences and Technology, ETH Zürich, Zürich, Switzerland. Ruscheweyh HJ; Department of Biology, ETH Zürich, Zürich, Switzerland. Sunagawa S; Department of Biology, ETH Zürich, Zürich, Switzerland. SturlaSJ; Department of Health Sciences and Technology, ETH Zürich, Zürich, Switzerland. Schwab C; Department of Health Sciences and Technology, ETH Zürich, Zürich, Switzerland. .
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Źródło:
BMC microbiology [BMC Microbiol] 2019 May 16; Vol. 19 (1), pp. 99. Date of Electronic Publication: 2019 May 16.
Iron phosphate nanoparticles for food fortification: Biological effects in rats and human cell lines.
Autorzy:
von Moos LM; a Department of Health Sciences and Technology , ETH Zürich , Switzerland. Schneider M; a Department of Health Sciences and Technology , ETH Zürich , Switzerland. Hilty FM; a Department of Health Sciences and Technology , ETH Zürich , Switzerland. Hilbe M; b Institute of Veterinary Pathology, University of Zurich-Vetsuisse , Switzerland. Arnold M; a Department of Health Sciences and Technology , ETH Zürich , Switzerland. Ziegler N; a Department of Health Sciences and Technology , ETH Zürich , Switzerland. Mato DS; a Department of Health Sciences and Technology , ETH Zürich , Switzerland. Winkler H; c Institute of Pharmacology and Toxicology, University of Zurich-Vetsuisse , Switzerland. Tarik M; d Energy and Environment Research Division , Paul Scherrer Institute (PSI) , Switzerland. Ludwig C; d Energy and Environment Research Division , Paul Scherrer Institute (PSI) , Switzerland.; e E´cole Polytechnique Fe´de´rale de Lausanne (EPFL), ENAC-IIE , Lausanne , Switzerland. Naegeli H; c Institute of Pharmacology and Toxicology, University of Zurich-Vetsuisse , Switzerland. Langhans W; a Department of Health Sciences and Technology , ETH Zürich , Switzerland. Zimmermann MB; a Department of Health Sciences and Technology , ETH Zürich , Switzerland. SturlaSJ; a Department of Health Sciences and Technology , ETH Zürich , Switzerland. Trantakis IA; a Department of Health Sciences and Technology , ETH Zürich , Switzerland.
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Nanotoxicology [Nanotoxicology] 2017 May; Vol. 11 (4), pp. 496-506. Date of Electronic Publication: 2017 Apr 20.
Minor Groove 3-Deaza-Adenosine Analogues: Synthesis and Bypass in Translesion DNA Synthesis.
Autorzy:
Malvezzi S; Department of Health Sciences and Technology, ETH Zurich, Schmelzbergstrasse 9, 8092, Zurich, Switzerland. Angelov T; Department of Health Sciences and Technology, ETH Zurich, Schmelzbergstrasse 9, 8092, Zurich, Switzerland. SturlaSJ; Department of Health Sciences and Technology, ETH Zurich, Schmelzbergstrasse 9, 8092, Zurich, Switzerland.
Acrolein contributes strongly to antimicrobial and heterocyclic amine transformation activities of reuterin.
Autorzy:
Engels C; Laboratory of Food Biotechnology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Schwab C; Laboratory of Food Biotechnology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Zhang J; Laboratory of Food Nutrition and Toxicology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Stevens MJ; Laboratory of Food Biotechnology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Bieri C; Laboratory of Food Biotechnology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Ebert MO; Laboratory of Organic Chemistry, Department of Chemistry and Applied Sciences, ETH Zurich, Zurich, Switzerland. McNeill K; Laboratory of Environmental Chemistry, Institute of Biogeochemistry and Pollutant Dynamics, Department of Environmental Systems Science, ETH Zurich, Zurich, Switzerland. SturlaSJ; Laboratory of Food Nutrition and Toxicology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Lacroix C; Laboratory of Food Biotechnology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.
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Źródło:
Scientific reports [Sci Rep] 2016 Nov 07; Vol. 6, pp. 36246. Date of Electronic Publication: 2016 Nov 07.
The strict anaerobic gut microbe Eubacterium hallii transforms the carcinogenic dietary heterocyclic amine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Autorzy:
Fekry MI; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Engels C; Laboratory of Food Biotechnology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Zhang J; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Schwab C; Laboratory of Food Biotechnology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Lacroix C; Laboratory of Food Biotechnology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. SturlaSJ; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Chassard C; Laboratory of Food Biotechnology, Institute of Food, Nutrition and Health, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.
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Źródło:
Environmental microbiology reports [Environ Microbiol Rep] 2016 Apr; Vol. 8 (2), pp. 201-9. Date of Electronic Publication: 2016 Jan 28.
Sulforaphane Preconditioning Sensitizes Human Colon Cancer Cells towards the Bioreductive Anticancer Prodrug PR-104A.
Autorzy:
Erzinger MM; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Bovet C; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Hecht KM; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Senger S; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Winiker P; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. Sobotzki N; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland. Cristea S; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.; SIB Swiss Institute of Bioinformatics, Basel, Switzerland. Beerenwinkel N; Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.; SIB Swiss Institute of Bioinformatics, Basel, Switzerland. Shay JW; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America. Marra G; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland. Wollscheid B; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.; BioMedical Proteomics Platform (BMPP), ETH Zurich, Zurich, Switzerland. SturlaSJ; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.
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Źródło:
PloS one [PLoS One] 2016 Mar 07; Vol. 11 (3), pp. e0150219. Date of Electronic Publication: 2016 Mar 07 (Print Publication: 2016).
Hydrogen bonding or stacking interactions in differentiating duplex stability in oligonucleotides containing synthetic nucleoside probes for alkylated DNA.
Autorzy:
Gahlon HL; Department of Health Sciences and Technology, ETH Zürich, Schmelzbergstrasse 9, 8092 Zürich, Switzerland. SturlaSJ
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