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Tytuł:
Glycolysis is reduced in dengue virus 2 infected liver cells.
Autorzy:
Chumchanchira C; PhD Degree Program in Biology (International Program), Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand.; Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, 73170, Thailand.
Ramphan S; Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, 73170, Thailand.
Sornjai W; Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, 73170, Thailand.
Roytrakul S; National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency, Khlong Luang, Pathum Thani, 12120, Thailand.
Lithanatudom P; Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand. pathrapol_.
Smith DR; Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, 73170, Thailand. duncan_r_.
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Źródło:
Scientific reports [Sci Rep] 2024 Apr 09; Vol. 14 (1), pp. 8355. Date of Electronic Publication: 2024 Apr 09.
Typ publikacji:
Journal Article
MeSH Terms:
Dengue Virus*/physiology
Dengue*
Humans ; Proteomics ; NAD/metabolism ; Hepatocytes/metabolism ; Glycolysis ; Liver/metabolism ; Virus Replication ; Proteome/metabolism ; Glyceraldehyde-3-Phosphate Dehydrogenases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HBV promotes its replication by up-regulating RAD51C gene expression.
Autorzy:
Peng TW; Department of Clinical Laboratory, Shanghai Gongli Hospital, the Second Military Medical University, Shanghai, 200135, China.
Ma QF; Department of Clinical Laboratory, Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430077, China.
Li J; China Medical Tribune, Beijing, 100009, China.
Wang X; Department of Clinical Laboratory, Shanghai Gongli Hospital, the Second Military Medical University, Shanghai, 200135, China.
Zhang CH; Department of Clinical Laboratory, Shanghai Gongli Hospital, the Second Military Medical University, Shanghai, 200135, China.
Ma J; Department of Clinical Laboratory, Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430077, China.
Li JY; Department of Clinical Laboratory, Liyuan Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430077, China.
Wang W; Department of Clinical Laboratory, Wuhan Fourth Hospital, Wuhan, 430034, China. .
Zhu CL; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan, 430060, China. .
Liu XH; Department of Clinical Laboratory, Shanghai Gongli Hospital, the Second Military Medical University, Shanghai, 200135, China. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 31; Vol. 14 (1), pp. 2607. Date of Electronic Publication: 2024 Jan 31.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/pathology
Hepatitis B, Chronic*
Liver Neoplasms*/pathology
Hepatitis B*/complications
Hepatitis B*/genetics
Humans ; Hepatitis B virus/genetics ; Gene Expression ; Virus Replication ; DNA-Binding Proteins/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A computational spatial whole-Cell model for hepatitis B viral infection and drug interactions.
Autorzy:
Ghaemi Z; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA. .; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA. .; National Science Foundation Science and Technology Center for Quantitative Cell Biology, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA. .
Nafiu O; Carle-Illinois College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
Tajkhorshid E; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.; National Science Foundation Science and Technology Center for Quantitative Cell Biology, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
Gruebele M; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.; National Science Foundation Science and Technology Center for Quantitative Cell Biology, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.; Carle-Illinois College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.; Department of Physics, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
Hu J; Department of Microbiology and Immunology, Pennsylvania State University, Hershey, PA, 17033, USA.
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 04; Vol. 13 (1), pp. 21392. Date of Electronic Publication: 2023 Dec 04.
Typ publikacji:
Journal Article
MeSH Terms:
Hepatitis B*
Virus Diseases*
Humans ; Hepatitis B virus ; Virus Replication/genetics ; DNA, Viral/genetics ; DNA, Viral/metabolism ; Drug Interactions ; DNA, Circular/genetics ; DNA, Circular/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Generation of "OP7 chimera" defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in mice.
Autorzy:
Dogra T; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Magdeburg, Germany.
Pelz L; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Magdeburg, Germany.
Boehme JD; Institute of Medical Microbiology, Infection Prevention and Control, Infection Immunology Group, Health Campus Immunology, Infectiology and Inflammation, Otto Von Guericke University Magdeburg, Magdeburg, Germany.; Immune Regulation Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Kuechler J; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Magdeburg, Germany.
Kershaw O; Department of Veterinary Pathology, Freie Universität Berlin, Berlin, Germany.
Marichal-Gallardo P; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Magdeburg, Germany.
Baelkner M; Institute of Medical Microbiology, Infection Prevention and Control, Infection Immunology Group, Health Campus Immunology, Infectiology and Inflammation, Otto Von Guericke University Magdeburg, Magdeburg, Germany.; Immune Regulation Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Hein MD; Bioprocess Engineering, Otto Von Guericke University Magdeburg, Magdeburg, Germany.
Gruber AD; Department of Veterinary Pathology, Freie Universität Berlin, Berlin, Germany.
Benndorf D; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Magdeburg, Germany.; Bioprocess Engineering, Otto Von Guericke University Magdeburg, Magdeburg, Germany.
Genzel Y; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Magdeburg, Germany.
Bruder D; Institute of Medical Microbiology, Infection Prevention and Control, Infection Immunology Group, Health Campus Immunology, Infectiology and Inflammation, Otto Von Guericke University Magdeburg, Magdeburg, Germany.; Immune Regulation Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Kupke SY; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Magdeburg, Germany. .
Reichl U; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Magdeburg, Germany.; Bioprocess Engineering, Otto Von Guericke University Magdeburg, Magdeburg, Germany.
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 28; Vol. 13 (1), pp. 20936. Date of Electronic Publication: 2023 Nov 28.
Typ publikacji:
Journal Article
MeSH Terms:
Influenza, Human*
Coinfection*
Influenza A virus*/genetics
Animals ; Mice ; Humans ; Defective Viruses/genetics ; Virus Replication ; Antiviral Agents/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
USP18 enhances dengue virus replication by regulating mitochondrial DNA release.
Autorzy:
Lai JH; Department of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Chang Gung Memorial Hospital, Lin-Kou, Tao-Yuan, Taiwan, ROC. .
Wu DW; Department of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Chang Gung Memorial Hospital, Lin-Kou, Tao-Yuan, Taiwan, ROC.
Wu CH; Department of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Chang Gung Memorial Hospital, Lin-Kou, Tao-Yuan, Taiwan, ROC.
Hung LF; Institute of Cellular and System Medicine, National Health Research Institute, Zhunan, Taiwan, ROC.
Huang CY; Institute of Cellular and System Medicine, National Health Research Institute, Zhunan, Taiwan, ROC.
Ka SM; Graduate Institute of Aerospace and Undersea Medicine, Department of Medicine, National Defense Medical Center, Taipei, Taiwan, ROC.
Chen A; Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
Ho LJ; Institute of Cellular and System Medicine, National Health Research Institute, Zhunan, Taiwan, ROC. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 17; Vol. 13 (1), pp. 20126. Date of Electronic Publication: 2023 Nov 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA, Mitochondrial*
Dengue*
Humans ; Interferon-alpha ; Mitochondria/metabolism ; Virus Replication ; Ubiquitin Thiolesterase/genetics ; Ubiquitin Thiolesterase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Role of an RNA pseudoknot involving the polyA tail in replication of Pepino mosaic potexvirus and related plant viruses.
Autorzy:
Olsthoorn RCL; Leiden Institute of Chemistry, University of Leiden, P.O. Box 9502, 2300 RA, Leiden, The Netherlands. .
Owen CA; Department of Sustainable Agriculture, Mediterranean Agronomic Institute of Chania, Alsylio Agrokepion, 73100, Chania, Crete, Greece.
Livieratos IC; Department of Sustainable Agriculture, Mediterranean Agronomic Institute of Chania, Alsylio Agrokepion, 73100, Chania, Crete, Greece.
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Źródło:
Scientific reports [Sci Rep] 2022 Jul 07; Vol. 12 (1), pp. 11532. Date of Electronic Publication: 2022 Jul 07.
Typ publikacji:
Journal Article
MeSH Terms:
Solanum lycopersicum*/virology
Potexvirus*/genetics
Potexvirus*/physiology
Virus Replication*
3' Untranslated Regions/genetics ; Plant Diseases/virology ; RNA, Viral/chemistry
SCR Organism:
Pepino mosaic virus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Shrimp (Penaeus vannamei) survive white spot syndrome virus infection by behavioral fever.
Autorzy:
Rakhshaninejad M; Laboratory of Virology, Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium. .
Zheng L; Laboratory of Virology, Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium.
Nauwynck H; Laboratory of Virology, Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium.
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 21; Vol. 13 (1), pp. 18034. Date of Electronic Publication: 2023 Oct 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Penaeidae*
White spot syndrome virus 1*
Animals ; Temperature ; Virus Replication
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Aedes albopictus salivary adenosine deaminase is an immunomodulatory factor facilitating dengue virus replication.
Autorzy:
Mu X; Department of Parasitology, Provincial Key Laboratory of Modern Pathogen Biology, College of Basic Medical Sciences, Guizhou Medical University, Guiyang, 550025, Guizhou, China.; Department of Reproductive Medicine, People's Hospital of Anshun City Guizhou Province, Anshun, 561000, Guizhou, China.
Lin Z; Department of Parasitology, Provincial Key Laboratory of Modern Pathogen Biology, College of Basic Medical Sciences, Guizhou Medical University, Guiyang, 550025, Guizhou, China.
Sun Y; The Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Chen L; The Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Lv Q; Xi'an Peihua University, Xi'an, 710065, Shaanxi, China.
Ji C; Department of Medical Technology, Guiyang Healthcare Vocational University, Guiyang, Guizhou, China.
Kuang X; Department of Parasitology, Provincial Key Laboratory of Modern Pathogen Biology, College of Basic Medical Sciences, Guizhou Medical University, Guiyang, 550025, Guizhou, China.
Li W; Department of Parasitology, Provincial Key Laboratory of Modern Pathogen Biology, College of Basic Medical Sciences, Guizhou Medical University, Guiyang, 550025, Guizhou, China.
Shang Z; Department of Immunology, College of Basic Medicine, Guizhou Medical University, Guiyang, 550025, China.
Cheng J; Department of Parasitology, Provincial Key Laboratory of Modern Pathogen Biology, College of Basic Medical Sciences, Guizhou Medical University, Guiyang, 550025, Guizhou, China.
Nie Y; Department of Parasitology, Provincial Key Laboratory of Modern Pathogen Biology, College of Basic Medical Sciences, Guizhou Medical University, Guiyang, 550025, Guizhou, China.
Li Z; Department of Immunology, College of Basic Medicine, Guizhou Medical University, Guiyang, 550025, China. .
Wu J; Department of Parasitology, Provincial Key Laboratory of Modern Pathogen Biology, College of Basic Medical Sciences, Guizhou Medical University, Guiyang, 550025, Guizhou, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 04; Vol. 13 (1), pp. 16660. Date of Electronic Publication: 2023 Oct 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dengue Virus*/physiology
Aedes*
Dengue*
Animals ; Mosquito Vectors ; Tumor Necrosis Factor-alpha ; Adenosine Deaminase ; Interleukin-6 ; Virus Replication ; Immunity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication.
Autorzy:
Montezano AC; Research Institute of the McGill University Health Centre (RI-MUHC), Site Glen-Block E-Office: E01.3362, 1001, Boul. Decarie, Montreal, QC, H4A3J1, Canada. .; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK. .
Camargo LL; Research Institute of the McGill University Health Centre (RI-MUHC), Site Glen-Block E-Office: E01.3362, 1001, Boul. Decarie, Montreal, QC, H4A3J1, Canada.
Mary S; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Neves KB; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.
Rios FJ; Research Institute of the McGill University Health Centre (RI-MUHC), Site Glen-Block E-Office: E01.3362, 1001, Boul. Decarie, Montreal, QC, H4A3J1, Canada.
Stein R; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Lopes RA; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Beattie W; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Thomson J; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Herder V; MRC Centre for Virus Research, University of Glasgow, Glasgow, UK.
Szemiel AM; MRC Centre for Virus Research, University of Glasgow, Glasgow, UK.
McFarlane S; MRC Centre for Virus Research, University of Glasgow, Glasgow, UK.
Palmarini M; MRC Centre for Virus Research, University of Glasgow, Glasgow, UK.
Touyz RM; Research Institute of the McGill University Health Centre (RI-MUHC), Site Glen-Block E-Office: E01.3362, 1001, Boul. Decarie, Montreal, QC, H4A3J1, Canada. .; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK. .; McGill University, Montreal, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 28; Vol. 13 (1), pp. 14086. Date of Electronic Publication: 2023 Aug 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Endothelial Cells*
COVID-19*
Humans ; Spike Glycoprotein, Coronavirus ; Angiotensin-Converting Enzyme 2 ; SARS-CoV-2 ; Inflammation ; Virus Replication ; RNA, Double-Stranded
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The non-classical major histocompatibility complex II protein SLA-DM is crucial for African swine fever virus replication.
Autorzy:
Pannhorst K; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, 17493, Greifswald-Insel Riems, Germany. .
Carlson J; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, 17493, Greifswald-Insel Riems, Germany.; Ceva Animal Health, Greifswald-Insel Riems, Germany.
Hölper JE; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, 17493, Greifswald-Insel Riems, Germany.
Grey F; The Roslin Institute, University of Edinburgh, Midlothian, UK.
Baillie JK; The Roslin Institute, University of Edinburgh, Midlothian, UK.
Höper D; Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.
Wöhnke E; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, 17493, Greifswald-Insel Riems, Germany.
Franzke K; Institute of Infectology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.
Karger A; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, 17493, Greifswald-Insel Riems, Germany.
Fuchs W; Institute of Molecular Virology and Cell Biology, Friedrich-Loeffler-Institut, Südufer 10, 17493, Greifswald-Insel Riems, Germany.
Mettenleiter TC; Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany.
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 21; Vol. 13 (1), pp. 10342. Date of Electronic Publication: 2023 Aug 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
African Swine Fever Virus*/genetics
African Swine Fever*/genetics
Craniocerebral Trauma*
Animals ; Swine ; DNA Replication ; DNA, Viral ; Virus Replication/genetics ; Histocompatibility Antigens Class II/genetics ; Membrane Proteins ; Major Histocompatibility Complex
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparison of genome replication fidelity between SARS-CoV-2 and influenza A virus in cell culture.
Autorzy:
Kawasaki Y; Department of Emerging Infectious Diseases, National Research Center for the Control and Prevention of Infectious Diseases (CCPID), Nagasaki University, 1-12-4 Sakamoto, Nagasaki, Nagasaki, 852-8523, Japan.; Department of Emerging Infectious Diseases, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 1-12-4 Sakamoto, Nagasaki, Nagasaki, 852-8523, Japan.
Abe H; Department of Emerging Infectious Diseases, National Research Center for the Control and Prevention of Infectious Diseases (CCPID), Nagasaki University, 1-12-4 Sakamoto, Nagasaki, Nagasaki, 852-8523, Japan.; Department of Emerging Infectious Diseases, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 1-12-4 Sakamoto, Nagasaki, Nagasaki, 852-8523, Japan.
Yasuda J; Department of Emerging Infectious Diseases, National Research Center for the Control and Prevention of Infectious Diseases (CCPID), Nagasaki University, 1-12-4 Sakamoto, Nagasaki, Nagasaki, 852-8523, Japan. .; Department of Emerging Infectious Diseases, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 1-12-4 Sakamoto, Nagasaki, Nagasaki, 852-8523, Japan. .; Graduate School of Biomedical Science, Nagasaki University, 1-12-4 Sakamoto, Nagasaki, Nagasaki, 852-8523, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 11; Vol. 13 (1), pp. 13105. Date of Electronic Publication: 2023 Aug 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*
Influenza A virus*/genetics
Humans ; SARS-CoV-2/genetics ; RNA-Dependent RNA Polymerase/genetics ; Virus Replication/genetics ; Cell Culture Techniques ; RNA, Viral/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Activation of the NLRP3 inflammasome and elevation of interleukin-1β secretion in infection by sever fever with thrombocytopenia syndrome virus.
Autorzy:
Li Z; Medical School and Jiangsu Provincial Key Laboratory of Medicine, Nanjing University, Nanjing, China. .; Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, 210009, China. .
Hu J; Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, 210009, China.
Bao C; Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, 210009, China.
Gao C; Medical School and Jiangsu Provincial Key Laboratory of Medicine, Nanjing University, Nanjing, China.
Zhang N; Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, 210009, China.
Cardona CJ; Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, University of Minnesota at Twin Cities, 300D Veterinary Science Building, 1971 Commonwealth Avenue, Saint Paul, MN, 55108, USA.
Xing Z; Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, University of Minnesota at Twin Cities, 300D Veterinary Science Building, 1971 Commonwealth Avenue, Saint Paul, MN, 55108, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Feb 16; Vol. 12 (1), pp. 2573. Date of Electronic Publication: 2022 Feb 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Virus Replication*
Bunyaviridae Infections/*complications
Inflammasomes/*immunology
Interleukin-1beta/*metabolism
NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism
Phlebovirus/*isolation & purification
Severe Fever with Thrombocytopenia Syndrome/*pathology
Animals ; Bunyaviridae Infections/virology ; Case-Control Studies ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; Severe Fever with Thrombocytopenia Syndrome/etiology ; Severe Fever with Thrombocytopenia Syndrome/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Country-specific optimization strategy for testing through contact tracing can help maintain a low reproduction number ([Formula: see text]) during unlock.
Autorzy:
Sarma U; Vantage Research, Sivasamy St, CIT Colony, Mylapore, Chennai, Tamil Nadu 600004 India.
Ghosh B; Center for Computational Natural Sciences, International Institute of Information Technology, Hyderabad, 500032 India.
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Źródło:
Scientific reports [Sci Rep] 2022 Jan 07; Vol. 12 (1), pp. 212. Date of Electronic Publication: 2022 Jan 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Contact Tracing*
Epidemiological Models*
Physical Distancing*
Quarantine*
Virus Replication*
COVID-19/*prevention & control
Disease Transmission, Infectious/*prevention & control
SARS-CoV-2/*growth & development
COVID-19/epidemiology ; COVID-19/transmission ; COVID-19/virology ; COVID-19 Testing ; Carrier State ; Humans ; Metadata ; SARS-CoV-2/pathogenicity ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Therapeutic interfering particles exploiting viral replication and assembly mechanisms show promising performance: a modelling study.
Autorzy:
Fatehi F; York Cross-disciplinary Centre for Systems Analysis, University of York, York, YO10 5GE, UK.; Department of Mathematics, University of York, York, YO10 5DD, UK.
Bingham RJ; York Cross-disciplinary Centre for Systems Analysis, University of York, York, YO10 5GE, UK.; Department of Mathematics, University of York, York, YO10 5DD, UK.; Department of Biology, University of York, York, YO10 5DD, UK.
Dechant PP; York Cross-disciplinary Centre for Systems Analysis, University of York, York, YO10 5GE, UK.; Department of Mathematics, University of York, York, YO10 5DD, UK.; School of Science, Technology and Health, York St John University, York, YO31 7EX, UK.
Stockley PG; Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, LS2 9JT, UK. .
Twarock R; York Cross-disciplinary Centre for Systems Analysis, University of York, York, YO10 5GE, UK. .; Department of Mathematics, University of York, York, YO10 5DD, UK. .; Department of Biology, University of York, York, YO10 5DD, UK. .
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Źródło:
Scientific reports [Sci Rep] 2021 Dec 13; Vol. 11 (1), pp. 23847. Date of Electronic Publication: 2021 Dec 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Models, Theoretical*
Virus Assembly*
Virus Replication*
Hepacivirus/*physiology
Hepatitis C/*virology
Virion/*chemistry
Antiviral Agents/therapeutic use ; Hepatitis C/drug therapy ; Humans ; RNA, Viral/chemistry ; RNA, Viral/genetics ; RNA, Viral/therapeutic use ; Virion/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
High accumulation of Mx2 renders limited multiplication of oncolytic herpes simplex virus-1 in human tumor cells.
Autorzy:
Ren Y; Shenzhen International Institute for Biomedical Research, Longhua District, Shenzhen, 518116, Guangdong, China.; Research Center for Reproduction and Health Development, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.
Chen M; School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, Guangdong, China.
Wu G; School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, 511436, Guangdong, China.
Ji D; Shanghai Cancer Center and Shanghai Medical College, Fudan University, Shanghai, China.
Zhou GG; Shenzhen International Institute for Biomedical Research, Longhua District, Shenzhen, 518116, Guangdong, China.
Ren PG; Research Center for Reproduction and Health Development, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China. .
Fu W; Shenzhen International Institute for Biomedical Research, Longhua District, Shenzhen, 518116, Guangdong, China. .; Research Center for Reproduction and Health Development, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China. .
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Źródło:
Scientific reports [Sci Rep] 2021 Oct 27; Vol. 11 (1), pp. 21227. Date of Electronic Publication: 2021 Oct 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Virus Replication*
Brain Neoplasms/*virology
Glioblastoma/*virology
Herpesvirus 1, Human/*physiology
Myxovirus Resistance Proteins/*metabolism
Brain Neoplasms/metabolism ; Cell Line, Tumor ; DEAD-box RNA Helicases/genetics ; DEAD-box RNA Helicases/metabolism ; Glioblastoma/metabolism ; Herpesvirus 1, Human/pathogenicity ; Humans ; Immunity, Innate ; Interferon Regulatory Factor-3/genetics ; Interferon Regulatory Factor-3/metabolism ; Interferon-alpha/genetics ; Interferon-alpha/metabolism ; Myeloid Differentiation Factor 88/genetics ; Myeloid Differentiation Factor 88/metabolism ; Myxovirus Resistance Proteins/genetics
Czasopismo naukowe
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Tytuł:
Prediction of severe adverse events, modes of action and drug treatments for COVID-19's complications.
Autorzy:
Astore C; Center for the Study of Systems Biology, School of Biological Sciences, Georgia Institute of Technology, 950 Atlantic Drive, N.W., Atlanta, GA, 30332, USA.
Zhou H; Center for the Study of Systems Biology, School of Biological Sciences, Georgia Institute of Technology, 950 Atlantic Drive, N.W., Atlanta, GA, 30332, USA.
Jacob J; Emory Vaccine Center, Emory University, Atlanta, GA, 30329, USA.; Yerkes National Primate Research Center, Emory University, Atlanta, GA, 30329, USA.; Department of Microbiology and Immunology, Emory Vaccine Center, School of Medicine, Emory University, Atlanta, GA, 30329, USA.
Skolnick J; Center for the Study of Systems Biology, School of Biological Sciences, Georgia Institute of Technology, 950 Atlantic Drive, N.W., Atlanta, GA, 30332, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Oct 21; Vol. 11 (1), pp. 20864. Date of Electronic Publication: 2021 Oct 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Virus Replication*
COVID-19 Drug Treatment*
COVID-19/*complications
COVID-19/*diagnosis
Computational Biology/*methods
Neoplasms/*complications
Nervous System Diseases/*complications
Thrombosis/*complications
Benchmarking ; Comorbidity ; Computer Simulation ; Cytokine Release Syndrome ; Drug Discovery ; Humans ; Machine Learning ; Molecular Medicine ; Phenotype ; SARS-CoV-2 ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Formation of nuclear CPSF6/CPSF5 biomolecular condensates upon HIV-1 entry into the nucleus is important for productive infection.
Autorzy:
Luchsinger C; Department of Microbiology and Immunology, Albert Einstein College of Medicine, 1301 Morris Park - Price Center 501, Bronx, NY, 10461, USA.
Lee K; Basic Research Laboratory, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, 21702, USA.
Mardones GA; Facultad de Medicina Y Ciencia, Universidad San Sebastian, Arturo Prat 154, Valdivia, Chile.
KewalRamani VN; Basic Research Laboratory, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, 21702, USA.
Diaz-Griffero F; Department of Microbiology and Immunology, Albert Einstein College of Medicine, 1301 Morris Park - Price Center 501, Bronx, NY, 10461, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 06; Vol. 13 (1), pp. 10974. Date of Electronic Publication: 2023 Jul 06.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
HIV Infections*
HIV Seropositivity*/metabolism
HIV-1*/genetics
Humans ; Biomolecular Condensates ; Capsid/metabolism ; Capsid Proteins/metabolism ; Cell Nucleus/metabolism ; mRNA Cleavage and Polyadenylation Factors/genetics ; mRNA Cleavage and Polyadenylation Factors/metabolism ; Virus Replication
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Inhibitory effect of β-escin on Zika virus infection through the interruption of viral binding, replication, and stability.
Autorzy:
Lai ZZ; Graduate Institute of Medical Science, National Defense Medical Center, Taipei, 114, Taiwan.; Department and Graduate Institute of Pharmacology, National Defense Medical Center, Taipei, 114, Taiwan.; Department of Pharmacy Practice, Tri-Service General Hospital, National Defense Medical Center, Taipei, 114, Taiwan.
Shen HH; Department and Graduate Institute of Pharmacology, National Defense Medical Center, Taipei, 114, Taiwan.
Lee YM; Department and Graduate Institute of Pharmacology, National Defense Medical Center, Taipei, 114, Taiwan. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jun 20; Vol. 13 (1), pp. 10014. Date of Electronic Publication: 2023 Jun 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Zika Virus Infection*/drug therapy
Zika Virus*/genetics
Dengue*/drug therapy
Humans ; Escin/pharmacology ; Escin/therapeutic use ; Virus Attachment ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; RNA, Viral/therapeutic use ; Virus Replication
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Subgenomic flavivirus RNA (sfRNA) associated with Asian lineage Zika virus identified in three species of Ugandan bats (family Pteropodidae).
Autorzy:
Fagre AC; Colorado State University, Fort Collins, CO, USA.
Lewis J; Colorado State University, Fort Collins, CO, USA.
Miller MR; Colorado State University, Fort Collins, CO, USA.
Mossel EC; Centers for Disease Control and Prevention, Fort Collins, CO, USA.
Lutwama JJ; Uganda Virus Research Institute, Entebbe, Uganda.
Nyakarahuka L; Uganda Virus Research Institute, Entebbe, Uganda.
Nakayiki T; Uganda Virus Research Institute, Entebbe, Uganda.
Kityo R; Makerere University, Kampala, Uganda.
Nalikka B; Makerere University, Kampala, Uganda.
Towner JS; Centers for Disease Control and Prevention, Atlanta, GA, USA.
Amman BR; Centers for Disease Control and Prevention, Atlanta, GA, USA.
Sealy TK; Centers for Disease Control and Prevention, Atlanta, GA, USA.
Foy B; Colorado State University, Fort Collins, CO, USA.
Schountz T; Colorado State University, Fort Collins, CO, USA.
Anderson J; Colorado State University, Fort Collins, CO, USA.
Kading RC; Colorado State University, Fort Collins, CO, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Apr 16; Vol. 11 (1), pp. 8370. Date of Electronic Publication: 2021 Apr 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Cell Lineage*
Genome, Viral*
Virus Replication*
Chiroptera/*virology
RNA, Viral/*genetics
Zika Virus/*isolation & purification
Zika Virus Infection/*diagnosis
Animals ; Chiroptera/genetics ; Chlorocebus aethiops ; Female ; Host-Pathogen Interactions ; Male ; RNA Stability ; Uganda/epidemiology ; Vero Cells ; Zika Virus Infection/epidemiology ; Zika Virus Infection/virology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Identification of two different coagulation phenotypes in people living with HIV with undetectable viral replication.
Autorzy:
Fink A; Viro-Immunology Research Unit, Department of Infectious Diseases 8632, Rigshospitalet, Copenhagen University Hospital, University of Copenhagen, Blegdamsvej 9B, 2100, Copenhagen Ø, Denmark.
Knudsen AD; Viro-Immunology Research Unit, Department of Infectious Diseases 8632, Rigshospitalet, Copenhagen University Hospital, University of Copenhagen, Blegdamsvej 9B, 2100, Copenhagen Ø, Denmark.
Thudium RF; Viro-Immunology Research Unit, Department of Infectious Diseases 8632, Rigshospitalet, Copenhagen University Hospital, University of Copenhagen, Blegdamsvej 9B, 2100, Copenhagen Ø, Denmark.
Von Stemann JH; Department of Clinical Immunology 2034, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Afzal S; The Copenhagen General Population Study, Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.
Lundgren J; CHIP, Department of Infectious Diseases 8632, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Kirkegaard-Klitbo DM; Department of Infectious Diseases, Hvidovre Hospital, University of Copenhagen, Hvidovre, Denmark.
Ostrowski SR; Department of Clinical Immunology 2034, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
Nordestgaard BG; The Copenhagen General Population Study, Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Nielsen SD; Viro-Immunology Research Unit, Department of Infectious Diseases 8632, Rigshospitalet, Copenhagen University Hospital, University of Copenhagen, Blegdamsvej 9B, 2100, Copenhagen Ø, Denmark. .
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Źródło:
Scientific reports [Sci Rep] 2021 Feb 23; Vol. 11 (1), pp. 4383. Date of Electronic Publication: 2021 Feb 23.
Typ publikacji:
Journal Article; Observational Study
MeSH Terms:
Blood Coagulation*
Virus Replication*
HIV Infections/*blood
Adult ; Blood Coagulation Factors/metabolism ; Female ; HIV Infections/virology ; Humans ; Male ; Middle Aged ; Phenotype
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 1118

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