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Tytuł:
Experimental study on the buffering effects of urban trees group in dike-break floods.
Autorzy:
Liu S; School of Water Conservancy, North China University of Water Resources and Electric Power, Zhengzhou, 450046, China.
Zhang X; School of Water Conservancy, North China University of Water Resources and Electric Power, Zhengzhou, 450046, China. .
Xu Z; School of Water Conservancy, North China University of Water Resources and Electric Power, Zhengzhou, 450046, China.
Zhao J; Guangdong Research Institute of Water Resources and Hydropower, Guangzhou, 510610, China.
Dong B; State Key Laboratory of Water Resource and Hydropower Engineering Sciences, Wuhan University, Wuhan, 430072, China.
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 10; Vol. 13 (1), pp. 17096. Date of Electronic Publication: 2023 Oct 10.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Assessing model accuracy using random data split: a simulation study.
Autorzy:
Xu Z; Center for Device Evaluation and Radiological Health (CDRH), FDA, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
De A; Companion Diagnostics, Agilent Technologies, Carpinteria, California, USA.
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Źródło:
Journal of biopharmaceutical statistics [J Biopharm Stat] 2023 Mar; Vol. 33 (2), pp. 131-139. Date of Electronic Publication: 2022 Jun 22.
Typ publikacji:
Journal Article
MeSH Terms:
Computer Simulation*
Humans ; Sample Size ; Bias
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Determinants of quality of life in Parkinson's disease: a perspective of novel clinical subtypes.
Autorzy:
Fan Y; Department of Neurology and National Research Center for Aging and Medicine & National Center for Neurological Disorders, State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Zhang M; Department of Neurology and National Research Center for Aging and Medicine & National Center for Neurological Disorders, State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Liang X; Department of Neurology and National Research Center for Aging and Medicine & National Center for Neurological Disorders, State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Shen B; Department of Neurology and National Research Center for Aging and Medicine & National Center for Neurological Disorders, State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Xu Z; Department of Neurology and National Research Center for Aging and Medicine & National Center for Neurological Disorders, State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Li S; Department of Neurology and National Research Center for Aging and Medicine & National Center for Neurological Disorders, State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Hu T; Department of Neurology and National Research Center for Aging and Medicine & National Center for Neurological Disorders, State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Wu B; Department of Neurology and National Research Center for Aging and Medicine & National Center for Neurological Disorders, State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Zhao J; Department of Neurology and National Research Center for Aging and Medicine & National Center for Neurological Disorders, State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Sun Y; Department of Neurology and National Research Center for Aging and Medicine & National Center for Neurological Disorders, State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Liu F; Department of Neurology and National Research Center for Aging and Medicine & National Center for Neurological Disorders, State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Tang Y; Department of Neurology and National Research Center for Aging and Medicine & National Center for Neurological Disorders, State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Wang J; Department of Neurology and National Research Center for Aging and Medicine & National Center for Neurological Disorders, State Key Laboratory of Medical Neurobiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
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Źródło:
Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2021 Nov; Vol. 8 (11), pp. 2174-2183. Date of Electronic Publication: 2021 Oct 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Quality of Life*
Parkinson Disease/*classification
Parkinson Disease/*physiopathology
Adult ; Aged ; China ; Feasibility Studies ; Female ; Humans ; Male ; Middle Aged ; Patient Acuity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Application of a likelihood ratio test based method for safety signal detection to left ventricular assist devices.
Autorzy:
Jung MY; Division of Biostatistics, Office of Surveillance and Biometrics, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Ward R; Division of Epidemiology, Office of Surveillance and Biometrics, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Xu Z; Division of Biostatistics, Office of Surveillance and Biometrics, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Xu J; Division of Biostatistics, Office of Surveillance and Biometrics, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Yao Z; Division of Biostatistics, Office of Surveillance and Biometrics, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Huang L; Division of Biostatistics, Office of Surveillance and Biometrics, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Tiwari R; Division of Biostatistics, Office of Surveillance and Biometrics, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
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Źródło:
Journal of biopharmaceutical statistics [J Biopharm Stat] 2021 Jan 02; Vol. 31 (1), pp. 47-54. Date of Electronic Publication: 2020 Jun 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Heart Failure*/diagnosis
Heart Failure*/epidemiology
Heart-Assist Devices*/adverse effects
Stroke*
Humans ; Incidence ; Likelihood Functions ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Evaluating medical device adverse event signals using a likelihood ratio test method.
Autorzy:
Xu Z; Center for Devices and Radiology Health, U.S. Food and Drug Administration, MD, USA.
Xu J; Center for Devices and Radiology Health, U.S. Food and Drug Administration, MD, USA.
Yao Z; Center for Devices and Radiology Health, U.S. Food and Drug Administration, MD, USA.
Huang L; Center for Devices and Radiology Health, U.S. Food and Drug Administration, MD, USA.
Jung M; Center for Devices and Radiology Health, U.S. Food and Drug Administration, MD, USA.
Tiwari R; Center for Devices and Radiology Health, U.S. Food and Drug Administration, MD, USA.
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Źródło:
Journal of biopharmaceutical statistics [J Biopharm Stat] 2021 Jan 02; Vol. 31 (1), pp. 37-46. Date of Electronic Publication: 2020 Jun 28.
Typ publikacji:
Journal Article
MeSH Terms:
Adverse Drug Reaction Reporting Systems*
Research Design*
Bayes Theorem ; Databases, Factual ; Humans ; Likelihood Functions
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Correction: Wdr62 is involved in female meiotic initiation via activating JNK signaling and associated with POI in humans.
Autorzy:
Zhou Y
Qin Y
Qin Y
Xu B
Guo T
Ke H
Chen M
Zhang L
Han F
Li Y
Chen M
Behrens A
Wang Y
Xu Z
Chen ZJ
Gao F
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Źródło:
PLoS genetics [PLoS Genet] 2019 Nov 15; Vol. 15 (11), pp. e1008504. Date of Electronic Publication: 2019 Nov 15 (Print Publication: 2019).
Typ publikacji:
Published Erratum
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Role of Plasma Calreticulin in the Prediction of Severity in Septic Patients.
Autorzy:
Xu Z; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou 510120, China.
Yang Y; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou 510120, China.
Zhou J; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou 510120, China.
Huang Y; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou 510120, China.
Wang Y; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou 510120, China.
Zhang Y; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou 510120, China.
Lan Y; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou 510120, China.
Liang J; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou 510120, China.
Liu X; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou 510120, China.
Zhong N; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou 510120, China.
Li Y; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou 510120, China.
Mao P; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou 510120, China.
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Źródło:
Disease markers [Dis Markers] 2019 Sep 12; Vol. 2019, pp. 8792640. Date of Electronic Publication: 2019 Sep 12 (Print Publication: 2019).
Typ publikacji:
Journal Article
MeSH Terms:
Calreticulin/*blood
Sepsis/*blood
Sepsis/*diagnosis
Adult ; Aged ; Aged, 80 and over ; Biomarkers/blood ; Case-Control Studies ; Female ; Humans ; Intensive Care Units ; Male ; Middle Aged ; Prognosis ; ROC Curve ; Retrospective Studies ; Sepsis/mortality ; Sepsis/pathology ; Severity of Illness Index ; Survival Analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Implementing artificial neural networks through bionic construction.
Autorzy:
He H; Institute of Microelectronics, Tsinghua University, Beijing, China.
Yang X; School of Computer Science and Technology, Beijing Institute of Technology, Beijing, China.
Xu Z; Institute of Microelectronics, Tsinghua University, Beijing, China.
Deng N; Institute of Microelectronics, Tsinghua University, Beijing, China.
Shang Y; Institute of Microelectronics, Tsinghua University, Beijing, China.
Liu G; School of Computer Science and Technology, Beijing Institute of Technology, Beijing, China.
Ji M; School of Computer Science and Technology, Beijing Institute of Technology, Beijing, China.
Zheng W; School of Computer Science and Technology, Beijing Institute of Technology, Beijing, China.
Zhao J; School of Computer Science and Technology, Beijing Institute of Technology, Beijing, China.
Dong L; Institute of Microelectronics, Tsinghua University, Beijing, China.
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Źródło:
PloS one [PLoS One] 2019 Feb 22; Vol. 14 (2), pp. e0212368. Date of Electronic Publication: 2019 Feb 22 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Artificial Intelligence*
Bionics*
Neural Networks, Computer*
Drosophila melanogaster/*physiology
Nerve Net/*physiology
Visual Pathways/*physiology
Visual Perception/*physiology
Algorithms ; Animals ; Color ; Machine Learning ; Movement ; Pattern Recognition, Automated
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis.
Autorzy:
Xu D; State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.; College of Biological Science and Engineering, Institute of Life Sciences, Fuzhou University, Fuzhou, China.
Yao M; State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Wang Y; State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Yuan L; Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan, China.
Hoeck JD; CR-UK London Research Institute, London, United Kingdom.
Yu J; State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Liu L; State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Yeap YYC; School of Biomedical Science, Faculty of Medicine, University of Queensland, St Lucia, Australia.
Zhang W; State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Zhang F; State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Feng Y; Sino-Danish College, University of Chinese Academy of Science, Beijing, China.
Ma T; State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Wang Y; College of Biological Science and Engineering, Institute of Life Sciences, Fuzhou University, Fuzhou, China.
Ng DCH; School of Biomedical Science, Faculty of Medicine, University of Queensland, St Lucia, Australia.
Niu X; Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Su B; Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, United States of America.
Behrens A; Adult Stem Cell Laboratory, The Francis Crick Institute, London, United Kingdom.; King's College London, Faculty of Life Sciences and Medicine, Guy's Campus, London, United Kingdom.
Xu Z; State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.; Sino-Danish College, University of Chinese Academy of Science, Beijing, China.; Parkinson's Disease Center, Beijing Institute for Brain Disorders, Beijing, China.
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Źródło:
PLoS biology [PLoS Biol] 2018 Dec 19; Vol. 16 (12), pp. e2006613. Date of Electronic Publication: 2018 Dec 19 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Cycle Proteins/*metabolism
F-Box-WD Repeat-Containing Protein 7/*physiology
MAP Kinase Kinase Kinase 3/*physiology
Microtubule-Associated Proteins/*metabolism
Animals ; Cell Differentiation ; F-Box-WD Repeat-Containing Protein 7/genetics ; Female ; HEK293 Cells ; Humans ; MAP Kinase Kinase Kinase 3/genetics ; MAP Kinase Signaling System ; Male ; Mice ; Mice, Knockout ; Mice, Transgenic ; Microcephaly/genetics ; Microcephaly/physiopathology ; Mitogen-Activated Protein Kinase 8/metabolism ; Nerve Tissue Proteins/metabolism ; Neural Stem Cells/metabolism ; Neurogenesis/physiology ; Phosphorylation ; Protein Binding ; Rats ; Rats, Sprague-Dawley ; Signal Transduction
SCR Disease Name:
Autosomal Recessive Primary Microcephaly
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High-flow nasal cannula in adults with acute respiratory failure and after extubation: a systematic review and meta-analysis.
Autorzy:
Xu Z; State Key Laboratory of Respiratory Diseases, National Clinical Research Center for Respiratory Disease, Guangzhou Institute for Respiratory Health, Guangzhou, China.; Department of Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Li Y; State Key Laboratory of Respiratory Diseases, National Clinical Research Center for Respiratory Disease, Guangzhou Institute for Respiratory Health, Guangzhou, China.; Department of Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Zhou J; State Key Laboratory of Respiratory Diseases, National Clinical Research Center for Respiratory Disease, Guangzhou Institute for Respiratory Health, Guangzhou, China.
Li X; State Key Laboratory of Respiratory Diseases, National Clinical Research Center for Respiratory Disease, Guangzhou Institute for Respiratory Health, Guangzhou, China.; Department of Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Huang Y; State Key Laboratory of Respiratory Diseases, National Clinical Research Center for Respiratory Disease, Guangzhou Institute for Respiratory Health, Guangzhou, China.; Department of Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Liu X; State Key Laboratory of Respiratory Diseases, National Clinical Research Center for Respiratory Disease, Guangzhou Institute for Respiratory Health, Guangzhou, China.
Burns KEA; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada. .; The Keenan Research Centre for Biomedical Science and the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, ON, M5B1W8, Canada. .; Departments of Anesthesia and Physiology, University of Toronto, Toronto, ON, Canada. .
Zhong N; State Key Laboratory of Respiratory Diseases, National Clinical Research Center for Respiratory Disease, Guangzhou Institute for Respiratory Health, Guangzhou, China.
Zhang H; State Key Laboratory of Respiratory Diseases, National Clinical Research Center for Respiratory Disease, Guangzhou Institute for Respiratory Health, Guangzhou, China. .; Department of Critical Care Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. .; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada. .; The Keenan Research Centre for Biomedical Science and the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, ON, M5B1W8, Canada. .; Departments of Anesthesia and Physiology, University of Toronto, Toronto, ON, Canada. .
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Źródło:
Respiratory research [Respir Res] 2018 Oct 16; Vol. 19 (1), pp. 202. Date of Electronic Publication: 2018 Oct 16.
Typ publikacji:
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms:
Airway Extubation/*trends
Cannula/*trends
Oxygen Inhalation Therapy/*trends
Randomized Controlled Trials as Topic/*methods
Respiratory Distress Syndrome/*therapy
Airway Extubation/adverse effects ; Cannula/adverse effects ; Humans ; Oxygen Inhalation Therapy/adverse effects ; Respiratory Distress Syndrome/diagnosis ; Respiratory Distress Syndrome/physiopathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Wdr62 is involved in female meiotic initiation via activating JNK signaling and associated with POI in humans.
Autorzy:
Zhou Y; State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Qin Y; State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Qin Y; Center for Reproductive Medicine of Shandong University, National Research Center for Assisted Reproductive Technology and Reproductive Genetics, The Key Laboratory for Reproductive Endocrinology of Ministry of Education, Jinan, China.
Xu B; State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Guo T; Center for Reproductive Medicine of Shandong University, National Research Center for Assisted Reproductive Technology and Reproductive Genetics, The Key Laboratory for Reproductive Endocrinology of Ministry of Education, Jinan, China.
Ke H; Center for Reproductive Medicine of Shandong University, National Research Center for Assisted Reproductive Technology and Reproductive Genetics, The Key Laboratory for Reproductive Endocrinology of Ministry of Education, Jinan, China.
Chen M; State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Zhang L; State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Han F; State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Li Y; State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Chen M; State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Behrens A; CR-UK London Research Institute, London, United Kingdom.
Wang Y; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Xu Z; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.
Chen ZJ; Center for Reproductive Medicine of Shandong University, National Research Center for Assisted Reproductive Technology and Reproductive Genetics, The Key Laboratory for Reproductive Endocrinology of Ministry of Education, Jinan, China.
Gao F; State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
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Źródło:
PLoS genetics [PLoS Genet] 2018 Aug 13; Vol. 14 (8), pp. e1007463. Date of Electronic Publication: 2018 Aug 13 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Cycle Proteins/*genetics
MAP Kinase Signaling System/*genetics
Microtubule-Associated Proteins/*genetics
Nerve Tissue Proteins/*genetics
Primary Ovarian Insufficiency/*genetics
Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Asian People/genetics ; Cell Cycle Proteins/deficiency ; Cell Cycle Proteins/metabolism ; Disease Models, Animal ; Female ; Gene Deletion ; Gene Expression Regulation ; Germ Cells ; Haploidy ; Humans ; Male ; Meiosis ; Mice ; Mice, Knockout ; Microtubule-Associated Proteins/deficiency ; Microtubule-Associated Proteins/metabolism ; Nerve Tissue Proteins/deficiency ; Nerve Tissue Proteins/metabolism ; Primary Ovarian Insufficiency/diagnosis ; Sequence Analysis, DNA ; Exome Sequencing
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
E90 subunit vaccine protects mice from Zika virus infection and microcephaly.
Autorzy:
Zhu X; State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, 100101, China.
Li C; Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100005, China.; Suzhou Institute of Systems Medicine, Suzhou, 215123, Jiangsu, China.; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
Afridi SK; State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, 100101, China.
Zu S; University of Chinese Academy of Sciences, Beijing, 100101, China.; CAS Key Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Xu JW; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
Quanquin N; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, 90095, USA.
Yang H; Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100005, China.; Suzhou Institute of Systems Medicine, Suzhou, 215123, Jiangsu, China.
Cheng G; Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100005, China. .; Suzhou Institute of Systems Medicine, Suzhou, 215123, Jiangsu, China. .; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, 90095, USA. .
Xu Z; State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China. .; University of Chinese Academy of Sciences, Beijing, 100101, China. .; Parkinson's Disease Center, Beijing Institute for Brain Disorders, Beijing, 100101, China. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2018 Aug 10; Vol. 6 (1), pp. 77. Date of Electronic Publication: 2018 Aug 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Microcephaly/*etiology
Microcephaly/*prevention & control
Vaccines, Subunit/*therapeutic use
Viral Envelope Proteins/*immunology
Zika Virus Infection/*complications
Zika Virus Infection/*therapy
Animals ; Animals, Newborn ; Antibodies/blood ; Body Weight ; Disease Models, Animal ; Embryo, Mammalian ; Female ; Mice ; Mice, Inbred ICR ; Microcephaly/virology ; Nerve Tissue Proteins/metabolism ; Pregnancy ; Prenatal Exposure Delayed Effects/prevention & control ; Prenatal Exposure Delayed Effects/virology ; Time Factors ; Treatment Outcome ; Zika Virus Infection/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cytomegalovirus infection and outcome in immunocompetent patients in the intensive care unit: a systematic review and meta-analysis.
Autorzy:
Li X; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University (Guangzhou Medical University), Guangzhou, China.; Intensive Care Unit, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Huang Y; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University (Guangzhou Medical University), Guangzhou, China.; Intensive Care Unit, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Xu Z; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University (Guangzhou Medical University), Guangzhou, China.; Intensive Care Unit, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Zhang R; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University (Guangzhou Medical University), Guangzhou, China.; Intensive Care Unit, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Liu X; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University (Guangzhou Medical University), Guangzhou, China.; Intensive Care Unit, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Li Y; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University (Guangzhou Medical University), Guangzhou, China. .; Intensive Care Unit, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China. .
Mao P; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University (Guangzhou Medical University), Guangzhou, China. .; Department of Infection Control, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2018 Jun 28; Vol. 18 (1), pp. 289. Date of Electronic Publication: 2018 Jun 28.
Typ publikacji:
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms:
Cytomegalovirus Infections/*mortality
Cytomegalovirus Infections/*therapy
Antiviral Agents/therapeutic use ; Critical Illness ; Cytomegalovirus Infections/immunology ; Humans ; Immunocompetence ; Intensive Care Units/statistics & numerical data ; Length of Stay ; Middle Aged ; Respiration, Artificial ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A single mutation in the prM protein of Zika virus contributes to fetal microcephaly.
Autorzy:
Yuan L; State Key Laboratory of Molecular Developmental Biology, Chinese Academy of Sciences (CAS) Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, CAS, Beijing 100101, China.; University of CAS, Beijing 100101, China.
Huang XY; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Liu ZY; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Zhang F; State Key Laboratory of Molecular Developmental Biology, Chinese Academy of Sciences (CAS) Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, CAS, Beijing 100101, China.; University of CAS, Beijing 100101, China.
Zhu XL; State Key Laboratory of Molecular Developmental Biology, Chinese Academy of Sciences (CAS) Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, CAS, Beijing 100101, China.; University of CAS, Beijing 100101, China.
Yu JY; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Ji X; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Xu YP; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Li G; State Key Laboratory of Molecular Developmental Biology, Chinese Academy of Sciences (CAS) Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, CAS, Beijing 100101, China.; University of CAS, Beijing 100101, China.
Li C; State Key Laboratory of Molecular Developmental Biology, Chinese Academy of Sciences (CAS) Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, CAS, Beijing 100101, China.; University of CAS, Beijing 100101, China.
Wang HJ; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Deng YQ; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Wu M; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, CAS, Beijing 100101, China.
Cheng ML; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.; Graduate School, Anhui Medical University, Hefei 230032, China.
Ye Q; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Xie DY; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.; Graduate School, Anhui Medical University, Hefei 230032, China.
Li XF; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Wang X; National Laboratory of Macromolecules, Institute of Biophysics, CAS, Beijing 100101, China.
Shi W; Shandong Universities Key Laboratory of Etiology and Epidemiology of Emerging Infectious Diseases, Taishan Medical College, Taian 271000, China.
Hu B; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, CAS, Beijing 100101, China.
Shi PY; Department of Biochemistry and Molecular Biology and Department of Pharmacology and Toxicology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555, USA.
Xu Z; State Key Laboratory of Molecular Developmental Biology, Chinese Academy of Sciences (CAS) Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, CAS, Beijing 100101, China.; University of CAS, Beijing 100101, China.; Parkinson's Disease Center, Beijing Institute for Brain Disorders, Beijing 100101, China.
Qin CF; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
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Źródło:
Science (New York, N.Y.) [Science] 2017 Nov 17; Vol. 358 (6365), pp. 933-936. Date of Electronic Publication: 2017 Sep 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microcephaly/*virology
Viral Envelope Proteins/*genetics
Zika Virus/*genetics
Zika Virus/*pathogenicity
Zika Virus Infection/*virology
Americas/epidemiology ; Amino Acid Substitution ; Animals ; Asparagine/genetics ; Cell Line, Tumor ; Cricetinae ; Disease Outbreaks ; Humans ; Incidence ; Mice ; Microcephaly/epidemiology ; Mutation ; Neural Stem Cells/virology ; Polynesia/epidemiology ; Serine/genetics ; Zika Virus Infection/complications ; Zika Virus Infection/epidemiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Interleukin-10/lymphocyte ratio predicts mortality in severe septic patients.
Autorzy:
Li X; State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China.; Intensive Care Unit, The People's Hospital Of Leshan, Sichuan, China.
Xu Z; State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China.; Intensive Care Unit, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Pang X; Intensive Care Unit, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Huang Y; State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China.
Yang B; State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China.
Yang Y; State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China.
Chen K; State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China.
Liu X; Intensive Care Unit, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Mao P; Department of Infection Control, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
Li Y; State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, Guangdong, China.; Intensive Care Unit, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
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Źródło:
PloS one [PLoS One] 2017 Jun 19; Vol. 12 (6), pp. e0179050. Date of Electronic Publication: 2017 Jun 19 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-10/*blood
Lymphocytes/*cytology
Sepsis/*mortality
APACHE ; Adult ; Aged ; Area Under Curve ; Female ; Humans ; Intensive Care Units ; Kaplan-Meier Estimate ; Lymphocyte Count ; Male ; Middle Aged ; Proportional Hazards Models ; ROC Curve ; Sepsis/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms.
Autorzy:
Zhou Z; Roche Pharma Research and Early Development, Chemical Biology, Roche Innovation Center Shanghai, Shanghai, 201203, China.
Hu T; Roche Pharma Research and Early Development, Medicinal Chemistry, Roche Innovation Center Shanghai, Shanghai, 201203, China.
Zhou X; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Shanghai, Shanghai, 201203, China.
Wildum S; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Basel, CH-4070 Basel, Switzerland.
Garcia-Alcalde F; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Basel, CH-4070 Basel, Switzerland.
Xu Z; Roche Pharma Research and Early Development, Chemical Biology, Roche Innovation Center Shanghai, Shanghai, 201203, China.
Wu D; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Shanghai, Shanghai, 201203, China.
Mao Y; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Shanghai, Shanghai, 201203, China.
Tian X; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Shanghai, Shanghai, 201203, China.
Zhou Y; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Shanghai, Shanghai, 201203, China.
Shen F; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Shanghai, Shanghai, 201203, China.
Zhang Z; Roche Pharma Research and Early Development, Medicinal Chemistry, Roche Innovation Center Shanghai, Shanghai, 201203, China.
Tang G; Roche Pharma Research and Early Development, Medicinal Chemistry, Roche Innovation Center Shanghai, Shanghai, 201203, China.
Najera I; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Basel, CH-4070 Basel, Switzerland.
Yang G; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Shanghai, Shanghai, 201203, China.
Shen HC; Roche Pharma Research and Early Development, Medicinal Chemistry, Roche Innovation Center Shanghai, Shanghai, 201203, China.
Young JA; Roche Pharma Research and Early Development, Immunology, Inflammation and Infectious Diseases Discovery and Translational Area, Roche Innovation Center Basel, CH-4070 Basel, Switzerland.
Qin N; Roche Pharma Research and Early Development, Chemical Biology, Roche Innovation Center Shanghai, Shanghai, 201203, China.
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Źródło:
Scientific reports [Sci Rep] 2017 Feb 13; Vol. 7, pp. 42374. Date of Electronic Publication: 2017 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Benzamides/*pharmacology
Hepatitis B virus/*physiology
Pyrimidines/*pharmacology
Virus Replication/*drug effects
Antiviral Agents/pharmacology ; Benzamides/chemistry ; Binding Sites ; Capsid/metabolism ; Crystallography, X-Ray ; DNA Replication/drug effects ; Hep G2 Cells ; Hepatitis B virus/drug effects ; Humans ; Ligands ; Mutation/genetics ; Photoaffinity Labels ; Pyrimidines/chemistry ; Viral Proteins/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity.
Autorzy:
Liu K; West China Developmental &Stem Cell Institute, West China Second Hospital, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, Sichuan 610041, China.; Shenzhen Key Laboratory for Molecular Biology of Neural Development, Laboratory of Developmental and Regenerative Biology, Institute of Biomedicine &Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China.; SARITEX Center for Stem Cell Engineering Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine &Advanced Institute of Translational Medicine, Shanghai 200123, China.; ATCG Corp., BioBay, Suzhou Industrial Park, Suzhou, Jiangsu 215123, China.
Lei R; West China Developmental &Stem Cell Institute, West China Second Hospital, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, Sichuan 610041, China.; Shenzhen Key Laboratory for Molecular Biology of Neural Development, Laboratory of Developmental and Regenerative Biology, Institute of Biomedicine &Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China.; SARITEX Center for Stem Cell Engineering Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine &Advanced Institute of Translational Medicine, Shanghai 200123, China.; ATCG Corp., BioBay, Suzhou Industrial Park, Suzhou, Jiangsu 215123, China.
Li Q; Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province,Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Wang XX; Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province,Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Wu Q; Department of Nutrition, School of Public Health, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
An P; Department of Nutrition, School of Public Health, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
Zhang J; Shenzhen Key Laboratory for Molecular Biology of Neural Development, Laboratory of Developmental and Regenerative Biology, Institute of Biomedicine &Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China.
Zhu M; SARITEX Center for Stem Cell Engineering Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine &Advanced Institute of Translational Medicine, Shanghai 200123, China.; ATCG Corp., BioBay, Suzhou Industrial Park, Suzhou, Jiangsu 215123, China.
Xu Z; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.
Hong Y; Department of Cell Biology &Physiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
Wang F; Department of Nutrition, School of Public Health, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China.
Shen Y; Department of Neurobiology, Key Laboratory of Medical Neurobiology of Ministry of Health of China, Zhejiang Province,Key Laboratory of Neurobiology, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Li H; Shenzhen Key Laboratory for Molecular Biology of Neural Development, Laboratory of Developmental and Regenerative Biology, Institute of Biomedicine &Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, China.
Li H; SARITEX Center for Stem Cell Engineering Translational Medicine, Shanghai East Hospital, Tongji University School of Medicine &Advanced Institute of Translational Medicine, Shanghai 200123, China.; ATCG Corp., BioBay, Suzhou Industrial Park, Suzhou, Jiangsu 215123, China.
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Źródło:
Scientific reports [Sci Rep] 2016 Feb 16; Vol. 6, pp. 21019. Date of Electronic Publication: 2016 Feb 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neuronal Plasticity/*physiology
Receptors, AMPA/*metabolism
Receptors, Transferrin/*metabolism
Animals ; Brain/metabolism ; CA1 Region, Hippocampal/metabolism ; Cell Membrane/metabolism ; Gene Deletion ; Gene Expression ; Long-Term Potentiation ; Mice ; Mice, Knockout ; Neurons/metabolism ; Protein Transport ; Receptors, Transferrin/genetics ; Seizures/genetics ; Seizures/metabolism ; Seizures/mortality ; Synapses/metabolism ; Synaptic Transmission/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
MAZ mediates the cross-talk between CT-1 and NOTCH1 signaling during gliogenesis.
Autorzy:
Liu B; State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University.
Ma A; State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University.; The Institute of Developmental Biology and Molecular Medicine, Fudan University, Shanghai, China, 200433.
Zhang F; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China 100101.
Wang Y; State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University.; The Institute of Developmental Biology and Molecular Medicine, Fudan University, Shanghai, China, 200433.
Li Z; State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University.; The Institute of Developmental Biology and Molecular Medicine, Fudan University, Shanghai, China, 200433.
Li Q; State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University.
Xu Z; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China 100101.; Innovation Center for International Cooperation of Genetics and Development, Fudan University, Shanghai, China, 200433.
Zheng Y; State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University.; The Institute of Developmental Biology and Molecular Medicine, Fudan University, Shanghai, China, 200433.; Innovation Center for International Cooperation of Genetics and Development, Fudan University, Shanghai, China, 200433.
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Źródło:
Scientific reports [Sci Rep] 2016 Feb 12; Vol. 6, pp. 21534. Date of Electronic Publication: 2016 Feb 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cytokines/*metabolism
DNA-Binding Proteins/*metabolism
Neural Stem Cells/*metabolism
Neuroglia/*metabolism
Receptor, Notch1/*metabolism
Signal Transduction/*physiology
Transcription Factors/*metabolism
ADAM10 Protein/biosynthesis ; ADAM10 Protein/genetics ; Amyloid Precursor Protein Secretases/biosynthesis ; Amyloid Precursor Protein Secretases/genetics ; Animals ; Cytokines/genetics ; DNA-Binding Proteins/genetics ; Humans ; Membrane Proteins/biosynthesis ; Membrane Proteins/genetics ; Mice ; NIH 3T3 Cells ; Neural Stem Cells/cytology ; Neuroglia/cytology ; Receptor, Notch1/genetics ; Transcription Factors/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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