Autor: "Ying S" - OpacWWW - Prolib Integro

Skocz do pozycji: 1.

Tytuł:: Discovery of new MD2 inhibitor from chalcone derivatives with anti-inflammatory effects in LPS-induced acute lung injury.
Autorzy:: Zhang Y; Chemical Biology Research Center at School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Wu J; Chemical Biology Research Center at School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Ying S; Chemical Biology Research Center at School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Chen G; Chemical Biology Research Center at School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Wu B; The 2nd Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Xu T; The 2nd Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Liu Z; Chemical Biology Research Center at School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Liu X; Chemical Biology Research Center at School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Huang L; Chemical Biology Research Center at School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Shan X; The 2nd Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Dai Y; The 2nd Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Liang G; Chemical Biology Research Center at School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Apr 27; Vol. 6, pp. 25130. Date of Electronic Publication: 2016 Apr 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Acute Lung Injury/*chemically induced
Acute Lung Injury/*drug therapy
Anti-Inflammatory Agents/*administration & dosage
Anti-Inflammatory Agents/*chemical synthesis
Lymphocyte Antigen 96/*antagonists & inhibitors
Acute Lung Injury/immunology ; Animals ; Anti-Inflammatory Agents/pharmacology ; Chalcone/analogs & derivatives ; Cytokines/metabolism ; Disease Models, Animal ; Gene Expression Regulation/drug effects ; Hydrogen Bonding ; Lipopolysaccharides/adverse effects ; Lymphocyte Antigen 96/chemistry ; MAP Kinase Signaling System/drug effects ; Mice ; Molecular Docking Simulation ; NF-kappa B/metabolism ; RAW 264.7 Cells ; Rats

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