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Wyszukujesz frazę ""deubiquitinating enzymes"" wg kryterium: Temat


Tytuł:
Involvement of the OTUB1-YAP1 axis in driving malignant behaviors of head and neck squamous cell carcinoma.
Autorzy:
Jin S; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Tsunematsu T; Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Horiguchi T; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Mouri Y; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Shao W; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Miyoshi K; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Hagita H; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Sarubo M; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Fujiwara N; Department of Oral Healthcare Management, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Qi G; Guangxi Key Laboratory of Tumor Immunology and Microenvironmental Regulation, Guilin Medical University, Guilin, China.
Ishimaru N; Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Kudo Y; Department of Oral Bioscience, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
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Źródło:
Cancer medicine [Cancer Med] 2023 Dec; Vol. 12 (24), pp. 22156-22169. Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Head and Neck Neoplasms*/genetics
Squamous Cell Carcinoma of Head and Neck*/genetics
Deubiquitinating Enzymes*/metabolism
YAP-Signaling Proteins*/metabolism
Humans ; Cell Line, Tumor ; Ubiquitin Thiolesterase
Czasopismo naukowe
Tytuł:
OTUB1 inhibits breast cancer by non-canonically stabilizing CCN6.
Autorzy:
Zhao Y; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Department of Neurological Rehabilitation, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Ruan J; Department of Pathology, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, China.
Li Z; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Su X; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Chen K; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Lin Y; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Cai Y; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Wang P; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.
Liu B; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Department of Neurological Rehabilitation, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Schlüter D; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany.
Liang G; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.; School of Pharmaceutical Sciences, Hangzhou Medical College, Hangzhou, China.
Wang X; Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.; Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Department of Neurological Rehabilitation, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2023 Aug; Vol. 13 (8), pp. e1385.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinogenesis*
Cell Transformation, Neoplastic*
Deubiquitinating Enzymes*/metabolism
CCN Intercellular Signaling Proteins*/metabolism
Humans ; Blotting, Western ; Cytoplasm ; Proteasome Endopeptidase Complex
Czasopismo naukowe
Tytuł:
Ubiquitin-specific protease 14 targets PFKL-mediated glycolysis to promote the proliferation and migration of oral squamous cell carcinoma.
Autorzy:
Zhang, Xingming (AUTHOR)
Geng, Lou (AUTHOR)
Tang, Yi (AUTHOR)
Wang, Yingying (AUTHOR)
Zhang, Youping (AUTHOR)
Zhu, Chujiao (AUTHOR)
Lei, Hu (AUTHOR)
Xu, Hanzhang (AUTHOR)
Zhu, Qi (AUTHOR)
Wu, Yingli (AUTHOR)
Gu, Wenli (AUTHOR)
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Źródło:
Journal of Translational Medicine. 2/22/2024, Vol. 22 Issue 1, p1-18. 18p.
Czasopismo naukowe
Tytuł:
USP14 exhibits high expression levels in hepatocellular carcinoma and plays a crucial role in promoting the growth of liver cancer cells through the HK2/AKT/P62 axis.
Autorzy:
Zhang, Nannan (AUTHOR)
Zhang, Hui (AUTHOR)
Yang, Xiaobing (AUTHOR)
Xue, Qiang (AUTHOR)
Wang, Quhui (AUTHOR)
Chang, Renan (AUTHOR)
Zhu, Lirong (AUTHOR)
Chen, Zhong (AUTHOR)
Liu, Xiancheng (AUTHOR)
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Źródło:
BMC Cancer. 2/21/2024, Vol. 24 Issue 1, p1-15. 15p.
Czasopismo naukowe
Tytuł:
Deubiquitinating Enzyme Inhibitors Block Chikungunya Virus Replication.
Autorzy:
López LS; Grupo de Virología, Universidad El Bosque, Bogotá 110121, Colombia.
Calvo EP; Grupo de Virología, Universidad El Bosque, Bogotá 110121, Colombia.
Castellanos JE; Grupo de Virología, Universidad El Bosque, Bogotá 110121, Colombia.
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Źródło:
Viruses [Viruses] 2023 Feb 09; Vol. 15 (2). Date of Electronic Publication: 2023 Feb 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chikungunya Fever*/drug therapy
Chikungunya virus*/drug effects
Deubiquitinating Enzymes*/antagonists & inhibitors
Enzyme Inhibitors*/pharmacology
Enzyme Inhibitors*/therapeutic use
Virus Replication*/drug effects
Humans ; HEK293 Cells ; RNA, Viral
Czasopismo naukowe
Tytuł:
A novel proteomic signature of osteoclast differentiation unveils the deubiquitinase UCHL1 as a necessary osteoclastogenic driver.
Autorzy:
Materozzi M; Age Related Diseases Unit, IRCCS Ospedale San Raffaele, Milan, Italy. .; Università Vita-Salute San Raffaele, Milan, Italy. .
Resnati M; Age Related Diseases Unit, IRCCS Ospedale San Raffaele, Milan, Italy.
Facchi C; Age Related Diseases Unit, IRCCS Ospedale San Raffaele, Milan, Italy.; Università Vita-Salute San Raffaele, Milan, Italy.
Trudu M; Age Related Diseases Unit, IRCCS Ospedale San Raffaele, Milan, Italy.; Università Vita-Salute San Raffaele, Milan, Italy.
Orfanelli U; Age Related Diseases Unit, IRCCS Ospedale San Raffaele, Milan, Italy.
Perini T; Age Related Diseases Unit, IRCCS Ospedale San Raffaele, Milan, Italy.; Università Vita-Salute San Raffaele, Milan, Italy.
Gennari L; Department of Medicine, Surgery and Neurosciences, University of Siena, Siena, Italy.
Milan E; Age Related Diseases Unit, IRCCS Ospedale San Raffaele, Milan, Italy. .; Università Vita-Salute San Raffaele, Milan, Italy. .
Cenci S; Age Related Diseases Unit, IRCCS Ospedale San Raffaele, Milan, Italy. .; Università Vita-Salute San Raffaele, Milan, Italy. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 27; Vol. 14 (1), pp. 7290. Date of Electronic Publication: 2024 Mar 27.
Typ publikacji:
Journal Article
MeSH Terms:
Bone Resorption*/metabolism
Osteolysis*/metabolism
Animals ; Mice ; Cell Differentiation/genetics ; Deubiquitinating Enzymes/metabolism ; Kelch-Like ECH-Associated Protein 1/metabolism ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Osteoclasts/metabolism ; Proteomics ; RANK Ligand/metabolism
Czasopismo naukowe
Tytuł:
BRCC3 mediates inflammation and pyroptosis in cerebral ischemia/reperfusion injury by activating the NLRP6 inflammasome.
Autorzy:
Huang X; Department of Pathology, Chongqing Medical University, Chongqing, China.; Department of Pathology, Chongqing Three Gorges Medical College, Wanzhou, China.
Tan J; Department of Pathophysiology, Chongqing Medical University, Chongqing, China.
Ji Y; Department of Pathology, Chongqing Medical University, Chongqing, China.
Luo J; Department of Pathology, Chongqing Medical University, Chongqing, China.; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhao Y; Department of Pathology, Chongqing Medical University, Chongqing, China.
Zhao J; Department of Pathophysiology, Chongqing Medical University, Chongqing, China.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Mar; Vol. 30 (3), pp. e14697.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Ischemia*/metabolism
Reperfusion Injury*/metabolism
Animals ; Humans ; Mice ; Deubiquitinating Enzymes ; Infarction, Middle Cerebral Artery/pathology ; Inflammasomes/metabolism ; Intracellular Signaling Peptides and Proteins ; Neuroinflammatory Diseases ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Pyroptosis/physiology
Czasopismo naukowe
Tytuł:
USP22 overexpression fails to augment tumor formation in MMTV-ERBB2 mice but loss of function impacts MMTV promoter activity.
Autorzy:
Kuang, Xianghong (AUTHOR)
Salinger, Andrew (AUTHOR)
Benavides, Fernando (AUTHOR)
Muller, William J. (AUTHOR)
Dent, Sharon Y. R. (AUTHOR)
Koutelou, Evangelia (AUTHOR)
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Źródło:
PLoS ONE. 1/18/2024, Vol. 19 Issue 1, p1-19. 19p.
Czasopismo naukowe
Tytuł:
USP29 activation mediated by FUBP1 promotes AURKB stability and oncogenic functions in gastric cancer.
Autorzy:
Tu, Rongfu (AUTHOR)
Kang, Ye (AUTHOR)
Pan, Yiwen (AUTHOR)
Da, Yanyan (AUTHOR)
Ren, Doudou (AUTHOR)
Zhang, Ru (AUTHOR)
Cai, Zeqiong (AUTHOR)
Liu, Yijia (AUTHOR)
Xu, Jiao (AUTHOR)
Ma, Junpeng (AUTHOR)
Zhou, Zhiyong (AUTHOR)
Yin, Shupeng (AUTHOR)
Li, Xiaozhuang (AUTHOR)
Zhang, Peng (AUTHOR)
Zhang, Qi (AUTHOR)
Wang, Jingchao (AUTHOR)
Lu, Xinlan (AUTHOR)
Zhang, Chengsheng (AUTHOR)
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Źródło:
Cancer Cell International. 1/17/2024, Vol. 24 Issue 1, p1-14. 14p.
Czasopismo naukowe
Tytuł:
Non-canonical regulation of the reactivation of an oncogenic herpesvirus by the OTUD4-USP7 deubiquitinases.
Autorzy:
Wang, Shaowei (AUTHOR)
Tian, Xuezhang (AUTHOR)
Zhou, Yaru (AUTHOR)
Xie, Jun (AUTHOR)
Gao, Ming (AUTHOR)
Zhong, Yunhong (AUTHOR)
Zhang, Chuchu (AUTHOR)
Yu, Keying (AUTHOR)
Bai, Lei (AUTHOR)
Qin, Qingsong (AUTHOR)
Zhong, Bo (AUTHOR)
Lin, Dandan (AUTHOR)
Feng, Pinghui (AUTHOR)
Lan, Ke (AUTHOR)
Zhang, Junjie (AUTHOR)
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Źródło:
PLoS Pathogens. 1/12/2024, Vol. 20 Issue 1, p1-25. 25p.
Czasopismo naukowe
Tytuł:
A novel missense variant in OTUD5 causes X‐linked multiple congenital anomalies‐neurodevelopmental syndrome.
Autorzy:
Tian, Weifang (AUTHOR)
Li, Haiyu (AUTHOR)
Li, Ying (AUTHOR)
Guo, Jing (AUTHOR)
Wang, Handuo (AUTHOR)
Yang, Bo (AUTHOR)
Li, Pengyun (AUTHOR)
Cui, Xueyin (AUTHOR)
Liu, Ling (AUTHOR)
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Źródło:
Molecular Genetics & Genomic Medicine. Jan2024, Vol. 12 Issue 1, p1-10. 10p.
Czasopismo naukowe
Tytuł:
Targeting reversible post-translational modifications with PROTACs: a focus on enzymes modifying protein lysine and arginine residues.
Autorzy:
Pichlak, Marta (AUTHOR)
Sobierajski, Tomasz (AUTHOR)
Błażewska, Katarzyna M. (AUTHOR)
Gendaszewska-Darmach, Edyta (AUTHOR)
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Źródło:
Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2023, Vol. 38 Issue 1, p1-37. 37p.
Czasopismo naukowe
Tytuł:
The Correlations between the Intensity of Histopathological Ubiquitin-Specific Protease 11 Staining and Progression of Prostate Cancer.
Autorzy:
Kim, Jae Heon (AUTHOR)
Yang, Hee Jo (AUTHOR)
Lee, Kwang Woo (AUTHOR)
Park, Jae Joon (AUTHOR)
Lee, Chang-Ho (AUTHOR)
Jeon, Youn Soo (AUTHOR)
Kim, Jae Ho (AUTHOR)
Park, Suyeon (AUTHOR)
Song, Su Jung (AUTHOR)
Lee, Ji-Hye (AUTHOR)
Moon, Ahrim (AUTHOR)
Kim, Yon Hee (AUTHOR)
Song, Yun Seob (AUTHOR)
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Źródło:
Pharmaceuticals (14248247). Dec2023, Vol. 16 Issue 12, p1703. 13p.
Czasopismo naukowe
Tytuł:
Targeting USP8 Inhibits O‐GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGT.
Autorzy:
Tang, Jianing (AUTHOR)
Long, Guo (AUTHOR)
Hu, Kuan (AUTHOR)
Xiao, Desheng (AUTHOR)
Liu, Shuang (AUTHOR)
Xiao, Liang (AUTHOR)
Zhou, Ledu (AUTHOR)
Tao, Yongguang (AUTHOR)
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Źródło:
Advanced Science. 11/24/2023, Vol. 10 Issue 33, p1-16. 16p.
Czasopismo naukowe
Tytuł:
Targeting ubiquitin specific proteases (USPs) in cancer immunotherapy: from basic research to preclinical application.
Autorzy:
Gao, Hongli (AUTHOR)
Yin, Jianqiao (AUTHOR)
Ji, Ce (AUTHOR)
Yu, Xiaopeng (AUTHOR)
Xue, Jinqi (AUTHOR)
Guan, Xin (AUTHOR)
Zhang, Shuang (AUTHOR)
Liu, Xun (AUTHOR)
Xing, Fei (AUTHOR)
Pokaż więcej
Źródło:
Journal of Experimental & Clinical Cancer Research (17569966). 11/21/2023, Vol. 42 Issue 1, p1-22. 22p.
Czasopismo naukowe

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