Temat: "myeloid derived suppressor cells" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Monocytic myeloid-derived suppressor cells as an immune indicator of early diagnosis and prognosis in patients with sepsis.
Autorzy:: Cui J; Department of Infectious Diseases, The First Affiliated Hospital of Soochow University, No. 899 Pinghai Road, Gusu District, 215006, Suzhou, China.
Cai W; Department of Infectious Diseases, The First Affiliated Hospital of Soochow University, No. 899 Pinghai Road, Gusu District, 215006, Suzhou, China.
Lin J; Department of Infectious Diseases, The First Affiliated Hospital of Soochow University, No. 899 Pinghai Road, Gusu District, 215006, Suzhou, China.
Zhang L; Center of Clinical Laboratory, The First Affiliated Hospital of Soochow University, No. 899 Pinghai Road, Gusu District, 215006, Suzhou, China.
Miao Y; Department of Infectious Diseases, The Third Affiliated Hospital of Nantong University, No. 60 Qingnian Middle Road, Chongchuan District, 226006, Nantong, China.
Xu Y; Department of Infectious Diseases, The First Affiliated Hospital of Soochow University, No. 899 Pinghai Road, Gusu District, 215006, Suzhou, China.
Zhao W; Department of Infectious Diseases, The First Affiliated Hospital of Soochow University, No. 899 Pinghai Road, Gusu District, 215006, Suzhou, China. .; Pokaż więcej
Źródło:: BMC infectious diseases [BMC Infect Dis] 2024 Apr 13; Vol. 24 (1), pp. 399. Date of Electronic Publication: 2024 Apr 13.
Typ publikacji:: Journal Article
MeSH Terms:: Myeloid-Derived Suppressor Cells*
Sepsis*/diagnosis
Humans ; Leukocytes, Mononuclear ; Prognosis ; Inpatients ; Early Diagnosis ; C-Reactive Protein ; Procalcitonin ; Biomarkers

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Skocz do pozycji: 2.

Tytuł:: The Influence of Myeloid-Derived Suppressor Cell Expansion in Neuroinflammation and Neurodegenerative Diseases.
Autorzy:: Tamberi L; Department of Clinical and Molecular Sciences (DISCLIMO), Polytechnic University of Marche, 60121 Ancona, Italy.
Belloni A; Department of Clinical and Molecular Sciences (DISCLIMO), Polytechnic University of Marche, 60121 Ancona, Italy.
Pugnaloni A; Department of Clinical and Molecular Sciences (DISCLIMO), Polytechnic University of Marche, 60121 Ancona, Italy.
Rippo MR; Department of Clinical and Molecular Sciences (DISCLIMO), Polytechnic University of Marche, 60121 Ancona, Italy.
Olivieri F; Department of Clinical and Molecular Sciences (DISCLIMO), Polytechnic University of Marche, 60121 Ancona, Italy.; Clinic of Laboratory and Precision Medicine, National Institute of Health and Sciences on Ageing (IRCCS INRCA), 60124 Ancona, Italy.
Procopio AD; Department of Clinical and Molecular Sciences (DISCLIMO), Polytechnic University of Marche, 60121 Ancona, Italy.; Clinic of Laboratory and Precision Medicine, National Institute of Health and Sciences on Ageing (IRCCS INRCA), 60124 Ancona, Italy.
Bronte G; Department of Clinical and Molecular Sciences (DISCLIMO), Polytechnic University of Marche, 60121 Ancona, Italy.; Clinic of Laboratory and Precision Medicine, National Institute of Health and Sciences on Ageing (IRCCS INRCA), 60124 Ancona, Italy.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Apr 06; Vol. 13 (7). Date of Electronic Publication: 2024 Apr 06.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Myeloid-Derived Suppressor Cells*/pathology
Neurodegenerative Diseases*/pathology
Humans ; Neuroinflammatory Diseases ; Inflammation/pathology ; Cell Proliferation

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Skocz do pozycji: 3.

Tytuł:: Obesity correlates with the immunosuppressive ILC2s-MDSCs axis in advanced breast cancer.
Autorzy:: Liu W; School of Public Health, Xinjiang Medical University, Urumqi, People's Republic of China.; Department of Mammary Medicine, Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi, People's Republic of China.; Department of Internal Medicine, the Third Clinical College of Xinjiang Medical University, Urumqi, People's Republic of China.; Xinjiang Uygur Autonomous Region Cancer Center/Xinjiang Key Laboratory of Oncology, Urumqi, People's Republic of China.; Xinjiang Key Laboratory of Molecular Biology for Endemic Diseases, Urumqi, Xinjiang, People's Republic of China.; Key Laboratory of Oncology of Xinjiang Uyghur Autonomous Region, Urumqi, Xinjiang, People's Republic of China.
Li B; Department of Mammary Medicine, Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi, People's Republic of China.; Department of Internal Medicine, the Third Clinical College of Xinjiang Medical University, Urumqi, People's Republic of China.; Xinjiang Uygur Autonomous Region Cancer Center/Xinjiang Key Laboratory of Oncology, Urumqi, People's Republic of China.
Liu D; Department of Mammary Medicine, Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi, People's Republic of China.; Department of Internal Medicine, the Third Clinical College of Xinjiang Medical University, Urumqi, People's Republic of China.; Xinjiang Uygur Autonomous Region Cancer Center/Xinjiang Key Laboratory of Oncology, Urumqi, People's Republic of China.
Zhao B; Department of Mammary Medicine, Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi, People's Republic of China.; Department of Internal Medicine, the Third Clinical College of Xinjiang Medical University, Urumqi, People's Republic of China.; Xinjiang Uygur Autonomous Region Cancer Center/Xinjiang Key Laboratory of Oncology, Urumqi, People's Republic of China.
Sun G; Xinjiang Uygur Autonomous Region Cancer Center/Xinjiang Key Laboratory of Oncology, Urumqi, People's Republic of China.; Department of Breast and Thyroid Surgery, Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People's Republic of China.
Ding J; Xinjiang Key Laboratory of Molecular Biology for Endemic Diseases, Urumqi, Xinjiang, People's Republic of China.; Department of Immunology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi, Xinjiang, People's Republic of China.; Pokaż więcej
Źródło:: Immunity, inflammation and disease [Immun Inflamm Dis] 2024 Mar; Vol. 12 (3), pp. e1196.
Typ publikacji:: Journal Article
MeSH Terms:: Myeloid-Derived Suppressor Cells*/metabolism
Triple Negative Breast Neoplasms*/metabolism
Humans ; Immunity, Innate ; B7-H1 Antigen/metabolism ; Interleukin-17/metabolism ; Interleukin-5/metabolism ; Lymphocytes/metabolism ; Cytokines/metabolism

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Skocz do pozycji: 4.

Tytuł:: Carbon Ion Irradiation Activates Anti-Cancer Immunity.
Autorzy:: Sudo M; Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Japan.
Tsutsui H; Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Japan.
Fujimoto J; Department of Gastroenterological Surgery, Hyogo Medical University, Nishinomiya 663-8501, Japan.; Osaka Heavy Ion Therapy Center, Osaka 540-0008, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 29; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 29.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Neoplasms*/pathology
Myeloid-Derived Suppressor Cells*
Heavy Ion Radiotherapy*
Humans ; T-Lymphocytes, Regulatory ; DNA ; Tumor Microenvironment

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Skocz do pozycji: 5.

Tytuł:: Pivotal role of myeloid-derived suppressor cells in infection-related tumor growth.
Autorzy:: Ito N; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Tsujimoto H; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Miyazaki H; Division of Biomedical Engineering, Research Institute, National Defense Medical College, Tokorozawa, Japan.
Takahata R; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.
Ueno H; Department of Surgery, National Defense Medical College, Tokorozawa, Japan.; Pokaż więcej
Źródło:: Cancer medicine [Cancer Med] 2024 Feb; Vol. 13 (4), pp. e6917.
Typ publikacji:: Journal Article
MeSH Terms:: Myeloid-Derived Suppressor Cells*
Neoplasms*
Humans ; Animals ; Mice ; B7-H1 Antigen

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Skocz do pozycji: 6.

Tytuł:: Mitochondria-mediated ferroptosis induced by CARD9 ablation prevents MDSCs-dependent antifungal immunity.
Autorzy:: Zhang Z; Department of Endodontic, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Research Institute of Stomatology, Nanjing University, Nanjing, 210008, China.; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.
Li P; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.
Chen Y; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.
Chen Y; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.
Wang X; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.
Shen S; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.
Zhao Y; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China.
Zhu Y; Department of Endodontic, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Research Institute of Stomatology, Nanjing University, Nanjing, 210008, China. .
Wang T; The State Key Laboratory of Pharmaceutical Biotechnology, Chemistry and Biomedicine Innovation Center (ChemBIC), Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China. .; Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing, 210093, China. .; Pokaż więcej
Źródło:: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Apr 02; Vol. 22 (1), pp. 210. Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:: Journal Article
MeSH Terms:: Myeloid-Derived Suppressor Cells*
Ferroptosis*
Candidiasis*
Acute Kidney Injury*
Mice ; Animals ; Antifungal Agents ; Mice, Knockout
SCR Disease Name:: Systemic candidiasis

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Skocz do pozycji: 7.

Tytuł:: Cisplatin-induced oxPAPC release enhances MDSCs infiltration into LL2 tumour tissues through MCP-1/CCL2 and LTB4/LTB4R pathways.
Autorzy:: Nie J; Department of Biotherapy, Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; Department of Pulmonary and Critical Care Medicine, The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.
Ai J; Department of Biotherapy, Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Hong W; Department of Biotherapy, Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Bai Z; Department of Biotherapy, Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Wang B; Department of Biotherapy, Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yang J; Department of Biotherapy, Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Zhang Z; Department of Biotherapy, Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Mo F; Department of Biotherapy, Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yang J; Department of Biotherapy, Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Sun Q; Department of Biotherapy, Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; West China Medical Publishers, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Wei X; Department of Biotherapy, Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, China.; Pokaż więcej
Źródło:: Cell proliferation [Cell Prolif] 2024 Apr; Vol. 57 (4), pp. e13570. Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:: Journal Article
MeSH Terms:: Myeloid-Derived Suppressor Cells*
Lung Neoplasms*/drug therapy
Phosphatidylcholines*
Animals ; Mice ; Cisplatin/pharmacology ; Leukotriene B4 ; Tumor Microenvironment

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Skocz do pozycji: 8.

Tytuł:: Bladder-cancer-derived exosomal circRNA_0013936 promotes suppressive immunity by up-regulating fatty acid transporter protein 2 and down-regulating receptor-interacting protein kinase 3 in PMN-MDSCs.
Autorzy:: Shi X; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Pang S; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Zhou J; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Yan G; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Gao R; Southern Medical University, Guangzhou, China.
Wu H; Southern Medical University, Guangzhou, China.
Wang Z; Southern Medical University, Guangzhou, China.
Wei Y; Southern Medical University, Guangzhou, China.
Liu X; Southern Medical University, Guangzhou, China.
Tan W; Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. .; Pokaż więcej
Źródło:: Molecular cancer [Mol Cancer] 2024 Mar 09; Vol. 23 (1), pp. 52. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: MicroRNAs*/genetics
MicroRNAs*/metabolism
Myeloid-Derived Suppressor Cells*/metabolism
RNA, Circular*/genetics
RNA, Circular*/metabolism
Urinary Bladder Neoplasms*/pathology
Humans ; CD8-Positive T-Lymphocytes/metabolism ; Fatty Acids/metabolism ; Protein Kinases/metabolism ; Urinary Bladder/metabolism ; Exosomes/genetics ; Coenzyme A Ligases/genetics ; Coenzyme A Ligases/metabolism ; Receptor-Interacting Protein Serine-Threonine Kinases/genetics ; Receptor-Interacting Protein Serine-Threonine Kinases/metabolism

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Skocz do pozycji: 9.

Tytuł:: Myeloid-Derived Suppressor Cells: Therapeutic Target for Gastrointestinal Cancers.
Autorzy:: Arshad J; University of Arizona Cancer Center, GI Medical Oncology, Tucson, AZ 85724, USA.
Rao A; Banner University Medical Center-University of Arizona, Tucson, AZ 85719, USA.
Repp ML; College of Medicine, University of Arizona, Tucson, AZ 85719, USA.
Rao R; University Hospitals Cleveland Medical Center, Case Western Reserve School of Medicine, Cleveland, OH 44106, USA.
Wu C; Banner University Medical Center-University of Arizona, Tucson, AZ 85719, USA.
Merchant JL; Division of Gastroenterology and Hepatology, Department of Medicine, University of Arizona College of Medicine, Tucson, AZ 85724, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 04; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Myeloid-Derived Suppressor Cells*/metabolism
Gastrointestinal Neoplasms*/metabolism
Humans ; Myeloid Cells ; Immunotherapy ; Tumor Microenvironment

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Skocz do pozycji: 10.

Tytuł:: FFAR2 expressing myeloid-derived suppressor cells drive cancer immunoevasion.
Autorzy:: Zhao Z; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Qin J; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Qian Y; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Huang C; Fujian Provincial Hospital, Fuzhou, China.
Liu X; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Wang N; Huzhou Central Hospital, Affiliated Hospital of Zhejiang University, Zhejiang, China.
Li L; Huzhou Central Hospital, Affiliated Hospital of Zhejiang University, Zhejiang, China.
Chao Y; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Tan B; BRL Medicine Inc., Shanghai, China.
Zhang N; BRL Medicine Inc., Shanghai, China.
Qian M; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Li D; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Liu M; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China.
Du B; Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology and School of Life Sciences, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, China. .; Pokaż więcej
Źródło:: Journal of hematology & oncology [J Hematol Oncol] 2024 Feb 24; Vol. 17 (1), pp. 9. Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Myeloid-Derived Suppressor Cells*
Neoplasms*
Adenocarcinoma of Lung*/metabolism
Humans ; Mice ; Animals ; Calcium/metabolism ; Peroxisome Proliferator-Activated Receptors/metabolism ; Arginine/metabolism ; Acetates/metabolism ; Tumor Microenvironment

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Skocz do pozycji: 11.

Tytuł:: From glioma gloom to immune bloom: unveiling novel immunotherapeutic paradigms-a review.
Autorzy:: Regmi M; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China.; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China.; Peking University Health Science Center, Beijing, 100191, China.; Henan Academy of Innovations in Medical Science (AIMS), Zhengzhou, 450003, China.
Wang Y; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China.; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China.
Liu W; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China.; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China.; Peking University Health Science Center, Beijing, 100191, China.
Dai Y; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China.; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China.; Peking University Health Science Center, Beijing, 100191, China.
Liu S; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China.; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China.; Peking University Health Science Center, Beijing, 100191, China.
Ma K; Peking University Health Science Center, Beijing, 100191, China.
Lin G; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China.; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China.
Yang J; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China.; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China.
Liu H; Henan Academy of Innovations in Medical Science (AIMS), Zhengzhou, 450003, China.; National Engineering Research Center for Ophthalmology, Beijing, 100730, China.; Engineering Research Center of Ophthalmic Equipment and Materials, Ministry of Education, Beijing, 100730, China.; Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing, 100730, China.
Wu J; Henan Academy of Innovations in Medical Science (AIMS), Zhengzhou, 450003, China. .; National Engineering Research Center for Ophthalmology, Beijing, 100730, China. .; Engineering Research Center of Ophthalmic Equipment and Materials, Ministry of Education, Beijing, 100730, China. .; Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing, 100730, China. .
Yang C; Department of Neurosurgery, Peking University Third Hospital, Peking University, Beijing, 100191, China. .; Center for Precision Neurosurgery and Oncology of Peking University Health Science Center, Peking University, Beijing, 100191, China. .; Henan Academy of Innovations in Medical Science (AIMS), Zhengzhou, 450003, China. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Feb 12; Vol. 43 (1), pp. 47. Date of Electronic Publication: 2024 Feb 12.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Glioma*/pathology
Glioblastoma*/pathology
Myeloid-Derived Suppressor Cells*
Brain Neoplasms*/drug therapy
Humans ; Immunotherapy ; Immunomodulation ; Tumor Microenvironment

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Skocz do pozycji: 12.

Tytuł:: Myeloid-Derived Suppressor-like Cells as a Prognostic Marker in Critically Ill Patients: Insights from Experimental Endotoxemia and Intensive Care Patients.
Autorzy:: Schrijver IT; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Herderschee J; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Théroude C; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Kritikos A; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Leijte G; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.; Department of Intensive Care Medicine, Radboud University Medical Center, 6525 EP Nijmegen, The Netherlands.
Le Roy D; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Brochut M; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Chiche JD; Service of Adult Intensive Care Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Perreau M; Service of Immunology and Allergy, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1010 Lausanne, Switzerland.
Pantaleo G; Service of Immunology and Allergy, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1010 Lausanne, Switzerland.
Guery B; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.
Kox M; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.; Department of Intensive Care Medicine, Radboud University Medical Center, 6525 EP Nijmegen, The Netherlands.
Pickkers P; Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.; Department of Intensive Care Medicine, Radboud University Medical Center, 6525 EP Nijmegen, The Netherlands.
Calandra T; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.; Service of Immunology and Allergy, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1010 Lausanne, Switzerland.
Roger T; Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, 1011 Lausanne, Switzerland.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Feb 08; Vol. 13 (4). Date of Electronic Publication: 2024 Feb 08.
Typ publikacji:: Journal Article
MeSH Terms:: Endotoxemia*
Myeloid-Derived Suppressor Cells*
Humans ; Critical Illness ; Prognosis ; Critical Care ; Endotoxins

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Skocz do pozycji: 13.

Tytuł:: Mesenchymal Stem/Stromal Cells Induce Myeloid-Derived Suppressor Cells in the Bone Marrow via the Activation of the c-Jun N-Terminal Kinase Signaling Pathway.
Autorzy:: Lee HJ; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea.
Oh JY; Laboratory of Ocular Regenerative Medicine and Immunology, Biomedical Research Institute, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea.; Department of Ophthalmology, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 17; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:: Journal Article
MeSH Terms:: Myeloid-Derived Suppressor Cells*
Mesenchymal Stem Cells*
JNK Mitogen-Activated Protein Kinases ; Bone Marrow ; Interleukin-10 ; Signal Transduction

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Skocz do pozycji: 14.

Tytuł:: The Functional Roles of MDSCs in Severe COVID-19 Pathogenesis.
Autorzy:: Len JS; School of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore.
Koh CWT; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore.
Chan KR; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore.; Pokaż więcej
Źródło:: Viruses [Viruses] 2023 Dec 23; Vol. 16 (1). Date of Electronic Publication: 2023 Dec 23.
Typ publikacji:: Journal Article; Review
MeSH Terms:: COVID-19*
Myeloid-Derived Suppressor Cells*
Aged ; Humans ; Post-Acute COVID-19 Syndrome ; Gene Expression Profiling ; Immunocompromised Host

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Skocz do pozycji: 15.

Tytuł:: Myeloid-derived suppressor cells inhibit natural killer cells in myelodysplastic syndromes through the TIGIT/CD155 pathway.
Autorzy:: Yue J; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Li J; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Ma J; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Zhai Y; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Shen L; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Zhang W; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Li L; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Fu R; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.; Pokaż więcej
Źródło:: Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 2166333.
Typ publikacji:: Journal Article
MeSH Terms:: Myeloid-Derived Suppressor Cells*/metabolism
Myelodysplastic Syndromes*/metabolism
Humans ; Granzymes/metabolism ; Granzymes/pharmacology ; Perforin/metabolism ; Perforin/pharmacology ; NK Cell Lectin-Like Receptor Subfamily K/metabolism ; Killer Cells, Natural ; Cytokines ; Receptors, Immunologic/metabolism

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Skocz do pozycji: 16.

Tytuł:: Oncogenic PIK3CA recruits myeloid-derived suppressor cells to shape the immunosuppressive tumour microenvironment in luminal breast cancer through the 5-lipoxygenase-dependent arachidonic acid pathway.
Autorzy:: Li X; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.; Department of Thyroid and Neck, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China.
Chen G; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
Wang F; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
Guo X; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.; Department of Breast Pathology and Lab, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.
Zhang R; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
Liu P; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
Dong L; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.
Yu W; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.
Wang H; College of Life Sciences, Nankai University, Tianjin, China.
Wang H; Laboratory of Cancer Cell Biology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Caner, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.
Yu J; Cancer Molecular Diagnostics Core, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China.; Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China.; Pokaż więcej
Źródło:: Clinical and translational medicine [Clin Transl Med] 2023 Nov; Vol. 13 (11), pp. e1483.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Breast Neoplasms*/metabolism
Myeloid-Derived Suppressor Cells*
Female ; Humans ; Arachidonate 5-Lipoxygenase/genetics ; Arachidonate 5-Lipoxygenase/metabolism ; Arachidonic Acid/metabolism ; Class I Phosphatidylinositol 3-Kinases/genetics ; Class I Phosphatidylinositol 3-Kinases/metabolism ; Immunosuppressive Agents ; Leukotriene B4/metabolism ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Tumor Microenvironment

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Skocz do pozycji: 17.

Tytuł:: Targeting PMN-MDSCs via CD300ld receptor for cancer immunotherapy.
Autorzy:: Li Y; Institute of Pediatrics of Children's Hospital of Fudan University, Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; The Fifth People's Hospital of Shanghai, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Wang C; State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Lu Z; The Fifth People's Hospital of Shanghai, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
Luo M; Institute of Pediatrics of Children's Hospital of Fudan University, Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Pokaż więcej
Źródło:: Clinical and translational medicine [Clin Transl Med] 2024 Jan; Vol. 14 (1), pp. e1534.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Myeloid-Derived Suppressor Cells*
Neoplasms*/therapy
Humans ; Immunotherapy

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Skocz do pozycji: 18.

Tytuł:: Targeting the myeloid microenvironment in neuroblastoma.
Autorzy:: Stip MC; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
Teeuwen L; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
Dierselhuis MP; Princess Máxima Center for Pediatric Oncology, 3584 CS, Utrecht, The Netherlands.
Leusen JHW; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands.
Krijgsman D; Center for Translational Immunology, University Medical Center Utrecht, 3584 CX, Utrecht, The Netherlands. .; Center for Molecular Medicine, University Medical Center Utrecht, 3584 CX, Utrecht, the Netherlands. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Dec 13; Vol. 42 (1), pp. 337. Date of Electronic Publication: 2023 Dec 13.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Neuroblastoma*/genetics
Neoplasms*/therapy
Myeloid-Derived Suppressor Cells*
Humans ; Myeloid Cells ; Immunotherapy ; Macrophages ; Tumor Microenvironment

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Skocz do pozycji: 19.

Tytuł:: Immunosuppressive Activity of Exosomes from Granulocytic Myeloid-Derived Suppressor Cells in a Murine Model of Immune Bone Marrow Failure.
Autorzy:: Manley AL; Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Chen J; Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Fitzgerald W; Intracellular Interactions, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Feng X; Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Young NS; Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Sep 28; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 28.
Typ publikacji:: Journal Article
MeSH Terms:: Myeloid-Derived Suppressor Cells*
Exosomes*
MicroRNAs*/genetics
Pancytopenia*
Mice ; Animals ; CD8-Positive T-Lymphocytes ; Disease Models, Animal ; Granulocytes ; Immunosuppressive Agents/pharmacology ; Bone Marrow Failure Disorders

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Skocz do pozycji: 20.

Tytuł:: Identification and validation of Birc5 as a novel activated cell cycle program biomarker associated with infiltration of immunosuppressive myeloid-derived suppressor cells in hepatocellular carcinoma.
Autorzy:: Liu Y; Department of Radiation Oncology, Anhui Provincial Cancer Hospital, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Chen X; Department of Gastrointestinal Oncology Surgery, Anhui Provincial Cancer Hospital, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Luo W; Department of Pathology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Zhao Y; Department of Radiation Oncology, Anhui Provincial Cancer Hospital, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Nashan B; Organ Transplant Center, Department of Hepatobiliary and Transplantation Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Huang L; Department of Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Medical Center on Aging of Ruijin Hospital, MCARJH, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Yuan X; Organ Transplant Center, Department of Hepatobiliary and Transplantation Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.; Pokaż więcej
Źródło:: Cancer medicine [Cancer Med] 2023 Aug; Vol. 12 (15), pp. 16370-16385. Date of Electronic Publication: 2023 Jun 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carcinoma, Hepatocellular*/metabolism
Myeloid-Derived Suppressor Cells*
Liver Neoplasms*/metabolism
Animals ; Humans ; Leukocytes, Mononuclear/metabolism ; Cell Division ; Biomarkers/metabolism ; Tumor Microenvironment/genetics

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