Temat: "proteolysis" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Systematic identification of 20S proteasome substrates.
Autorzy:: Pepelnjak M; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland.
Rogawski R; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 7610001, Israel.
Arkind G; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 7610001, Israel.
Leushkin Y; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 7610001, Israel.
Fainer I; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 7610001, Israel.
Ben-Nissan G; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 7610001, Israel.
Picotti P; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland. .
Sharon M; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 7610001, Israel. .; Pokaż więcej
Źródło:: Molecular systems biology [Mol Syst Biol] 2024 Apr; Vol. 20 (4), pp. 403-427. Date of Electronic Publication: 2024 Jan 29.
Typ publikacji:: Journal Article
MeSH Terms:: Proteasome Endopeptidase Complex*/metabolism
Proteins*/metabolism
Proteolysis

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Skocz do pozycji: 2.

Tytuł:: Acceleration of Protein Degradation by 20S Proteasome-Binding Peptides Generated by In Vitro Artificial Evolution.
Autorzy:: Zhu Y; Graduate School of Bioscience, Nagahama Institute of Bio-Science and Technology, 1266 Tamura-cho, Nagahama 526-0829, Japan.
Shigeyoshi K; Graduate School of Bioscience, Nagahama Institute of Bio-Science and Technology, 1266 Tamura-cho, Nagahama 526-0829, Japan.
Hayakawa Y; Graduate School of Bioscience, Nagahama Institute of Bio-Science and Technology, 1266 Tamura-cho, Nagahama 526-0829, Japan.
Fujiwara S; Graduate School of Bioscience, Nagahama Institute of Bio-Science and Technology, 1266 Tamura-cho, Nagahama 526-0829, Japan.
Kishida M; Modality Research Laboratories, Biologics Division, Daiichi Sankyo Co., Ltd., 1-2-58, Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan.
Ohki H; Modality Research Laboratories, Biologics Division, Daiichi Sankyo Co., Ltd., 1-2-58, Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan.
Horibe T; Graduate School of Bioscience, Nagahama Institute of Bio-Science and Technology, 1266 Tamura-cho, Nagahama 526-0829, Japan.
Shionyu M; Graduate School of Bioscience, Nagahama Institute of Bio-Science and Technology, 1266 Tamura-cho, Nagahama 526-0829, Japan.
Mizukami T; Graduate School of Bioscience, Nagahama Institute of Bio-Science and Technology, 1266 Tamura-cho, Nagahama 526-0829, Japan.; Frontier Pharma Inc., 1281-8 Tamura, Nagahama 526-0829, Japan.
Hasegawa M; Graduate School of Bioscience, Nagahama Institute of Bio-Science and Technology, 1266 Tamura-cho, Nagahama 526-0829, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 14; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:: Journal Article
MeSH Terms:: Proteasome Endopeptidase Complex*/metabolism
Proteins*/metabolism
Proteolysis ; Peptides/metabolism ; Acceleration

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Skocz do pozycji: 3.

Tytuł:: Predicting Structural Susceptibility of Proteins to Proteolytic Processing.
Autorzy:: Matveev EV; Skolkovo Institute of Science and Technology, Moscow 121205, Russia.; A.A. Kharkevich Institute for Information Transmission Problems, Moscow 127051, Russia.; Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow 117998, Russia.
Safronov VV; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow 119991, Russia.
Ponomarev GV; Skolkovo Institute of Science and Technology, Moscow 121205, Russia.; A.A. Kharkevich Institute for Information Transmission Problems, Moscow 127051, Russia.
Kazanov MD; Skolkovo Institute of Science and Technology, Moscow 121205, Russia.; A.A. Kharkevich Institute for Information Transmission Problems, Moscow 127051, Russia.; Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow 117998, Russia.; Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul 34956, Turkey.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 28; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 28.
Typ publikacji:: Journal Article
MeSH Terms:: Proteins*/chemistry
Peptide Hydrolases*/metabolism
Proteolysis ; Protein Processing, Post-Translational ; Protein Structure, Secondary ; Substrate Specificity

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Skocz do pozycji: 4.

Tytuł:: Emerging Strategies in Proteolysis-Targeting Chimeras (PROTACs): Highlights from 2022.
Autorzy:: Tamatam R; College of Pharmacy, Gachon University, 191 Hambakmoe-ro, Yeonsu-gu, Incheon 21936, Republic of Korea.; Gachon Pharmaceutical Research Institute, Gachon University, 191 Hambakmoe-ro, Yeonsu-gu, Incheon 21936, Republic of Korea.
Shin D; College of Pharmacy, Gachon University, 191 Hambakmoe-ro, Yeonsu-gu, Incheon 21936, Republic of Korea.; Gachon Pharmaceutical Research Institute, Gachon University, 191 Hambakmoe-ro, Yeonsu-gu, Incheon 21936, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 08; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 08.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Proteins*/chemistry
Neoplasms*
Humans ; Proteolysis ; Ubiquitin-Protein Ligases/metabolism

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Skocz do pozycji: 5.

Tytuł:: Targeted Protein Degradation: Clinical Advances in the Field of Oncology.
Autorzy:: Salama AKAA; Department of Pharmacology, Center of Physiology and Pharmacology & Comprehensive Cancer Center (CCC), Medical University of Vienna, 1090 Vienna, Austria.
Trkulja MV; Department of Pharmacology, Center of Physiology and Pharmacology & Comprehensive Cancer Center (CCC), Medical University of Vienna, 1090 Vienna, Austria.
Casanova E; Department of Pharmacology, Center of Physiology and Pharmacology & Comprehensive Cancer Center (CCC), Medical University of Vienna, 1090 Vienna, Austria.
Uras IZ; Department of Pharmacology, Center of Physiology and Pharmacology & Comprehensive Cancer Center (CCC), Medical University of Vienna, 1090 Vienna, Austria.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Dec 06; Vol. 23 (23). Date of Electronic Publication: 2022 Dec 06.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Medical Oncology*
Proteins*
Proteolysis

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Skocz do pozycji: 6.

Tytuł:: Proteolysis-targeting chimaeras (PROTACs) as pharmacological tools and therapeutic agents: advances and future challenges.
Autorzy:: Wang C; The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao Cancer Institute, Qingdao, China.
Zhang Y; The Affiliated Cardiovascular Hospital of Qingdao University, Qingdao University, Qingdao, China.; School of Pharmacy, Qingdao University, Qingdao, China.
Zhang T; The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao Cancer Institute, Qingdao, China.
Shi L; The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao Cancer Institute, Qingdao, China.
Geng Z; The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao Cancer Institute, Qingdao, China.
Xing D; The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao Cancer Institute, Qingdao, China.; School of Life Sciences, Tsinghua University, Beijing, China.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 1667-1693.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Proteins*/metabolism
Ubiquitin-Protein Ligases*/metabolism
Intercellular Signaling Peptides and Proteins ; Ligands ; Proteolysis

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Skocz do pozycji: 7.

Tytuł:: Protein-Protein Interaction Prediction for Targeted Protein Degradation.
Autorzy:: Orasch O; Celeris Therapeutics GmbH, Salzamtsgasse 7, 8010 Graz, Austria.
Weber N; Celeris Therapeutics GmbH, Salzamtsgasse 7, 8010 Graz, Austria.
Müller M; Celeris Therapeutics GmbH, Salzamtsgasse 7, 8010 Graz, Austria.
Amanzadi A; Celeris Therapeutics GmbH, Salzamtsgasse 7, 8010 Graz, Austria.
Gasbarri C; Celeris Therapeutics GmbH, Salzamtsgasse 7, 8010 Graz, Austria.
Trummer C; Celeris Therapeutics GmbH, Salzamtsgasse 7, 8010 Graz, Austria.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Jun 24; Vol. 23 (13). Date of Electronic Publication: 2022 Jun 24.
Typ publikacji:: Journal Article
MeSH Terms:: Protein Interaction Mapping*/methods
Proteins*/metabolism
Computational Biology/methods ; Machine Learning ; Proteolysis

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Skocz do pozycji: 8.

Tytuł:: The Molecular Mechanisms Governing the Assembly of the Immuno- and Thymoproteasomes in the Presence of Constitutive Proteasomes.
Autorzy:: Watanabe A; Laboratory of Protein Metabolism, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 1130033, Japan.
Yashiroda H; Laboratory of Protein Metabolism, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 1130033, Japan.
Ishihara S; Laboratory of Protein Metabolism, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 1130033, Japan.
Lo M; Laboratory of Protein Metabolism, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 1130033, Japan.
Murata S; Laboratory of Protein Metabolism, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 1130033, Japan.; Pokaż więcej
Źródło:: Cells [Cells] 2022 May 07; Vol. 11 (9). Date of Electronic Publication: 2022 May 07.
Typ publikacji:: Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:: Proteasome Endopeptidase Complex*/metabolism
Proteins*/metabolism
Animals ; Catalytic Domain ; Cytoplasm/metabolism ; Proteolysis

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Skocz do pozycji: 9.

Tytuł:: The Potential of Proteolytic Chimeras as Pharmacological Tools and Therapeutic Agents.
Autorzy:: Coll-Martínez B; Molecular Biology Institute of Barcelona (IBMB), Spanish National Research Council (CSIC), Barcelona Science Park, 08028 Barcelona, Spain.; IQS School of Engineering, Universidad Ramon Llull, Via Augusta 390, 08017 Barcelona, Spain.
Delgado A; Research Unit on Bioactive Molecules (RUBAM), Department of Biological Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Jordi Girona 18-26, 08034 Barcelona, Spain.; Unit of Pharmaceutical Chemistry (Associated Unit to CSIC), Department of Pharmacology, Toxicology and Medicinal Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona (UB), Avda. Joan XXIII 27-31, 08028 Barcelona, Spain.
Crosas B; Molecular Biology Institute of Barcelona (IBMB), Spanish National Research Council (CSIC), Barcelona Science Park, 08028 Barcelona, Spain.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2020 Dec 16; Vol. 25 (24). Date of Electronic Publication: 2020 Dec 16.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Proteolysis*/drug effects
Proteolysis*/radiation effects
Proteins/*metabolism
Allosteric Regulation/drug effects ; Autophagy/drug effects ; Drug Discovery ; Humans ; Light ; Proteasome Endopeptidase Complex/metabolism ; Proteins/antagonists & inhibitors ; Small Molecule Libraries/chemistry ; Small Molecule Libraries/pharmacology ; Ubiquitin-Protein Ligases/metabolism

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Skocz do pozycji: 10.

Tytuł:: The UFM1 Pathway Impacts HCMV US2-Mediated Degradation of HLA Class I.
Autorzy:: Schuren ABC; Department of Medical Microbiology, University Medical Center Utrecht, Postbus 85500, 3508 GA Utrecht, The Netherlands.
Boer IGJ; Department of Medical Microbiology, University Medical Center Utrecht, Postbus 85500, 3508 GA Utrecht, The Netherlands.
Bouma EM; Department of Medical Microbiology, University Medical Center Utrecht, Postbus 85500, 3508 GA Utrecht, The Netherlands.; Department of Medical Microbiology, University Medical Center Groningen, Postbus 30001, 9700 RB Groningen, The Netherlands.
Van de Weijer ML; Department of Medical Microbiology, University Medical Center Utrecht, Postbus 85500, 3508 GA Utrecht, The Netherlands.; Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK.
Costa AI; Department of Medical Microbiology, University Medical Center Utrecht, Postbus 85500, 3508 GA Utrecht, The Netherlands.
Hubel P; Innate Immunity Laboratory, Max-Planck Institute for Biochemistry, Am Klopferspitz 18, Martinsried, D-82152 Munich, Germany.; Core Facility Hohenheim, Universität Hohenheim, Emil-Wolff-Straße 12, 70599 Stuttgart, Germany.
Pichlmair A; Innate Immunity Laboratory, Max-Planck Institute for Biochemistry, Am Klopferspitz 18, Martinsried, D-82152 Munich, Germany.; School of Medicine, Institute of Virology, Technical University of Munich, Schneckenburgerstr 8, D-81675 Munich, Germany.; German Center for Infection Research (DZIF), Munich Partner Site, D-85764 Neuherberg, Germany.
Lebbink RJ; Department of Medical Microbiology, University Medical Center Utrecht, Postbus 85500, 3508 GA Utrecht, The Netherlands.
Wiertz EJHJ; Department of Medical Microbiology, University Medical Center Utrecht, Postbus 85500, 3508 GA Utrecht, The Netherlands.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Jan 08; Vol. 26 (2). Date of Electronic Publication: 2021 Jan 08.
Typ publikacji:: Journal Article
MeSH Terms:: Endoplasmic Reticulum-Associated Degradation*
Proteolysis*
CD8-Positive T-Lymphocytes/*metabolism
Cytomegalovirus/*metabolism
HLA Antigens/*metabolism
Proteins/*metabolism
Viral Envelope Proteins/*metabolism
CD8-Positive T-Lymphocytes/virology ; Cytomegalovirus/genetics ; HLA Antigens/genetics ; Humans ; Proteins/genetics ; U937 Cells

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Skocz do pozycji: 11.

Tytuł:: Nonspecific cleavages arising from reconstitution of trypsin under mildly acidic conditions.
Autorzy:: Niu B; Analytical Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, MD, United States of America.
Martinelli Ii M; Analytical Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, MD, United States of America.
Jiao Y; Analytical Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, MD, United States of America.
Wang C; Analytical Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, MD, United States of America.
Cao M; Analytical Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, MD, United States of America.
Wang J; Analytical Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, MD, United States of America.
Meinke E; Analytical Sciences, BioPharmaceuticals Development, R&D, AstraZeneca, Gaithersburg, MD, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Jul 28; Vol. 15 (7), pp. e0236740. Date of Electronic Publication: 2020 Jul 28 (Print Publication: 2020).
Typ publikacji:: Journal Article
MeSH Terms:: Proteolysis*
Acids/*chemistry
Peptide Fragments/*metabolism
Proteins/*metabolism
Proteomics/*methods
Trypsin/*metabolism
Humans ; Peptide Fragments/analysis ; Peptide Fragments/isolation & purification

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Skocz do pozycji: 12.

Tytuł:: Concept and application of circulating proteasomes.
Autorzy:: Choi WH; BK21 FOUR Biomedical Science Program, Seoul National University College of Medicine, Seoul, 03080, Korea.; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, 03080, Korea.
Kim S; BK21 FOUR Biomedical Science Program, Seoul National University College of Medicine, Seoul, 03080, Korea.; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, 03080, Korea.; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, 03080, Korea.
Park S; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, 03080, Korea.
Lee MJ; BK21 FOUR Biomedical Science Program, Seoul National University College of Medicine, Seoul, 03080, Korea. .; Department of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul, 03080, Korea. .; Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, 03080, Korea. .; Pokaż więcej
Źródło:: Experimental & molecular medicine [Exp Mol Med] 2021 Oct; Vol. 53 (10), pp. 1539-1546. Date of Electronic Publication: 2021 Oct 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Proteasome Endopeptidase Complex*/metabolism
Proteins*/metabolism
Eukaryotic Cells ; Humans ; Proteolysis

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Skocz do pozycji: 13.

Tytuł:: A comparative study of synthetic winged peptides for absolute protein quantification.
Autorzy:: Benesova E; Faculty of Science, Masaryk University, RECETOX, Kamenice 753/5, Pavilion D29, 625 00, Brno, Czech Republic.
Vidova V; Faculty of Science, Masaryk University, RECETOX, Kamenice 753/5, Pavilion D29, 625 00, Brno, Czech Republic.
Spacil Z; Faculty of Science, Masaryk University, RECETOX, Kamenice 753/5, Pavilion D29, 625 00, Brno, Czech Republic. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 May 25; Vol. 11 (1), pp. 10880. Date of Electronic Publication: 2021 May 25.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Biological Assay/*methods
Peptides/*chemistry
Proteins/*analysis
Amino Acid Sequence ; Biological Assay/standards ; Humans ; Isotope Labeling ; Kinetics ; Peptides/chemical synthesis ; Protein Conformation ; Proteins/chemistry ; Proteolysis ; Proteomics/methods ; Reference Standards ; Solubility ; Solvents ; Trypsin/metabolism

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Skocz do pozycji: 14.

Tytuł:: Monoclonal Antibody Aggregation Associated with Free Radical Induced Oxidation.
Autorzy:: Zheng K; Pharmaceutical Development, Genentech, South San Francisco, CA 94080, USA.
Ren D; Oceanside Pharmaceutical Technical Development, Genentech, Oceanside, CA 92056, USA.
Wang YJ; Pharmaceutical Development, Genentech, South San Francisco, CA 94080, USA.
Lilyestrom W; Pharmaceutical Development, Genentech, South San Francisco, CA 94080, USA.
Scherer T; Pharmaceutical Development, Genentech, South San Francisco, CA 94080, USA.
Hong JKY; Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, MI 48109, USA.
Ji JA; Pharmaceutical Development, Genentech, South San Francisco, CA 94080, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Apr 12; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 12.
Typ publikacji:: Journal Article
MeSH Terms:: Antibodies, Monoclonal/*chemistry
Oxidative Stress/*genetics
Proteins/*chemistry
Proteolysis/*drug effects
Amidines ; Antibodies, Monoclonal/genetics ; Dimerization ; Free Radicals/chemistry ; Free Radicals/metabolism ; Humans ; Oxidants/chemistry ; Oxidants/pharmacology ; Oxidation-Reduction/drug effects ; Protein Aggregates/genetics ; Proteins/genetics ; Proteins/therapeutic use ; Tryptophan/chemistry ; Tryptophan/genetics

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Skocz do pozycji: 15.

Tytuł:: Cellular Control of Protein Turnover via the Modification of the Amino Terminus.
Autorzy:: Winter N; Max Perutz Labs, Department of Biochemistry and Cell Biology, University of Vienna, A-1030 Vienna, Austria.
Novatchkova M; Vienna BioCenter, Research Institute of Molecular Pathology, A-1030 Vienna, Austria.; Vienna BioCenter, Institute of Molecular Biotechnology, A-1030 Vienna, Austria.
Bachmair A; Max Perutz Labs, Department of Biochemistry and Cell Biology, University of Vienna, A-1030 Vienna, Austria.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Mar 29; Vol. 22 (7). Date of Electronic Publication: 2021 Mar 29.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Methionyl Aminopeptidases/*metabolism
Proteins/*metabolism
Ribosomes/*metabolism
Bacterial Proteins/metabolism ; Caspases/metabolism ; Endopeptidases/metabolism ; Endoplasmic Reticulum ; Humans ; Protein Sorting Signals ; Proteins/chemistry ; Proteolysis ; Ubiquitin-Protein Ligases/metabolism

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Skocz do pozycji: 16.

Tytuł:: HDXmodeller: an online webserver for high-resolution HDX-MS with auto-validation.
Autorzy:: Salmas RE; Department of Chemistry, Britannia House, King's College London, SE1 1DB, London, UK.
Borysik AJ; Department of Chemistry, Britannia House, King's College London, SE1 1DB, London, UK. .; Pokaż więcej
Źródło:: Communications biology [Commun Biol] 2021 Feb 15; Vol. 4 (1), pp. 199. Date of Electronic Publication: 2021 Feb 15.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hydrogen Deuterium Exchange-Mass Spectrometry*
Internet*
Proteins/*metabolism
Animals ; Automation, Laboratory ; High-Throughput Nucleotide Sequencing ; Humans ; Protein Binding ; Protein Folding ; Proteins/chemistry ; Proteolysis ; Reproducibility of Results

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Skocz do pozycji: 17.

Tytuł:: The Diverse Calpain Family in Trypanosomatidae: Functional Proteins Devoid of Proteolytic Activity?
Autorzy:: Ennes-Vidal V; Laboratório de Estudos Integrados em Protozoologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (FIOCRUZ), 21040-360 Rio de Janeiro, Brazil.
Branquinha MH; Laboratório de Estudos Avançados de Microrganismos Emergentes e Resistentes, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro (UFRJ), 21941-901 Rio de Janeiro, Brazil.
Dos Santos ALS; Laboratório de Estudos Avançados de Microrganismos Emergentes e Resistentes, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro (UFRJ), 21941-901 Rio de Janeiro, Brazil.; Programa de Pós-Graduação em Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro (UFRJ), 21941-909 Rio de Janeiro, Brazil.
d'Avila-Levy CM; Laboratório de Estudos Integrados em Protozoologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz (FIOCRUZ), 21040-360 Rio de Janeiro, Brazil.; Pokaż więcej
Źródło:: Cells [Cells] 2021 Feb 01; Vol. 10 (2). Date of Electronic Publication: 2021 Feb 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Calpain/*metabolism
Gene Expression/*genetics
Proteins/*metabolism
Animals ; Humans ; Proteolysis ; Trypanosomatina

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Skocz do pozycji: 18.

Tytuł:: Proteomic analysis of the hypothalamus of broiler-type Taiwan country chickens in response to acute heat stress.
Autorzy:: Tu WL; Department of Animal Science, National Chung Hsing University, Taichung, Taiwan.
Cheng CY; Department of Animal Science, National Chung Hsing University, Taichung, Taiwan.
Chen CJ; Proteomics Core Laboratory, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan.
Chan HL; Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu, Taiwan.; Department of Medical Sciences, National Tsing Hua University, Hsinchu, Taiwan.
Wang SH; Department of Animal Science, National Chung Hsing University, Taichung, Taiwan.
Tang PC; Department of Animal Science, National Chung Hsing University, Taichung, Taiwan.; Agricultural Biotechnology Center, National Chung Hsing University, Taichung, Taiwan.; Center for the Integrative and Evolutionary Galliformes Genomics, iEGG Center, National Chung Hsing University, Taichung, Taiwan.
Chen CF; Department of Animal Science, National Chung Hsing University, Taichung, Taiwan.; Agricultural Biotechnology Center, National Chung Hsing University, Taichung, Taiwan.; Center for the Integrative and Evolutionary Galliformes Genomics, iEGG Center, National Chung Hsing University, Taichung, Taiwan.
Chen HH; Department of Animal Science, National Chung Hsing University, Taichung, Taiwan.
Lee YP; Department of Animal Science, National Chung Hsing University, Taichung, Taiwan.
Chen SE; Department of Animal Science, National Chung Hsing University, Taichung, Taiwan.; Agricultural Biotechnology Center, National Chung Hsing University, Taichung, Taiwan.; Center for the Integrative and Evolutionary Galliformes Genomics, iEGG Center, National Chung Hsing University, Taichung, Taiwan.
Huang SY; Department of Animal Science, National Chung Hsing University, Taichung, Taiwan.; Agricultural Biotechnology Center, National Chung Hsing University, Taichung, Taiwan.; Center for the Integrative and Evolutionary Galliformes Genomics, iEGG Center, National Chung Hsing University, Taichung, Taiwan.; Research Center for Sustainable Energy and Nanotechnology, National Chung Hsing University, Taichung, Taiwan.; Pokaż więcej
Źródło:: Animal science journal = Nihon chikusan Gakkaiho [Anim Sci J] 2018 Oct; Vol. 89 (10), pp. 1475-1485. Date of Electronic Publication: 2018 Aug 20.
Typ publikacji:: Journal Article
MeSH Terms:: Proteolysis*
Body Temperature Regulation/*physiology
Chickens/*metabolism
Chickens/*physiology
Hot Temperature/*adverse effects
Hypothalamus/*metabolism
Hypothalamus/*physiology
Proteins/*chemistry
Proteins/*metabolism
Proteomics/*methods
Stress, Physiological/*physiology
Animals ; Cytoskeleton/metabolism ; Female ; Oxidative Stress ; Protein Folding ; Proteins/physiology ; Taiwan ; Time Factors

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Skocz do pozycji: 19.

Tytuł:: Emerging branches of the N-end rule pathways are revealing the sequence complexities of N-termini dependent protein degradation.
Autorzy:: Eldeeb MA; a Department of Biochemistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.; b Department of Chemistry, Faculty of Science, Cairo University, Giza, Cairo, Egypt.
Leitao LCA; a Department of Biochemistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.
Fahlman RP; a Department of Biochemistry, University of Alberta, Edmonton, AB T6G 2H7, Canada.; c Department of Oncology, University of Alberta, Edmonton, AB T6G 2H7, Canada.; Pokaż więcej
Źródło:: Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2018 Jun; Vol. 96 (3), pp. 289-294. Date of Electronic Publication: 2017 Dec 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Proteolysis*
Amino Acids/*metabolism
Protein Processing, Post-Translational/*physiology
Proteins/*metabolism
Amino Acid Sequence ; Humans ; Substrate Specificity/physiology

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Skocz do pozycji: 20.

Tytuł:: Crosstalk and ultrasensitivity in protein degradation pathways.
Autorzy:: Mallela A; Department of Mathematics, University of California Davis, Davis, California, United States of America.
Nariya MK; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America.
Deeds EJ; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, California, United States of America.; Institute for Quantitative and Computational Biosciences, University of California, Los Angeles, Los Angeles, California, United States of America.; Pokaż więcej
Źródło:: PLoS computational biology [PLoS Comput Biol] 2020 Dec 28; Vol. 16 (12), pp. e1008492. Date of Electronic Publication: 2020 Dec 28 (Print Publication: 2020).
Typ publikacji:: Journal Article
MeSH Terms:: Proteins/*chemistry
Catalysis ; Humans ; Protein Processing, Post-Translational ; Proteolysis ; Ubiquitin-Protein Ligases/metabolism

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