Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Ukraiński (UK)
Przejdź do strony domowej biblioteki Uniwersytet Ekonomiczny we Wrocławiu Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaUniwersytet Ekonomiczny we Wrocławiu

Wyszukujesz frazę ""rho-Associated Kinases"" wg kryterium: Temat

  Lista filtrów
Wyrównaj
Wyświetlanie 1-20 z 231
Tytuł:
Sovesudil (locally acting rho kinase inhibitor) for the treatment of normal-tension glaucoma: the randomized phase II study.
Autorzy:
Ha A; Department of Medicine, Seoul National University College of Medicine, Seoul, Korea.; Department of Ophthalmology, Jeju National University Hospital, Jeju-si, Korea.
Kim YK; Department of Medicine, Seoul National University College of Medicine, Seoul, Korea.; Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.
Jeoung JW; Department of Medicine, Seoul National University College of Medicine, Seoul, Korea.; Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.
Satyal S; pH-Pharma Co., Ltd, Seoul, Korea.
Kim J; pH-Pharma Co., Ltd, Seoul, Korea.
Kim S; pH-Pharma Co., Ltd, Seoul, Korea.
Park KH; Department of Medicine, Seoul National University College of Medicine, Seoul, Korea.; Department of Ophthalmology, Seoul National University Hospital, Seoul, Korea.
Pokaż więcej
Źródło:
Acta ophthalmologica [Acta Ophthalmol] 2022 Mar; Vol. 100 (2), pp. e470-e477. Date of Electronic Publication: 2021 Jul 28.
Typ publikacji:
Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
MeSH Terms:
Intraocular Pressure*/drug effects
Low Tension Glaucoma*/drug therapy
rho-Associated Kinases*/antagonists & inhibitors
rho-Associated Kinases*/therapeutic use
Aged ; Female ; Humans ; Male ; Middle Aged ; Dose-Response Relationship, Drug ; Double-Blind Method ; Ocular Hypertension
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Design, synthesis, and biological evaluation of urea-based ROCK2 inhibitors.
Autorzy:
Wang L; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation Yantai University, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, China.
Qi J; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation Yantai University, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, China.
Fan M; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation Yantai University, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, China.
Yao L; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation Yantai University, Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, China.
Pokaż więcej
Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2021 Dec; Vol. 98 (6), pp. 969-978. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Kinase Inhibitors/*chemistry
Protein Kinase Inhibitors/*pharmacology
Urea/*chemistry
rho-Associated Kinases/*antagonists & inhibitors
Drug Design ; Drug Evaluation, Preclinical ; Enzyme-Linked Immunosorbent Assay ; Molecular Docking Simulation ; Molecular Structure ; Protein Kinase Inhibitors/chemical synthesis ; Structure-Activity Relationship ; rho-Associated Kinases/chemistry ; rho-Associated Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Rho-associated coiled-coil kinase 1 activation mediates amyloid precursor protein site-specific Ser655 phosphorylation and triggers amyloid pathology.
Autorzy:
Hu YB; Department of Neurology, Neuroscience Institute, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ren RJ; Department of Neurology, Neuroscience Institute, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhang YF; Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Huang Y; National Clinical Research Centre for Neurological Diseases, Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing, China.; Faculty of Medicine, Neuroscience Research Australia, UNSW Australia, Sydney, New South Wales, Australia.
Cui HL; Department of Neurology, Neuroscience Institute, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ma C; Department of Human Anatomy, Histology and Embryology, Institute of Basic Medical Sciences, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Qiu WY; Department of Human Anatomy, Histology and Embryology, Institute of Basic Medical Sciences, Neuroscience Center, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Wang H; Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Cui PJ; Department of Geriatrics, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chen HZ; Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Institute of Interdisciplinary Science, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wang G; Department of Neurology, Neuroscience Institute, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Pokaż więcej
Źródło:
Aging cell [Aging Cell] 2019 Oct; Vol. 18 (5), pp. e13001. Date of Electronic Publication: 2019 Jul 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alzheimer Disease/*metabolism
Alzheimer Disease/*pathology
Amyloid beta-Peptides/*metabolism
Amyloid beta-Protein Precursor/*chemistry
Amyloid beta-Protein Precursor/*metabolism
Phosphoserine/*metabolism
rho-Associated Kinases/*metabolism
Alzheimer Disease/drug therapy ; Amides/pharmacology ; Amyloid beta-Peptides/antagonists & inhibitors ; Animals ; Cells, Cultured ; HEK293 Cells ; Humans ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Phosphorylation/drug effects ; Protein Kinase Inhibitors/pharmacology ; Pyridines/pharmacology ; RNA, Small Interfering/pharmacology ; rho-Associated Kinases/antagonists & inhibitors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The early days of a blood vessel.
Autorzy:
Nilsson H; Department of Physiology, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.
Pokaż więcej
Źródło:
Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2018 Jul; Vol. 223 (3), pp. e13082. Date of Electronic Publication: 2018 May 14.
Typ publikacji:
Editorial; Comment
MeSH Terms:
Calcium*
rho-Associated Kinases*
Animals ; Arteries ; Rats
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Acrolein, an endogenous aldehyde induces synaptic dysfunction in vitro and in vivo: Involvement of RhoA/ROCK2 pathway.
Autorzy:
Zhu Z; School of Medicine, Sun Yat-Sen University, Guangzhou, China.; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
Lu J; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.; Department of Internal Medicine, The Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou, China.
Wang S; School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Peng W; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
Yang Y; School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Chen C; School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, China.
Zhou X; Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Yang X; Key Laboratory of Modern Toxicology of Shenzhen, Center for Disease Control and Prevention.
Xin W; Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Chen X; School of Pharmaceutical Sciences, South China Research Center for Acupuncture and Moxibustion, Guangzhou University of Chinese Medicine, Guangzhou, China.
Pi J; Guangzhou Foreign Language School, Guangzhou, China.
Yin W; Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Yao L; Research Institute of Acupuncture and Moxibustion, Shandong University of Traditional Chinese Medicine, Jinan, China.
Pi R; School of Medicine, Sun Yat-Sen University, Guangzhou, China.; International Joint Laboratory of Novel Anti-Dementia Drugs of Guangzhou, Guangzhou, China.; Guangdong Province Key Laboratory of Brain Function and Disease, Sun Yat-sen University, Guangzhou, China.
Pokaż więcej
Źródło:
Aging cell [Aging Cell] 2022 Apr; Vol. 21 (4), pp. e13587. Date of Electronic Publication: 2022 Mar 22.
Typ publikacji:
Journal Article
MeSH Terms:
Acrolein*/adverse effects
Acrolein*/metabolism
Alzheimer Disease*/pathology
Aldehydes/metabolism ; Animals ; Disease Models, Animal ; Hippocampus/metabolism ; Humans ; Mice ; rho-Associated Kinases/metabolism ; rhoA GTP-Binding Protein/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Design and development of novel fasudil derivatives as potent antibreast cancer agent that improves intestinal flora and intestinal barrier function in rats.
Autorzy:
Liang J; Oncology Radiotherapy Department, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Tang M; Department of Breast Surgery, Jiangxi Provincial Cancer Hospital, Nanchang, Jiangxi, China.
Wang L; Department of Breast Surgery, Jiangxi Provincial Cancer Hospital, Nanchang, Jiangxi, China.
Huang R; Department of Clinical Laboratory, Jiangxi Provincial Cancer Hospital, Nanchang, Jiangxi, China.
Fu A; Department of Pathology, Jiangxi Provincial Cancer Hospital, Nanchang, Jiangxi, China.
Zhou J; Oncology Radiotherapy Department, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Pokaż więcej
Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2021 Dec; Vol. 98 (6), pp. 1065-1078. Date of Electronic Publication: 2021 Oct 11.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*chemistry
Antineoplastic Agents/*pharmacology
Breast Neoplasms/*drug therapy
Gastrointestinal Microbiome/*drug effects
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine/analogs & derivatives ; Animals ; Antineoplastic Agents/chemical synthesis ; Breast Neoplasms/chemically induced ; Breast Neoplasms/pathology ; Colon/drug effects ; Colon/metabolism ; Drug Screening Assays, Antitumor ; Female ; Humans ; Lipid Peroxidation/drug effects ; MCF-7 Cells ; Mammary Neoplasms, Experimental/chemically induced ; Mammary Neoplasms, Experimental/drug therapy ; Mammary Neoplasms, Experimental/pathology ; Rats, Sprague-Dawley ; Thiazoles/chemistry ; rho-Associated Kinases/antagonists & inhibitors ; rho-Associated Kinases/genetics ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson-Gilford progeria syndrome.
Autorzy:
Kang HT; Well Aging Research Center, Samsung Advanced Institute of Technology, Samsung Electronics, Suwon-si, Korea.
Park JT; Well Aging Research Center, Samsung Advanced Institute of Technology, Samsung Electronics, Suwon-si, Korea.
Choi K; Well Aging Research Center, Samsung Advanced Institute of Technology, Samsung Electronics, Suwon-si, Korea.
Choi HJC; Well Aging Research Center, Samsung Advanced Institute of Technology, Samsung Electronics, Suwon-si, Korea.
Jung CW; Well Aging Research Center, Samsung Advanced Institute of Technology, Samsung Electronics, Suwon-si, Korea.
Kim GR; Well Aging Research Center, DGIST, Daegu, Korea.
Lee YS; Well Aging Research Center, DGIST, Daegu, Korea.; Department of New Biology, DGIST, Daegu, Korea.
Park SC; Well Aging Research Center, DGIST, Daegu, Korea.; Department of New Biology, DGIST, Daegu, Korea.
Pokaż więcej
Źródło:
Aging cell [Aging Cell] 2017 Jun; Vol. 16 (3), pp. 541-550. Date of Electronic Publication: 2017 Mar 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amides/*pharmacology
Mitochondria/*drug effects
Progeria/*metabolism
Protein Kinase Inhibitors/*pharmacology
Pyridines/*pharmacology
Reactive Oxygen Species/*antagonists & inhibitors
rac1 GTP-Binding Protein/*genetics
rho-Associated Kinases/*antagonists & inhibitors
Amino Acid Sequence ; Cells, Cultured ; Cytochromes c/genetics ; Cytochromes c/metabolism ; DNA Breaks, Double-Stranded/drug effects ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Gene Expression Regulation ; HEK293 Cells ; High-Throughput Screening Assays ; Humans ; Mitochondria/metabolism ; Mitochondria/pathology ; Phosphorylation ; Progeria/genetics ; Progeria/pathology ; Protein Binding ; Reactive Oxygen Species/metabolism ; Sequence Alignment ; Sequence Homology, Amino Acid ; Signal Transduction ; Two-Hybrid System Techniques ; rac1 GTP-Binding Protein/metabolism ; rho-Associated Kinases/genetics ; rho-Associated Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Oxidative stress, inflammation, and peritoneal dialysis: A molecular biology approach.
Autorzy:
Innico G; Nephrology, Dialysis and Transplantation Unit, Department of Medicine DIMED, University of Padova, Italy.
Gobbi L; Nephrology, Dialysis and Transplantation Unit, Department of Medicine DIMED, University of Padova, Italy.
Bertoldi G; Nephrology, Dialysis and Transplantation Unit, Department of Medicine DIMED, University of Padova, Italy.
Rigato M; Nephrology, Dialysis and Transplantation Unit, Department of Medicine DIMED, University of Padova, Italy.
Basso A; Nephrology, Dialysis and Transplantation Unit, Department of Medicine DIMED, University of Padova, Italy.
Bonfante L; Nephrology, Dialysis and Transplantation Unit, Department of Medicine DIMED, University of Padova, Italy.
Calò LA; Nephrology, Dialysis and Transplantation Unit, Department of Medicine DIMED, University of Padova, Italy.
Pokaż więcej
Źródło:
Artificial organs [Artif Organs] 2021 Oct; Vol. 45 (10), pp. 1202-1207. Date of Electronic Publication: 2021 Jun 15.
Typ publikacji:
Journal Article
MeSH Terms:
Oxidative Stress/*physiology
Peritoneal Dialysis/*methods
Renal Insufficiency, Chronic/*therapy
Adult ; Aged ; Albumins/analysis ; Ferritins/blood ; Humans ; Inflammation ; Interleukin-6/blood ; Male ; Middle Aged ; NADPH Oxidases/metabolism ; Peritoneal Dialysis/adverse effects ; rho-Associated Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
3D Chiral Self‐Assembling Matrixes for Regulating Polarization of Macrophages and Enhance Repair of Myocardial Infarction.
Autorzy:
Yang, Lei (AUTHOR)
Yang, Li (AUTHOR)
Lu, Kongli (AUTHOR)
Su, Nan (AUTHOR)
Li, Xueqin (AUTHOR)
Guo, Shuoxiang (AUTHOR)
Xue, Song (AUTHOR)
Lian, Feng (AUTHOR)
Feng, Chuanliang (AUTHOR)
Pokaż więcej
Źródło:
Advanced Science. 11/14/2023, Vol. 10 Issue 32, p1-13. 13p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Annexin A1 restores Aβ 1-42 -induced blood-brain barrier disruption through the inhibition of RhoA-ROCK signaling pathway.
Autorzy:
Park JC; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 110-799, Korea.
Baik SH; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 110-799, Korea.
Han SH; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 110-799, Korea.
Cho HJ; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 110-799, Korea.
Choi H; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 110-799, Korea.
Kim HJ; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 110-799, Korea.
Choi H; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 110-799, Korea.
Lee W; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 110-799, Korea.
Kim DK; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 110-799, Korea.
Mook-Jung I; Department of Biochemistry and Biomedical Sciences, College of Medicine, Seoul National University, Seoul, 110-799, Korea.
Pokaż więcej
Źródło:
Aging cell [Aging Cell] 2017 Feb; Vol. 16 (1), pp. 149-161. Date of Electronic Publication: 2016 Sep 16.
Typ publikacji:
Journal Article
MeSH Terms:
Amyloid beta-Peptides/*toxicity
Annexin A1/*metabolism
Blood-Brain Barrier/*pathology
Peptide Fragments/*toxicity
Signal Transduction/*drug effects
rho-Associated Kinases/*antagonists & inhibitors
rhoA GTP-Binding Protein/*metabolism
Aged ; Alzheimer Disease/blood ; Alzheimer Disease/pathology ; Animals ; Annexin A1/blood ; Blood-Brain Barrier/drug effects ; Blood-Brain Barrier/metabolism ; Capillaries/drug effects ; Capillaries/metabolism ; Female ; Humans ; Male ; Mice, Transgenic ; Pericytes/drug effects ; Pericytes/metabolism ; Receptors, Formyl Peptide/blood ; Receptors, Lipoxin/blood ; Recombinant Proteins/pharmacology ; Tight Junctions/drug effects ; Tight Junctions/metabolism ; rho-Associated Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Inhibition of Rho-kinase by Fasudil protects dopamine neurons and attenuates inflammatory response in an intranasal lipopolysaccharide-mediated Parkinson's model.
Autorzy:
He Q; Department of Neurology, Shanghai Ninth People's Hospital Affiliated Shanghai Jiaotong University School of Medicine, Shanghai, China.; Institute of Neurology, Huashan Hospital, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.
Li YH; Department of Neurology, Institute of Brain Science, Medical School, Shanxi Datong University, Datong, China.
Guo SS; Institute of Neurology, Huashan Hospital, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.
Wang Y; Institute of Neurology, Huashan Hospital, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.
Lin W; Institute of Neurology, Huashan Hospital, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.
Zhang Q; Institute of Neurology, Huashan Hospital, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.
Wang J; Institute of Neurology, Huashan Hospital, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.
Ma CG; Department of Neurology, Institute of Brain Science, Medical School, Shanxi Datong University, Datong, China.; '2011'Collaborative Innovation Center/Research Center of Neurobiology, Shanxi University of Traditional Chinese Medicine, Taiyuan, China.
Xiao BG; Institute of Neurology, Huashan Hospital, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, China.
Pokaż więcej
Źródło:
The European journal of neuroscience [Eur J Neurosci] 2016 Jan; Vol. 43 (1), pp. 41-52. Date of Electronic Publication: 2015 Dec 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine/*analogs & derivatives
Dopaminergic Neurons/*drug effects
Encephalitis/*enzymology
Encephalitis/*prevention & control
Neuroprotective Agents/*administration & dosage
Parkinsonian Disorders/*complications
rho-Associated Kinases/*antagonists & inhibitors
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine/administration & dosage ; Administration, Intranasal ; Animals ; Dopaminergic Neurons/metabolism ; Encephalitis/etiology ; Female ; Inflammation Mediators/metabolism ; Lipopolysaccharides ; Mice, Inbred C57BL ; Microglia/drug effects ; Microglia/metabolism ; Microglia/physiology ; Motor Activity/drug effects ; NF-kappa B/metabolism ; Olfactory Bulb/drug effects ; Olfactory Bulb/metabolism ; Parkinsonian Disorders/chemically induced ; Signal Transduction/drug effects ; Substantia Nigra/drug effects ; Substantia Nigra/metabolism ; alpha-Synuclein/metabolism ; rho-Associated Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Eosinophil cytolysis on Immunoglobulin G is associated with microtubule formation and suppression of rho‐associated protein kinase signalling.
Autorzy:
Esnault, Stephane (AUTHOR)
Leet, Jonathan P. (AUTHOR)
Johansson, Mats W. (AUTHOR)
Barretto, Karina T. (AUTHOR)
Fichtinger, Paul S. (AUTHOR)
Fogerty, Frances J. (AUTHOR)
Bernau, Ksenija (AUTHOR)
Mathur, Sameer K. (AUTHOR)
Mosher, Deane F. (AUTHOR)
Sandbo, Nathan (AUTHOR)
Jarjour, Nizar N. (AUTHOR)
Pokaż więcej
Źródło:
Clinical & Experimental Allergy. Feb2020, Vol. 50 Issue 2, p198-212. 15p. 1 Color Photograph, 6 Graphs.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of RhoC downregulation on the angiogenesis characteristics of myeloma vascular endothelial cells.
Autorzy:
Zhao, Zhihua (AUTHOR)
Liu, Kai (AUTHOR)
Tian, Xiangyu (AUTHOR)
Sun, Miaomiao (AUTHOR)
Wei, Na (AUTHOR)
Zhu, Xiaoyan (AUTHOR)
Yang, Hongmei (AUTHOR)
Wang, Tong (AUTHOR)
Jiang, Guozhong (AUTHOR)
Chen, Kuisheng (AUTHOR)
Pokaż więcej
Źródło:
Cancer Medicine. Jul2019, Vol. 8 Issue 7, p3502-3510. 9p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MiR-599 regulates LPS-mediated apoptosis and inflammatory responses through the JAK2/STAT3 signalling pathway via targeting ROCK1 in human umbilical vein endothelial cells.
Autorzy:
Wang J; Department of Cardiology, Nursing Department, The First Affiliated Hospital of China Medical University, Shenyang, China.
Du A; Department of Cardiology, The First Affiliated Hospital of China Medical University, Shenyang, China.
Wang H; Department of Cardiology, The First Affiliated Hospital of China Medical University, Shenyang, China.
Li Y; Department of Cardiology, The First Affiliated Hospital of China Medical University, Shenyang, China.
Pokaż więcej
Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2020 Aug; Vol. 47 (8), pp. 1420-1428. Date of Electronic Publication: 2020 Apr 25.
Typ publikacji:
Journal Article
MeSH Terms:
Human Umbilical Vein Endothelial Cells/*drug effects
Janus Kinase 2/*metabolism
Lipopolysaccharides/*pharmacology
MicroRNAs/*genetics
STAT3 Transcription Factor/*metabolism
Signal Transduction/*drug effects
rho-Associated Kinases/*genetics
Human Umbilical Vein Endothelial Cells/cytology ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Inflammation/metabolism ; Inflammation/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of cadmium on Rho GTPases signal transduction during osteoclast differentiation.
Autorzy:
He, Shuangjiang (AUTHOR)
Zhang, Kanglei (AUTHOR)
Cao, Ying (AUTHOR)
Liu, Gang (AUTHOR)
Zou, Hui (AUTHOR)
Song, Ruilong (AUTHOR)
Liu, Zongping (AUTHOR)
Pokaż więcej
Temat:
*Cadmium
Rho GTPases
Osteoclasts
Rho-associated kinases
Cellular signal transduction
Bone marrow cells
Źródło:
Environmental Toxicology. Jul2022, Vol. 37 Issue 7, p1608-1617. 10p.
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 231

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies