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Wyszukujesz frazę ""ENDOTHELINS"" wg kryterium: Temat


Tytuł:
Safety, pharmacokinetics, and pharmacodynamics in healthy Chinese volunteers treated with SC0062, a highly selective endothelin‐A receptor antagonist.
Autorzy:
Liu, Yun (AUTHOR)
Wang, Wei (AUTHOR)
Qian, Hongjie (AUTHOR)
Gui, Yuzhou (AUTHOR)
Wang, Yating (AUTHOR)
Song, Rong (AUTHOR)
Chen, Qian (AUTHOR)
Rowinsky, Eric (AUTHOR)
Wang, Sheng (AUTHOR)
Liang, Xiaoguang (AUTHOR)
Gu, Kaicun (AUTHOR)
Zhou, Bo (AUTHOR)
Zhang, Weiwei (AUTHOR)
Zhang, Liqin (AUTHOR)
Yu, Chen (AUTHOR)
Jia, Jingying (AUTHOR) ‐centerlab.com
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Źródło:
CTS: Clinical & Translational Science. Mar2024, Vol. 17 Issue 3, p1-14. 14p.
Czasopismo naukowe
Tytuł:
The Role of the Endocrine System in the Regulation of Acid-Base Balance by the Kidney and the Progression of Chronic Kidney Disease.
Autorzy:
Nagami GT; Nephrology Section, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA.; Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Kraut JA; Nephrology Section, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA.; Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 19; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Renal Insufficiency, Chronic*/metabolism
Acidosis*/metabolism
Humans ; Acid-Base Equilibrium/physiology ; Bicarbonates/metabolism ; Aldosterone/metabolism ; Angiotensin II/metabolism ; Kidney/metabolism ; Endothelins/metabolism ; Endocrine System/metabolism
Czasopismo naukowe
Tytuł:
Amitriptyline inhibits bronchoconstriction and directly promotes dilatation of the airways.
Autorzy:
Hempel P; Department of Pediatrics, Medical Faculty, RWTH Aachen, University Hospital Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.; Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen, University Hospital Aachen, Aachen, Germany.
Klein V; Department of Pediatrics, Medical Faculty, RWTH Aachen, University Hospital Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.; Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen, University Hospital Aachen, Aachen, Germany.
Michely A; Department of Pediatrics, Medical Faculty, RWTH Aachen, University Hospital Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.; Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen, University Hospital Aachen, Aachen, Germany.
Böll S; Department of Pediatrics, Medical Faculty, RWTH Aachen, University Hospital Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.; Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen, University Hospital Aachen, Aachen, Germany.
Rieg AD; Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen, University Hospital Aachen, Aachen, Germany.; Department of Anaesthesiology, Medical Faculty, RWTH Aachen, University Hospital Aachen, Aachen, Germany.
Spillner J; Department of Thoracic and Cardiovascular Surgery, Medical Faculty, RWTH Aachen, University Hospital Aachen, Aachen, Germany.
Braunschweig T; Institute of Pathology, Medical Faculty, RWTH Aachen, University Hospital Aachen, Aachen, Germany.
von Stillfried S; Institute of Pathology, Medical Faculty, RWTH Aachen, University Hospital Aachen, Aachen, Germany.
Wagner N; Department of Pediatrics, Medical Faculty, RWTH Aachen, University Hospital Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.
Martin C; Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen, University Hospital Aachen, Aachen, Germany.
Tenbrock K; Department of Pediatrics, Medical Faculty, RWTH Aachen, University Hospital Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.
Verjans E; Department of Pediatrics, Medical Faculty, RWTH Aachen, University Hospital Aachen, Pauwelsstraße 30, 52074, Aachen, Germany. .; Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen, University Hospital Aachen, Aachen, Germany. .
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Źródło:
Respiratory research [Respir Res] 2023 Oct 31; Vol. 24 (1), pp. 262. Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
Bronchoconstriction*
Asthma*/drug therapy
Mice ; Rats ; Humans ; Animals ; Guinea Pigs ; Methacholine Chloride/pharmacology ; Amitriptyline/pharmacology ; Amitriptyline/therapeutic use ; Histamine/pharmacology ; Bronchodilator Agents/pharmacology ; Bronchodilator Agents/therapeutic use ; Serotonin/pharmacology ; Serotonin/therapeutic use ; Acetylcholine/pharmacology ; Sympathomimetics/pharmacology ; Sympathomimetics/therapeutic use ; 1-Methyl-3-isobutylxanthine/pharmacology ; 1-Methyl-3-isobutylxanthine/therapeutic use ; Dilatation ; Lung ; Albuterol ; Endothelins/pharmacology ; Endothelins/therapeutic use ; Thromboxanes/pharmacology ; Thromboxanes/therapeutic use
Czasopismo naukowe
Tytuł:
Study of fingolimod, nitric oxide inhibitor, and P-glycoprotein inhibitor in modulating the P-glycoprotein expression via an endothelin-sphingolipid pathway in an animal model of pharmacoresistant epilepsy.
Autorzy:
Garg, Nitika
Joshi, Rupa
Bhatia, Alka
Bansal, Seema
Chakrabarti, Amitava
Prakash, Ajay
Saikia, Biman
Modi, Manish
Medhi, Bikash
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Źródło:
Indian Journal of Pharmacology. Sep/Oct2023, Vol. 55 Issue 5, p307-314. 8p.
Czasopismo naukowe
Tytuł:
Endothelin mediates sex-differences in acclimation to high salt diet in rats.
Autorzy:
Nasci VL; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Almutlaq RN; Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Pollock DM; Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Gohar EY; Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. .
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Źródło:
Biology of sex differences [Biol Sex Differ] 2023 Oct 10; Vol. 14 (1), pp. 70. Date of Electronic Publication: 2023 Oct 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Sodium Chloride*/pharmacology
Sodium Chloride, Dietary*/pharmacology
Rats ; Male ; Female ; Animals ; Rats, Sprague-Dawley ; Receptor, Endothelin B/physiology ; Endothelins ; Sodium/metabolism ; Endothelin-1 ; Diet ; Acclimatization
Czasopismo naukowe
Tytuł:
Endothelin-1 in Health and Disease.
Autorzy:
Banecki KMRM; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK.
Dora KA; Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 10; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 10.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cardiovascular Diseases*/metabolism
COVID-19*/metabolism
Endothelin-1*/metabolism
Chronic Pain*/metabolism
Humans ; Endothelins
Czasopismo naukowe
Tytuł:
Role of TRPC3 in Right Ventricular Dilatation under Chronic Intermittent Hypoxia in 129/SvEv Mice.
Autorzy:
Park DY; Department of Otolaryngology, Ajou University School of Medicine, Suwon 16499, Republic of Korea.
Heo W; Department of Pharmacology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Kang M; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Ahn T; Department of Pharmacology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Kim D; Department of Pharmacology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Choi A; Department of Pharmacology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Birnbaumer L; Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC 27709, USA.; Institute of Biomedical Research (BIOMED), Catholic University of Argentina, Buenos Aires C1107AFF, Argentina.
Cho HJ; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.; The Airway Mucus Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Kim JY; Department of Pharmacology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 10; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 10.
Typ publikacji:
Journal Article
MeSH Terms:
Hypertension, Pulmonary*/complications
Hypertension, Pulmonary*/genetics
Hypertrophy, Right Ventricular*/etiology
Hypertrophy, Right Ventricular*/genetics
Sleep Apnea, Obstructive*/metabolism
Animals ; Mice ; Chronic Disease ; Endothelins ; Hypoxia/complications ; Hypoxia/genetics ; Hypoxia/metabolism ; Mice, 129 Strain ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Endothelin Receptor Antagonists in Kidney Disease.
Autorzy:
Martínez-Díaz, Irene (AUTHOR)
Martos, Nerea (AUTHOR)
Llorens-Cebrià, Carmen (AUTHOR)
Álvarez, Francisco J. (AUTHOR)
Bedard, Patricia W. (AUTHOR)
Vergara, Ander (AUTHOR)
Jacobs-Cachá, Conxita (AUTHOR)
Soler, Maria José (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Feb2023, Vol. 24 Issue 4, p3427. 18p.
Czasopismo naukowe
Tytuł:
Targeting the endothelin axis as a therapeutic strategy for oral cancer metastasis and pain.
Autorzy:
Dang D; Department of Oral and Maxillofacial Surgery, New York University, New York, NY, USA.; Bluestone Center for Clinical Research, New York University, New York, NY, USA.
Ye Y; Department of Oral and Maxillofacial Surgery, New York University, New York, NY, USA.; Bluestone Center for Clinical Research, New York University, New York, NY, USA.
Aouizerat BE; Department of Oral and Maxillofacial Surgery, New York University, New York, NY, USA.; Bluestone Center for Clinical Research, New York University, New York, NY, USA.; Rory Meyers College of Nursing, New York University, New York, NY, USA.
Patel YK; Bluestone Center for Clinical Research, New York University, New York, NY, USA.
Viet DT; Bluestone Center for Clinical Research, New York University, New York, NY, USA.
Chan KC; Division of Oral and Maxillofacial Radiology, Section of Hospital Dentistry, Columbia University Irving Medical Center, New York, NY, USA.
Ono K; Department of Physiology, Kyushu Dental University, Kitakyushu, Japan.
Doan C; Department of Oral and Maxillofacial Surgery, Loma Linda University School of Dentistry, Loma Linda, CA, USA.
Figueroa JD; Department of Basic Sciences, Center for Health Disparities and Molecular Medicine, Loma Linda University School of Medicine, Loma Linda, CA, USA.
Yu G; Rory Meyers College of Nursing, New York University, New York, NY, USA.
Viet CT; Department of Oral and Maxillofacial Surgery, Loma Linda University School of Dentistry, Loma Linda, CA, USA. .
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Źródło:
Scientific reports [Sci Rep] 2020 Nov 30; Vol. 10 (1), pp. 20832. Date of Electronic Publication: 2020 Nov 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Endothelins/*genetics
Mouth Neoplasms/*therapy
Neoplasm Metastasis/*therapy
Adult ; Animals ; Cell Line, Tumor ; Cell Proliferation/genetics ; Endothelins/metabolism ; Endothelins/physiology ; Female ; HeLa Cells ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mouth Neoplasms/metabolism ; Neoplasm Invasiveness/genetics ; Pain/metabolism ; Pain/physiopathology ; Pain Management/methods ; Pyrimidines/pharmacology ; Receptor, Endothelin A/genetics ; Receptor, Endothelin A/metabolism ; Receptor, Endothelin B/genetics ; Receptor, Endothelin B/metabolism ; Sulfonamides/pharmacology
Czasopismo naukowe
Tytuł:
The circadian clock protein PER1 is important in maintaining endothelin axis regulation in Dahl salt-sensitive rats.
Autorzy:
Costello HM; Department of Physiology and Aging, University of Florida, Gainesville, FL 32610, USA.; Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, FL 32610, USA.
Juffre A; Department of Physiology and Aging, University of Florida, Gainesville, FL 32610, USA.; Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, FL 32610, USA.; Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL 32610, USA.
Cheng KY; Department of Physiology and Aging, University of Florida, Gainesville, FL 32610, USA.; Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, FL 32610, USA.
Bratanatawira P; Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, FL 32610, USA.
Crislip GR; Department of Physiology and Aging, University of Florida, Gainesville, FL 32610, USA.; Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, FL 32610, USA.
Zietara A; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.; Department of Molecular Pharmacology and Physiology, University of South Florida, Tampa, FL 33602, USA.
Spires DR; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Staruschenko A; Department of Molecular Pharmacology and Physiology, University of South Florida, Tampa, FL 33602, USA.; James A. Haley Veterans' Hospital, Tampa, FL 33612, USA.
Douma LG; Department of Physiology and Aging, University of Florida, Gainesville, FL 32610, USA.; Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, FL 32610, USA.; Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL 32610, USA.
Gumz ML; Department of Physiology and Aging, University of Florida, Gainesville, FL 32610, USA.; Department of Medicine, Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, FL 32610, USA.; Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL 32610, USA.; Center for Integrative Cardiovascular and Metabolic Diseases, University of Florida, Gainesville, FL 32610, USA.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2023 Mar 01; Vol. 101 (3), pp. 136-146. Date of Electronic Publication: 2022 Nov 30.
Typ publikacji:
Journal Article
MeSH Terms:
Circadian Clocks*/genetics
Hypertension*
Rats ; Mice ; Animals ; Rats, Inbred Dahl ; Endothelins ; Kidney/metabolism ; Endothelin-1/genetics ; Endothelin-1/metabolism ; Transcription Factors/metabolism ; Blood Pressure/physiology ; Period Circadian Proteins/genetics
Czasopismo naukowe
Tytuł:
Endothelins and α-melanocyte-stimulating hormone are increased in plasma of patients treated with UVA1 and psoralen plus UVA.
Autorzy:
Abdel-Naser MB; Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Dessau, Germany.
Seltmann H; Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Dessau, Germany.
Altenburg A; Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Dessau, Germany.
Zouboulis CC; Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Dessau, Germany.
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Źródło:
Photodermatology, photoimmunology & photomedicine [Photodermatol Photoimmunol Photomed] 2022 Nov; Vol. 38 (6), pp. 611-613. Date of Electronic Publication: 2022 May 04.
Typ publikacji:
Letter
MeSH Terms:
alpha-MSH*
Ficusin*
Humans ; Ultraviolet Rays/adverse effects ; Eye ; Endothelins
Opinia redakcyjna
Tytuł:
High Glucose-Induced Cardiomyocyte Damage Involves Interplay between Endothelin ET-1/ET A /ET B Receptor and mTOR Pathway.
Autorzy:
Pandey, Sudhir (AUTHOR)
Madreiter-Sokolowski, Corina T. (AUTHOR)
Mangmool, Supachoke (AUTHOR)
Parichatikanond, Warisara (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Nov2022, Vol. 23 Issue 22, p13816. 16p.
Czasopismo naukowe
Tytuł:
Enhanced Cardiorenal Protective Effects of Combining SGLT2 Inhibition, Endothelin Receptor Antagonism and RAS Blockade in Type 2 Diabetic Mice.
Autorzy:
Vergara, Ander (AUTHOR)
Jacobs-Cacha, Conxita (AUTHOR)
Llorens-Cebria, Carmen (AUTHOR)
Ortiz, Alberto (AUTHOR)
Martinez-Diaz, Irene (AUTHOR)
Martos, Nerea (AUTHOR)
Dominguez-Báez, Pamela (AUTHOR)
Van den Bosch, Mireia Molina (AUTHOR)
Bermejo, Sheila (AUTHOR)
Pieper, Michael Paul (AUTHOR)
Benito, Begoña (AUTHOR)
Soler, Maria Jose (AUTHOR)
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Źródło:
International Journal of Molecular Sciences. Nov2022, Vol. 23 Issue 21, p12823. 23p.
Czasopismo naukowe
Tytuł:
Endothelin XVI.
Autorzy:
Widyantoro B; Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia.
Emoto N; Laboratory of Clinical Pharmaceutical Science, Kobe Pharmaceutical University, 4-19-1 Motoyamakita, Higashinada, Kobe 658-8558, Japan.; Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki, Chuo, Kobe 650-0017, Japan.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2020 Sep; Vol. 98 (9), pp. v-vii. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji:
Editorial; Introductory Journal Article
MeSH Terms:
Endothelins*
Congresses as Topic ; Humans ; Japan
Czasopismo naukowe
Tytuł:
The Sixteenth International Conference on Endothelin (ET-16), Kobe, 2019.
Autorzy:
Widyantoro B; Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Centre Harapan Kita, Jakarta, Indonesia.
Ryanto GRT; Laboratory of Clinical Pharmaceutical Science, Kobe Pharmaceutical University, 4-19-1 Motoyamakita, Higashinada, Kobe 658-8558, Japan.; Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki, Chuo, Kobe 650-0017, Japan.
Emoto N; Laboratory of Clinical Pharmaceutical Science, Kobe Pharmaceutical University, 4-19-1 Motoyamakita, Higashinada, Kobe 658-8558, Japan.; Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki, Chuo, Kobe 650-0017, Japan.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2020 Sep; Vol. 98 (9), pp. viii-xii. Date of Electronic Publication: 2020 Sep 14.
Typ publikacji:
Historical Article; Journal Article
MeSH Terms:
Endothelins/*physiology
Biomedical Research/history ; Congresses as Topic ; Endothelins/history ; History, 20th Century ; History, 21st Century ; Humans ; Japan
Czasopismo naukowe
Tytuł:
Sovateltide (IRL-1620) activates neuronal differentiation and prevents mitochondrial dysfunction in adult mammalian brains following stroke.
Autorzy:
Ranjan AK; Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, 60515, USA. .
Briyal S; Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, 60515, USA.
Gulati A; Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, 60515, USA. .; Pharmazz Inc. Research and Development, Willlowbrook, IL, USA. .
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Źródło:
Scientific reports [Sci Rep] 2020 Jul 29; Vol. 10 (1), pp. 12737. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Endothelins/*administration & dosage
Infarction, Middle Cerebral Artery/*drug therapy
Mitochondria/*metabolism
Neural Stem Cells/*cytology
Peptide Fragments/*administration & dosage
Stroke/*drug therapy
Administration, Intravenous ; Animals ; Antigens, Nuclear/metabolism ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Cell Differentiation/drug effects ; Cell Hypoxia/drug effects ; Disease Models, Animal ; Dynamins/metabolism ; Endothelins/pharmacology ; GTP Phosphohydrolases/metabolism ; Infarction, Middle Cerebral Artery/complications ; Infarction, Middle Cerebral Artery/metabolism ; Male ; Mitochondria/drug effects ; Mitochondrial Dynamics ; Mitochondrial Proteins/metabolism ; Nerve Tissue Proteins/metabolism ; Neural Stem Cells/drug effects ; Peptide Fragments/pharmacology ; Rats ; Stroke/etiology ; Stroke/metabolism
Czasopismo naukowe
Tytuł:
Elucidating essential kinases of endothelin signalling by logic modelling of phosphoproteomics data.
Autorzy:
Schäfer A; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.
Gjerga E; Faculty of Medicine, Joint Research Centre for Computational Biomedicine (JRC-COMBINE), RWTH Aachen University, Aachen, Germany.
Welford RW; Idorsia Pharmaceuticals, Allschwil, Switzerland.
Renz I; Idorsia Pharmaceuticals, Allschwil, Switzerland.
Lehembre F; Idorsia Pharmaceuticals, Allschwil, Switzerland.
Groenen PM; Idorsia Pharmaceuticals, Allschwil, Switzerland.
Saez-Rodriguez J; Faculty of Medicine, Joint Research Centre for Computational Biomedicine (JRC-COMBINE), RWTH Aachen University, Aachen, Germany.; Faculty of Medicine, Institute for Computational Biomedicine, Heidelberg University Hospital, Bioquant, Heidelberg University, Heidelberg, Germany.
Aebersold R; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.; Faculty of Science, University of Zürich, Zürich, Switzerland.
Gstaiger M; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.; Competence Center Personalized Medicine UZH/ETH, Zürich, Switzerland.
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Źródło:
Molecular systems biology [Mol Syst Biol] 2019 Aug; Vol. 15 (8), pp. e8828.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Protein Processing, Post-Translational*
Signal Transduction*
Endothelins/*pharmacology
Melanocytes/*metabolism
Phosphoproteins/*genetics
AMP-Activated Protein Kinases/genetics ; AMP-Activated Protein Kinases/metabolism ; Cell Line, Tumor ; Cell Movement/drug effects ; Endothelins/genetics ; Endothelins/metabolism ; Gene Regulatory Networks ; Humans ; MAP Kinase Kinase 4/genetics ; MAP Kinase Kinase 4/metabolism ; Melanocytes/drug effects ; Melanocytes/pathology ; Phosphoproteins/metabolism ; Phosphorylation ; Protein Kinase C/genetics ; Protein Kinase C/metabolism ; Proteomics/methods ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Receptor, Endothelin B/genetics ; Receptor, Endothelin B/metabolism
Czasopismo naukowe
Tytuł:
Role of endothelial dysfunction in the severity of COVID‑19 infection (Review).
Autorzy:
Kadiyska T; Department of Physiology and Pathophysiology, Medical University, 1413 Sofia, Bulgaria.
Tourtourikov I; Genetic Medico‑Diagnostic Laboratory Genica, 1612 Sofia, Bulgaria.
Dabchev K; Genetic Medico‑Diagnostic Laboratory Genica, 1612 Sofia, Bulgaria.
Cherneva R; University Hospital for Respiratory Diseases St. Sophia, 1413 Sofia, Bulgaria.
Stoynev N; Department of Physiology and Pathophysiology, Medical University, 1413 Sofia, Bulgaria.
Hadjiolova R; Department of Physiology and Pathophysiology, Medical University, 1413 Sofia, Bulgaria.
Mitev V; Genetic Medico‑Diagnostic Laboratory Genica, 1612 Sofia, Bulgaria.
Spandidos DA; Laboratory of Clinical Virology, Medical School, University of Crete, Heraklion 71003, Greece.
Adamaki M; Biomedical Applications Unit, Institute Of Chemical Biology, National Hellenic Research Foundation, 11635 Athens, Greece.
Zoumpourlis V; Biomedical Applications Unit, Institute Of Chemical Biology, National Hellenic Research Foundation, 11635 Athens, Greece.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2022 Nov; Vol. 26 (5). Date of Electronic Publication: 2022 Oct 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
COVID-19*
Vascular Diseases*
Angiotensin II ; Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors ; Collagen ; Endothelial Cells ; Endothelins ; Humans ; Interleukin-6 ; Interleukin-8 ; Nitric Oxide ; Reactive Oxygen Species ; Receptor, Angiotensin, Type 1 ; Receptor, Endothelin A ; Receptors, Angiotensin ; Tumor Necrosis Factor-alpha
Czasopismo naukowe
Tytuł:
Effect of cold stress on ovarian & uterine microcirculation in rats and the role of endothelin system.
Autorzy:
Wang D; Hebei University of Chinese Medicine, No.326, Xinshi South Road, Qiaoxi District, Shijiazhuang, 050091, Hebei Province, China.
Cheng X; Hebei University of Chinese Medicine, No.326, Xinshi South Road, Qiaoxi District, Shijiazhuang, 050091, Hebei Province, China. .
Fang H; Hebei University of Chinese Medicine, No.326, Xinshi South Road, Qiaoxi District, Shijiazhuang, 050091, Hebei Province, China.
Ren Y; Hebei University of Chinese Medicine, No.326, Xinshi South Road, Qiaoxi District, Shijiazhuang, 050091, Hebei Province, China.
Li X; Hebei University of Chinese Medicine, No.326, Xinshi South Road, Qiaoxi District, Shijiazhuang, 050091, Hebei Province, China.
Ren W; Hebei University of Chinese Medicine, No.326, Xinshi South Road, Qiaoxi District, Shijiazhuang, 050091, Hebei Province, China.
Xue B; Hebei University of Chinese Medicine, No.326, Xinshi South Road, Qiaoxi District, Shijiazhuang, 050091, Hebei Province, China.
Yang C; Hebei University of Chinese Medicine, No.326, Xinshi South Road, Qiaoxi District, Shijiazhuang, 050091, Hebei Province, China.
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Źródło:
Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2020 Apr 14; Vol. 18 (1), pp. 29. Date of Electronic Publication: 2020 Apr 14.
Typ publikacji:
Journal Article
MeSH Terms:
Cold-Shock Response/*physiology
Endothelins/*metabolism
Microcirculation/*physiology
Ovary/*blood supply
Uterus/*blood supply
Actins/metabolism ; Animals ; Antigens, CD34/metabolism ; Endothelins/blood ; Estradiol/blood ; Estrous Cycle/physiology ; Female ; Ovary/metabolism ; Progesterone/blood ; Rats, Sprague-Dawley ; Receptors, Endothelin/metabolism ; Testosterone/blood ; Uterus/metabolism
Czasopismo naukowe
Tytuł:
Inhibition of Endothelin system during the postnatal nephrogenic period in the rat. Its relationship with hypertension and renal disease in adulthood.
Autorzy:
Albertoni Borghese MF; Departamento de Ciencias Biológicas, Cátedra de Biología Celular y Molecular, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.; Departamento de Ciencias Biológicas, Cátedra de Biología Celular y Molecular, CONICET, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Ortiz MDC; Departamento de Ciencias Biológicas, Cátedra de Biología Celular y Molecular, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Marinoni RC; Departamento de Ciencias Biológicas, Cátedra de Biología Celular y Molecular, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Oronel LH; Departamento de Ciencias Biológicas, Cátedra de Biología Celular y Molecular, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Palamidessi M; Departamento de Ciencias Biológicas, Cátedra de Biología Celular y Molecular, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Yarza CA; Departamento de Ciencias Biológicas, Cátedra de Biología Celular y Molecular, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Di Siervi N; CONICET, Facultad de Farmacia y Bioquímica, Instituto de Investigaciones Farmacológicas (ININFA), Universidad de Buenos Aires, Buenos Aires, Argentina.
Davio C; Departamento de Farmacología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.; CONICET, Facultad de Farmacia y Bioquímica, Instituto de Investigaciones Farmacológicas (ININFA), Universidad de Buenos Aires, Buenos Aires, Argentina.
Majowicz MP; Departamento de Ciencias Biológicas, Cátedra de Biología Celular y Molecular, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
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Źródło:
PloS one [PLoS One] 2020 Mar 03; Vol. 15 (3), pp. e0229756. Date of Electronic Publication: 2020 Mar 03 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Endothelins/*metabolism
Hypertension/*etiology
Kidney Medulla/*growth & development
Receptors, Endothelin/*metabolism
Signal Transduction/*physiology
Adult ; Animals ; Animals, Newborn ; Aquaporin 2/metabolism ; Blood Pressure/drug effects ; Blood Pressure/physiology ; Disease Models, Animal ; Endothelin Receptor Antagonists/pharmacology ; Endothelins/antagonists & inhibitors ; Epithelial Sodium Channels/metabolism ; Humans ; Hypertension/physiopathology ; Infant, Newborn ; Kidney Medulla/drug effects ; Male ; Rats ; Rats, Sprague-Dawley ; Renal Elimination/drug effects ; Renal Elimination/physiology ; Signal Transduction/drug effects ; Sodium Chloride, Dietary/adverse effects ; Sodium Chloride, Dietary/metabolism ; Vasopressins/metabolism
Czasopismo naukowe
Tytuł:
Endothelin antagonism reduces hemoglobin A1c in patients with pulmonary hypertension.
Autorzy:
Stapel JR; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Speed JS; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Clemmer JS; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS 39216, USA.
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2022 Aug 01; Vol. 100 (8), pp. 828-833. Date of Electronic Publication: 2022 Jun 03.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*/drug therapy
Hypertension, Pulmonary*/drug therapy
Insulin Resistance*
Animals ; Blood Glucose ; Endothelin Receptor Antagonists/therapeutic use ; Endothelins ; Glycated Hemoglobin/analysis ; Hypoglycemic Agents/therapeutic use ; Insulin ; Mice
Czasopismo naukowe
Tytuł:
Relationship between endothelin and nitric oxide pathways in the onset and maintenance of hypertension in children and adolescents.
Autorzy:
Genovesi S; School of Medicine and Surgery, University Milano - Bicocca, Milan, Italy. .; Department of Cardiovascular, Neural, and Metabolic Sciences, S Luca Hospital, IRCCS, Istituto Auxologico Italiano, Milan, Italy. .
Giussani M; Department of Cardiovascular, Neural, and Metabolic Sciences, S Luca Hospital, IRCCS, Istituto Auxologico Italiano, Milan, Italy.
Orlando A; Department of Cardiovascular, Neural, and Metabolic Sciences, S Luca Hospital, IRCCS, Istituto Auxologico Italiano, Milan, Italy.
Lieti G; School of Medicine and Surgery, University Milano - Bicocca, Milan, Italy.
Viazzi F; Department of Internal Medicine, University of Study and IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Parati G; School of Medicine and Surgery, University Milano - Bicocca, Milan, Italy.; Department of Cardiovascular, Neural, and Metabolic Sciences, S Luca Hospital, IRCCS, Istituto Auxologico Italiano, Milan, Italy.
Pokaż więcej
Źródło:
Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2022 Mar; Vol. 37 (3), pp. 537-545. Date of Electronic Publication: 2021 Jun 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Hypertension*/etiology
Nitric Oxide*
Adolescent ; Blood Pressure ; Child ; Endothelin-1 ; Endothelins/physiology ; Humans ; Obesity/complications
Czasopismo naukowe
Tytuł:
Anti-Anginal Efficacy of Zibotentan in the Coronary Slow-Flow Phenomenon.
Autorzy:
Pasupathy, Sivabaskari
Tavella, Rosanna
Zeitz, Christopher
Edwards, Suzanne
Worthley, Matthew
Arstall, Margaret
Beltrame, John F.
Pokaż więcej
Temat:
MICROCIRCULATION disorders
CROSSOVER trials
ANGINA pectoris
INTRAVENOUS therapy
ENDOTHELINS
Źródło:
Journal of Clinical Medicine; Mar2024, Vol. 13 Issue 5, p1337, 9p
Czasopismo naukowe
Tytuł:
Mechanistic insights into the selectivity of bicyclophosphorothionate antagonists for housefly versus rat GABA receptors.
Autorzy:
Zheng, Xiaojiao
Liu, Genyan
Ozoe, Yoshihisa
Ju, Xiu‐Lian
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Temat:
ENDOTHELINS
GABA receptors
HOUSEFLY
COMPARATIVE molecular field analysis
THREONINE
MOLECULAR dynamics
RATS
Źródło:
Pest Management Science; Mar2024, Vol. 80 Issue 3, p1382-1399, 18p
Przedsiębiorstwo/ jednostka:
SOCIETY of Chemical Industry (Great Britain)
Czasopismo naukowe
Tytuł:
TONIC ACTION OF ENDOTHELIN TYPE B AND DOPAMINE D3 RECEPTORS IN SPONTANEOUSLY HYPERTENSIVE AND DEOXYCORTICOSTERONE ACETATE-SALT HYPERTENSIVE RATS: EFFECTS OF INTRARENALLY APPLIED SELECTIVE ANTAGONISTS.
Autorzy:
BADZYNSKA, B.
BARANOWSKA, I.
SADOWSKI, J.
Pokaż więcej
Temat:
DOPAMINE receptors
ENDOTHELINS
HYPERTENSION
BLOOD flow
RENAL artery
THIRST
Źródło:
Journal of Physiology & Pharmacology; Feb2024, Vol. 75 Issue 1, p11-22, 12p
Czasopismo naukowe
Tytuł:
Soluble Pearl Extract provides effective skin lightening by antagonizing endothelin.
Autorzy:
Wang, Jing (AUTHOR)
Chen, Zhixiong (AUTHOR)
Lu, Yaojia (AUTHOR)
Zhang, Lihua (AUTHOR)
Mo, Jiahuan (AUTHOR)
Cao, Fumin (AUTHOR)
Xie, Min (AUTHOR)
Shen, Xinzhong (AUTHOR)
Yang, Anquan (AUTHOR)
Pokaż więcej
Źródło:
Journal of Cosmetic Dermatology. Aug2021, Vol. 20 Issue 8, p2531-2537. 7p.
Czasopismo naukowe
Tytuł:
Targeting Endothelin in Alzheimer's Disease: A Promising Therapeutic Approach.
Autorzy:
Sharma S; Chitkara College of Pharmacy, Chitkara University, Punjab, India.
Behl T; Chitkara College of Pharmacy, Chitkara University, Punjab, India.
Kumar A; Delhi Pharmaceutical Sciences and Research University, Delhi, India.
Sehgal A; Chitkara College of Pharmacy, Chitkara University, Punjab, India.
Singh S; Chitkara College of Pharmacy, Chitkara University, Punjab, India.
Sharma N; Chitkara College of Pharmacy, Chitkara University, Punjab, India.
Bhatia S; Natural & Medical Sciences Research Centre, University of Nizwa, Nizwa, Oman.; Amity Institute of Pharmacy, Amity University, Haryana, India.
Al-Harrasi A; Natural & Medical Sciences Research Centre, University of Nizwa, Nizwa, Oman.
Bungau S; Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.
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Źródło:
BioMed research international [Biomed Res Int] 2021 Sep 06; Vol. 2021, pp. 7396580. Date of Electronic Publication: 2021 Sep 06 (Print Publication: 2021).
Typ publikacji:
Journal Article; Review
MeSH Terms:
Alzheimer Disease/*therapy
Endothelins/*drug effects
Endothelins/*metabolism
Alzheimer Disease/metabolism ; Amyloid beta-Peptides/metabolism ; Aspartic Acid Endopeptidases/metabolism ; Brain/metabolism ; Endothelial Cells/metabolism ; Endothelin-Converting Enzymes/metabolism ; Humans ; Neprilysin/genetics
Czasopismo naukowe
Tytuł:
Hyaluronan Production by Renomedullary Interstitial Cells: Influence of Endothelin, Angiotensin II and Vasopressin.
Autorzy:
Stridh S; Department of Medical Cell Biology, Uppsala University, Biomedical Center, SE-75123 Uppsala, Sweden. .; Department of Health Sciences, Red Cross University College, SE-14152 Stockholm, Sweden. .
Palm F; Department of Medical Cell Biology, Uppsala University, Biomedical Center, SE-75123 Uppsala, Sweden. .
Takahashi T; Faculty of Pharmaceutical Sciences, Hoshi University, Tokyo 142-8501, Japan. .
Ikegami-Kawai M; Faculty of Pharmaceutical Sciences, Hoshi University, Tokyo 142-8501, Japan.
Friederich-Persson M; Department of Medical Cell Biology, Uppsala University, Biomedical Center, SE-75123 Uppsala, Sweden.
Hansell P; Department of Medical Cell Biology, Uppsala University, Biomedical Center, SE-75123 Uppsala, Sweden. .
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2017 Dec 13; Vol. 18 (12). Date of Electronic Publication: 2017 Dec 13.
Typ publikacji:
Journal Article
MeSH Terms:
Angiotensin II/*pharmacology
Endothelins/*pharmacology
Hyaluronic Acid/*metabolism
Kidney Medulla/*drug effects
Vasopressins/*pharmacology
Animals ; Cells, Cultured ; Endothelins/metabolism ; Hyaluronan Receptors/metabolism ; Hyaluronan Synthases/genetics ; Hyaluronan Synthases/metabolism ; Hyaluronic Acid/analysis ; Hyaluronoglucosaminidase/antagonists & inhibitors ; Hyaluronoglucosaminidase/genetics ; Hyaluronoglucosaminidase/metabolism ; Hymecromone/pharmacology ; Kidney Medulla/cytology ; Kidney Medulla/metabolism ; Male ; RNA, Messenger/metabolism ; Rats ; Rats, Sprague-Dawley ; Receptor, Angiotensin, Type 1/metabolism ; Transcriptome/drug effects
Czasopismo naukowe
Tytuł:
血浆内皮素配合描记动态脑电图在儿童晕厥诊断中应用的临床意义.
Autorzy:
梁妍琰
苏学文
张国栋
伊儒晗
朱华
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Alternatywny tytuł:
Clinical Significance of Plasma Endothelin Combined with Tracing Dynamic Electroencephalogram in the Diagnosis of Syncope in Children.
Źródło:
Progress in Modern Biomedicine. 2021, Issue 12, p2340-2343. 4p.
Czasopismo naukowe
Tytuł:
Effect of positive end-expiratory pressure ventilation on plasma nitric oxide, endothelin-1 and vascular celladhesion molecule-1 levels in patients undergoing uvulopalatopharyngoplasty.
Autorzy:
Du, Yi-Ri (AUTHOR)
Shi, Hai-Xia (AUTHOR)
Yu, Jian-She (AUTHOR)
Wu-Lan, Na-Ri (AUTHOR)
Qian, Xu (AUTHOR)
Zhong, Hai-Yan (AUTHOR)
Pokaż więcej
Źródło:
Technology & Health Care. 2021, Vol. 29 Issue 2, p223-229. 7p.
Czasopismo naukowe
Tytuł:
Endothelins and carcinogenesis.
Autorzy:
Olender J; Katedra i Zakład Biologii Molekularnej, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej w Sosnowcu, Śląski Uniwersytet Medyczny w Katowicach.
Nowakowska-Zajdel E; Katedra i Oddział Kliniczny Chorób Wewnętrznych, Wydział Zdrowia Publicznego w Bytomiu, Śląski Uniwersytet Medyczny w Katowicach Specjalistyczny Szpital nr 1 w Bytomiu.
Walkiewicz K; Katedra i Oddział Kliniczny Chorób Wewnętrznych, Wydział Zdrowia Publicznego w Bytomiu, Śląski Uniwersytet Medyczny w Katowicach Specjalistyczny Szpital nr 1 w Bytomiu.
Muc-Wierzgoń M; Katedra i Oddział Kliniczny Chorób Wewnętrznych, Wydział Zdrowia Publicznego w Bytomiu, Śląski Uniwersytet Medyczny w Katowicach Specjalistyczny Szpital nr 1 w Bytomiu.
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Źródło:
Postepy higieny i medycyny doswiadczalnej (Online) [Postepy Hig Med Dosw (Online)] 2016 Aug 17; Vol. 70 (0), pp. 872-80. Date of Electronic Publication: 2016 Aug 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Endothelins*
Carcinogenesis/*metabolism
Endothelin Receptor Antagonists/*therapeutic use
Neoplasms/*metabolism
Animals ; Humans ; Neoplasms/diagnosis ; Neoplasms/drug therapy ; Neoplasms/pathology
Czasopismo naukowe
Tytuł:
Fluoxetine exerts anti‐inflammatory effects on human epidermal keratinocytes and suppresses their endothelin release.
Autorzy:
Tóth, Kinga Fanni
Ádám, Dorottya
Arany, József
Ramirez, Yesid A.
Bíró, Tamás
Drake, Jennifer I.
O'Mahony, Alison
Szöllősi, Attila Gábor
Póliska, Szilárd
Kilić, Ana
Soeberdt, Michael
Abels, Christoph
Oláh, Attila
Pokaż więcej
Temat:
FLUOXETINE
LIPOXINS
ENDOTHELINS
PHOSPHATIDYLINOSITOL 3-kinases
KERATINOCYTES
TOPICAL drug administration
Źródło:
Experimental Dermatology; Jan2024, Vol. 33 Issue 1, p1-15, 15p
Czasopismo naukowe
Tytuł:
In vitro pharmacological characterization of standard and new lysophosphatidic acid receptor antagonists using dynamic mass redistribution assay.
Autorzy:
Ruzza, C.
Argentieri, M.
Ferrari, F.
Armani, E.
Trevisani, M.
Marchini, G.
Calo, G.
Pokaż więcej
Temat:
LYSOPHOSPHOLIPIDS
G protein coupled receptors
CALCIUM antagonists
TYPE 2 diabetes
ENDOTHELINS
NEURALGIA
Źródło:
Frontiers in Pharmacology; 2023, p1-15, 15p
Przedsiębiorstwo/ jednostka:
MERCK KGaA
AMGEN Inc.
Czasopismo naukowe
Tytuł:
Endothelin Modulates Rhythm Disturbances and Autonomic Responses to Acute Emotional Stress in Rats.
Autorzy:
Mouchtouri, Eleni-Taxiarchia
Konstantinou, Thomas
Lekkas, Panagiotis
Lianopoulou, Alexandra
Kotsaridou, Zoi
Mourouzis, Iordanis
Pantos, Constantinos
Kolettis, Theofilos M.
Pokaż więcej
Temat:
PSYCHOLOGICAL stress
VAGAL tone
ARRHYTHMIA
ACUTE stress disorder
ENDOTHELINS
HEART beat
Źródło:
Biology (2079-7737); Nov2023, Vol. 12 Issue 11, p1401, 16p
Czasopismo naukowe
Tytuł:
Serum concentration of endocan, fetuin-A, and endothelin in plaque psoriasis - coincidence or fate? A preliminary study.
Autorzy:
Grochowiec, Marcelina
Narbutt, Joanna
Lesiak, Aleksandra
Pokaż więcej
Alternatywny tytuł:
Stężenia endokanu, fetuiny A i endoteliny w surowicy pacjentów z łuszczycą plackowatą - przypadek czy prawidłowość? Badanie wstępne.
Źródło:
Dermatology Review / Przeglad Dermatologiczny. 2021, Vol. 108 Issue 1, p16-26. 11p.
Czasopismo naukowe
Tytuł:
HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury.
Autorzy:
Aufhauser DD Jr; Department of Surgery, University of Wisconsin, Madison, WI, USA.
Hernandez P; Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA.
Concors SJ; Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA.
O'Brien C; Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA.
Wang Z; Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA.
Murken DR; Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA.
Samanta A; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Beier UH; Division of Nephrology, Department of Pediatrics, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA, USA.
Krumeich L; Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA.
Bhatti TR; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Wang Y; Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA.
Ge G; Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA.
Wang L; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Cheraghlou S; School of Medicine, Yale University, New Haven, CT, USA.
Wagner FF; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Holson EB; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
Kalin JH; Division of Genetics, Departments of Medicine and Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.
Cole PA; Division of Genetics, Departments of Medicine and Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.
Hancock WW; Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Levine MH; Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA. .; Department of Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2021 Apr 27; Vol. 11 (1), pp. 9018. Date of Electronic Publication: 2021 Apr 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Co-Repressor Proteins/*metabolism
Histone Deacetylase 2/*metabolism
Kidney Tubules, Proximal/*metabolism
Reperfusion Injury/*prevention & control
Animals ; Co-Repressor Proteins/antagonists & inhibitors ; Endothelins/metabolism ; Enzyme Inhibitors/pharmacology ; Female ; Gene Deletion ; Histone Deacetylase 1/antagonists & inhibitors ; Histone Deacetylase 1/genetics ; Histone Deacetylase 1/metabolism ; Histone Deacetylase 2/antagonists & inhibitors ; Histone Deacetylase 2/genetics ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/metabolism ; Kidney Tubules, Proximal/drug effects ; Male ; Mice ; Mice, Knockout
Czasopismo naukowe
Tytuł:
Pressure for change: can we continue to ignore the lack of evidence for blood pressure augmentation to treat delayed neurological deficit following subarachnoid haemorrhage?
Autorzy:
O'Leary, Ronan
Coles, Jonathan P.
Prisco, Lara
Pokaż więcej
Temat:
PATIENT safety
SUBARACHNOID hemorrhage
HYPERTENSION
CEREBRAL ischemia
CEREBRAL circulation
CEREBRAL infarction
CORONARY vasospasm
ENDOTHELINS
CELL receptors
DISEASE complications
CHEMICAL inhibitors
Źródło:
Annals of Intensive Care; 4/1/2024, Vol. 14 Issue 1, p1-3, 3p
Czasopismo naukowe
Tytuł:
Impact of Superoxide Dismutase Mimetic AEOL 10150 on the Endothelin System of Fischer 344 Rats.
Autorzy:
Ganesh D; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Environmental Health Science and Research Bureau, Environmental and Radiation Health Sciences Directorate, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada.
Kumarathasan P; Environmental Health Science and Research Bureau, Environmental and Radiation Health Sciences Directorate, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada.
Thomson EM; Environmental Health Science and Research Bureau, Environmental and Radiation Health Sciences Directorate, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada.
St-Germain C; Environmental Health Science and Research Bureau, Environmental and Radiation Health Sciences Directorate, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada.
Blais E; Environmental Health Science and Research Bureau, Environmental and Radiation Health Sciences Directorate, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada.
Crapo J; National Jewish Health, Denver, Colorado, United States of America.
Vincent R; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.; Environmental Health Science and Research Bureau, Environmental and Radiation Health Sciences Directorate, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2016 Mar 18; Vol. 11 (3), pp. e0151810. Date of Electronic Publication: 2016 Mar 18 (Print Publication: 2016).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antioxidants/*pharmacology
Endothelins/*blood
Metalloporphyrins/*pharmacology
Superoxide Dismutase/*pharmacology
Animals ; Biomarkers/blood ; Chromatography, High Pressure Liquid ; Endothelins/metabolism ; Homeostasis/drug effects ; Male ; Oxidative Stress ; Rats, Inbred F344 ; Reactive Nitrogen Species/metabolism ; Reactive Oxygen Species/metabolism ; Superoxide Dismutase/chemistry ; Vasoconstriction/drug effects
Czasopismo naukowe
Tytuł:
Levels of nitric oxide metabolites, adiponectin and endothelin are associated with SNPs of the adiponectin and endothelin genes.
Autorzy:
Gumanova, Nadezhda G. (AUTHOR)
Klimushina, Marina V. (AUTHOR)
Smetnev, Stepan A. (AUTHOR)
Kiseleva, Anna V. (AUTHOR)
Skirko, Olga P. (AUTHOR)
Meshkov, Alexey N. (AUTHOR)
Shanoyan, Artem S. (AUTHOR)
Kots, Alexander Y. (AUTHOR)
Metelskaya, Victoria A. (AUTHOR)
Pokaż więcej
Źródło:
Biomedical Reports. Oct2019, Vol. 11 Issue 4, p154-164. 11p.
Czasopismo naukowe
Tytuł:
The EDN2 rs110287192 gene polymorphism is associated with paratuberculosis susceptibility in multibreed cattle population.
Autorzy:
Çınar MU; Department of Animal Science, Faculty of Agriculture, Erciyes University, Kayseri, Turkey.; Department of Veterinary Microbiology & Pathology, Washington State University, Pullman, WA, United States of America.
Akyüz B; Department of Genetics, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkey.
Arslan K; Department of Genetics, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkey.
White SN; Department of Veterinary Microbiology & Pathology, Washington State University, Pullman, WA, United States of America.; Animal Disease Research Unit, Agricultural Research Service, U.S. Department of Agriculture, Pullman, WA, United States of America.; Center for Reproductive Biology, Washington State University, Pullman, WA, United States of America.
Neibergs HL; Center for Reproductive Biology, Washington State University, Pullman, WA, United States of America.; Department of Animal Science, Washington State University, Pullman, WA, United States of America.
Gümüşsoy KS; Department of Microbiology, Erciyes University, Faculty of Veterinary Medicine, Kayseri, Turkey.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2020 Sep 03; Vol. 15 (9), pp. e0238631. Date of Electronic Publication: 2020 Sep 03 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breeding*
Genetic Predisposition to Disease*
Cattle/*genetics
Cattle/*microbiology
Endothelins/*genetics
Paratuberculosis/*genetics
Polymorphism, Single Nucleotide/*genetics
Alleles ; Animals ; Logistic Models ; Paratuberculosis/microbiology
Czasopismo naukowe
Tytuł:
Sovateltide (IRL-1620) affects neuronal progenitors and prevents cerebral tissue damage after ischemic stroke.
Autorzy:
Ranjan AK; Chicago College of Pharmacy, Midwestern University, Downers Grove, IL 60515, USA.
Briyal S; Chicago College of Pharmacy, Midwestern University, Downers Grove, IL 60515, USA.
Khandekar D; Chicago College of Pharmacy, Midwestern University, Downers Grove, IL 60515, USA.
Gulati A; Chicago College of Pharmacy, Midwestern University, Downers Grove, IL 60515, USA.; Pharmazz Inc. Research and Development, Willowbrook, IL 60527, USA.
Pokaż więcej
Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2020 Sep; Vol. 98 (9), pp. 659-666. Date of Electronic Publication: 2020 Jun 23.
Typ publikacji:
Journal Article
MeSH Terms:
Brain/*drug effects
Endothelins/*administration & dosage
Infarction, Middle Cerebral Artery/*drug therapy
Ischemic Stroke/*drug therapy
Peptide Fragments/*administration & dosage
Stem Cells/*drug effects
Animals ; Brain/pathology ; Cell Differentiation/drug effects ; DNA Damage/drug effects ; Disease Models, Animal ; Humans ; Infarction, Middle Cerebral Artery/complications ; Infarction, Middle Cerebral Artery/pathology ; Injections, Intravenous ; Ischemic Stroke/etiology ; Ischemic Stroke/pathology ; Male ; Nerve Regeneration/drug effects ; Neurons/drug effects ; Neurons/pathology ; Rats ; Receptor, Endothelin B/agonists ; Receptor, Endothelin B/metabolism ; Stem Cells/pathology
Czasopismo naukowe
Tytuł:
Expression of Endothelin-1, Endothelin Receptor-A, and Endothelin Receptor-B in facial melasma compared to adjacent skin.
Autorzy:
da Silva, Carolina Nunhez
Miot, Hélio Amante
Grassi, Tony Fernando
Dias-Melício, Luciane Alarcão
Santos, Leandro
Espósito, Ana Cláudia Cavalcante
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Temat:
MELANOSIS
ENDOTHELINS
PREPROENDOTHELIN
LASER microscopy
CONFOCAL microscopy
Źródło:
Clinical, Cosmetic & Investigational Dermatology; Oct2023, Vol. 16, p2847-2853, 7p
Czasopismo naukowe
Tytuł:
Tumor Necrosis Factor (TNF) α, Endothelin (ET) 1 and α1-Acid Glycoprotein (AGP) as Potential Urine and Serum Markers of Metabolic Complications in Psoriasis?
Autorzy:
Nowowiejska, Julia
Baran, Anna
Hermanowicz, Justyna M.
Sieklucka, Beata
Pawlak, Dariusz
Flisiak, Iwona
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Temat:
TUMOR necrosis factors
BIOMARKERS
PREPROENDOTHELIN
PSORIASIS
ENDOTHELINS
URINE collection & preservation
Źródło:
Dermatology & Therapy; Oct2023, Vol. 13 Issue 10, p2217-2227, 11p
Czasopismo naukowe
Tytuł:
Immunohisto-chemical Localization of Endothelin- 1 and Endothelin A Receptor in Human Primary Tooth Enamel Organ.
Autorzy:
Irani, Soussan
Alimohammadi, Shohreh
Najafian, Tahmine
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Temat:
EXPERIMENTAL design
STATISTICS
STAINS & staining (Microscopy)
ANALYSIS of variance
ENDOTHELINS
IMMUNOHISTOCHEMISTRY
INCISORS
MOLARS
MANDIBLE
CELL receptors
FETAL development
GENE expression profiling
RESEARCH funding
DESCRIPTIVE statistics
CELL proliferation
DENTAL enamel
DATA analysis software
DATA analysis
FETUS
Źródło:
Journal of Dentistry (2345-6485); Sep2023, Vol. 24 Issue 3, p328-334, 7p
Czasopismo naukowe
Tytuł:
Cerebrospinal fluid from patients with subarachnoid haemorrhage and vasospasm enhances endothelin contraction in rat cerebral arteries.
Autorzy:
Assenzio B; Department of Anesthesia and Intensive Care, Azienda Ospedaliera Città della salute e della scienza di Torino, University of Turin, Turin, Italy.
Martin EL; Department of Anesthesia and Intensive Care, Azienda Ospedaliera Città della salute e della scienza di Torino, University of Turin, Turin, Italy.
Stankevicius E; Institute of Physiology and Pharmacology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Civiletti F; Department of Anesthesia and Intensive Care, Azienda Ospedaliera Città della salute e della scienza di Torino, University of Turin, Turin, Italy.
Fontanella M; Division of Neurosurgery, Department of Neuroscience, Azienda Ospedaliera Città della salute e della scienza di Torino, University of Turin, Turin, Italy.
Boccaletti R; Division of Neurosurgery, Department of Neuroscience, Azienda Ospedaliera Città della salute e della scienza di Torino, University of Turin, Turin, Italy.
Berardino M; Department of Anesthesia and Intensive Care, Azienda Ospedaliera Città della salute e della scienza di Torino, University of Turin, Turin, Italy.
Mazzeo A; Department of Anesthesia and Intensive Care, Azienda Ospedaliera Città della salute e della scienza di Torino, University of Turin, Turin, Italy.
Ducati A; Division of Neurosurgery, Department of Neuroscience, Azienda Ospedaliera Città della salute e della scienza di Torino, University of Turin, Turin, Italy.
Simonsen U; Department of Biomedicine, Pulmonary and Cardiovascular Pharmacology, University of Aarhus, Aarhus, Denmark.
Mascia L; Department of Anesthesia and Intensive Care, Azienda Ospedaliera Città della salute e della scienza di Torino, University of Turin, Turin, Italy.
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Źródło:
PloS one [PLoS One] 2015 Jan 28; Vol. 10 (1), pp. e0116456. Date of Electronic Publication: 2015 Jan 28 (Print Publication: 2015).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cerebral Arteries/*drug effects
Cerebral Arteries/*metabolism
Endothelins/*metabolism
Subarachnoid Hemorrhage/*cerebrospinal fluid
Vasoconstriction/*drug effects
Aged ; Animals ; Cerebrospinal Fluid ; Endothelin Receptor Antagonists/pharmacology ; Endothelin-1/pharmacology ; Endothelins/pharmacology ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/metabolism ; Female ; Humans ; Male ; Middle Aged ; Rats ; Receptors, Endothelin/metabolism
Czasopismo naukowe
Tytuł:
Increases in [IP3]i aggravates diastolic [Ca2+] and contractile dysfunction in Chagas' human cardiomyocytes.
Autorzy:
Mijares A; Centro de Biofísica y Bioquímica, Instituto Venezolano de Investigaciones Científicas, Caracas, Venezuela.
Espinosa R; Departamento de Cardiología, Hospital Miguel Pérez Carreño, Instituto venezolano de los Seguros Sociales, Caracas, Venezuela.
Adams J; Division of Neonatology, Mount Sinai, Medical Center, Miami, FL, United States of America.
Lopez JR; Department of Research, Mount Sinai, Medical Center, Miami, FL, United States of America.
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Apr 10; Vol. 14 (4), pp. e0008162. Date of Electronic Publication: 2020 Apr 10 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Calcium/*metabolism
Chagas Cardiomyopathy/*metabolism
Inositol 1,4,5-Trisphosphate/*metabolism
Inositol 1,4,5-Trisphosphate Receptors/*metabolism
Myocytes, Cardiac/*metabolism
Adult ; Bradykinin/metabolism ; Cell Membrane Permeability ; Endothelins/metabolism ; Female ; Humans ; Macrocyclic Compounds/metabolism ; Male ; Middle Aged ; Oxazoles/metabolism ; Quality of Life ; Sarcoplasmic Reticulum/metabolism ; Sodium/metabolism
Czasopismo naukowe
Tytuł:
Comparison of the protective effects of selective endothelin-a receptor antagonist, ambrisentan, and dual endothelin-A/B receptor antagonist, bosentan, in experimental renal ischemia reperfusion injury.
Autorzy:
Kazimoglu H
Uysal E
Dokur M
Gurer AO
Batcioglu K
Uyumlu BA
Petekkaya E
Karadag M
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Źródło:
Bratislavske lekarske listy [Bratisl Lek Listy] 2020; Vol. 121 (8), pp. 547-553.
Typ publikacji:
Journal Article
MeSH Terms:
Bosentan*/therapeutic use
Endothelin Receptor Antagonists*/therapeutic use
Phenylpropionates*/therapeutic use
Pyridazines*/therapeutic use
Reperfusion Injury*/drug therapy
Animals ; Endothelins ; Female ; Rats ; Receptor, Endothelin A ; Sulfonamides
Czasopismo naukowe
Tytuł:
A focus on riociguat in the treatment of pulmonary arterial hypertension.
Autorzy:
Toxvig AK; Department of Biomedicine, Pharmacology, Aarhus University, Aarhus C, Denmark.
Wehland M; Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Grimm D; Department of Biomedicine, Pharmacology, Aarhus University, Aarhus C, Denmark.; Department of Microgravity and Translational Regenerative Medicine, Faculty of Medicine and Mechanical Engineering, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Infanger M; Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Krüger M; Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University Magdeburg, Magdeburg, Germany.
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Źródło:
Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2019 Sep; Vol. 125 (3), pp. 202-214. Date of Electronic Publication: 2019 Jul 04.
Typ publikacji:
Comparative Study; Journal Article; Review
MeSH Terms:
Enzyme Activators/*pharmacology
Pulmonary Arterial Hypertension/*drug therapy
Pyrazoles/*pharmacology
Pyrimidines/*pharmacology
Signal Transduction/*drug effects
Animals ; Disease Models, Animal ; Drug Substitution ; Endothelins/metabolism ; Enzyme Activators/therapeutic use ; Epoprostenol/metabolism ; Guanylate Cyclase/metabolism ; Humans ; Nitric Oxide/metabolism ; Phosphodiesterase 5 Inhibitors/pharmacology ; Phosphodiesterase 5 Inhibitors/therapeutic use ; Pulmonary Arterial Hypertension/physiopathology ; Pulmonary Artery/drug effects ; Pulmonary Artery/physiopathology ; Pyrazoles/therapeutic use ; Pyrimidines/therapeutic use ; Randomized Controlled Trials as Topic ; Treatment Outcome ; Vasodilation/drug effects
Czasopismo naukowe
Tytuł:
The Key Role of Epithelial to Mesenchymal Transition (EMT) in Hypertensive Kidney Disease.
Autorzy:
Seccia TM; Hypertension Unit, Department of Medicine-DIMED, University Hospital, 35128 Padova, Italy.
Caroccia B; Hypertension Unit, Department of Medicine-DIMED, University Hospital, 35128 Padova, Italy.
Piazza M; Hypertension Unit, Department of Medicine-DIMED, University Hospital, 35128 Padova, Italy.
Rossi GP; Hypertension Unit, Department of Medicine-DIMED, University Hospital, 35128 Padova, Italy. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Jul 21; Vol. 20 (14). Date of Electronic Publication: 2019 Jul 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Epithelial-Mesenchymal Transition*
Hypertension, Renal/*etiology
Hypertension, Renal/*pathology
Nephritis/*etiology
Nephritis/*pathology
Angiotensin II/metabolism ; Animals ; Biomarkers ; Disease Susceptibility ; Endothelins/metabolism ; Fibrosis ; Humans ; Hypertension/complications ; Hypertension, Renal/metabolism ; Nephritis/metabolism
SCR Disease Name:
Hypertensive Nephropathy
Czasopismo naukowe
Tytuł:
Epigenetics: A Potential Mechanism Involved in the Pathogenesis of Various Adverse Consequences of Obstructive Sleep Apnea.
Autorzy:
Chen YC; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan. .; Department of Medicine, College of Medicine, Chang Gung University, Taouyan 33302, Taiwan. .
Hsu PY; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan. .; Department of medical research, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan. .
Hsiao CC; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan. .; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taouyan 33302, Taiwan. .
Lin MC; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Jun 15; Vol. 20 (12). Date of Electronic Publication: 2019 Jun 15.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Epigenesis, Genetic*
Genetic Predisposition to Disease*
Sleep Apnea, Obstructive/*etiology
Animals ; DNA Methylation ; Endothelins/metabolism ; Gene Expression Regulation ; Genetic Association Studies ; Histones/metabolism ; Humans ; Hypoxia/genetics ; Hypoxia/metabolism ; Hypoxia-Inducible Factor 1/metabolism ; MicroRNAs/genetics ; NF-kappa B/metabolism ; RNA, Untranslated/genetics ; Reactive Oxygen Species/metabolism ; Signal Transduction ; Sleep Apnea, Obstructive/metabolism ; Toll-Like Receptors/metabolism
Czasopismo naukowe
Tytuł:
Increased endothelin‐1‐mediated vasoconstriction after organ culture in rat and pig ocular arteries can be suppressed with MEK/ERK1/2 inhibitors.
Autorzy:
Blixt, Frank W.
Haanes, Kristian Agmund
Ohlsson, Lena
Tolstrup Christiansen, Anders
Warfvinge, Karin
Edvinsson, Lars
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Źródło:
Acta Ophthalmologica (1755375X). Aug2018, Vol. 96 Issue 5, pe619-e625. 7p.
Czasopismo naukowe
Tytuł:
Endothelin: 20 years from discovery to therapy.
Autorzy:
Barton M; Klinik und Poliklinik für Innere Medizin, Departement für Innere Medizin, Universitätsspital Zürich, Zürich, Switzerland. />Yanagisawa M
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Źródło:
Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2008 Aug; Vol. 86 (8), pp. 485-98.
Typ publikacji:
Historical Article; Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Endothelins/*history
Endothelins/*physiology
Animals ; Endothelins/immunology ; Endothelins/therapeutic use ; History, 20th Century ; Humans ; Receptors, Endothelin/drug effects ; Receptors, Endothelin/physiology
Czasopismo naukowe
Tytuł:
Human chorionic villous mesenchymal stem/stromal cells protect endothelial cells from injury induced by high level of glucose.
Autorzy:
Basmaeil YS; Stem Cells and Regenerative Medicine Department, King Abdullah International Medical Research Centre, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, P.O. Box 22490, Mail Code 1515, Riyadh, 11426, Saudi Arabia.
Al Subayyil AM; Stem Cells and Regenerative Medicine Department, King Abdullah International Medical Research Centre, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, P.O. Box 22490, Mail Code 1515, Riyadh, 11426, Saudi Arabia.
Khatlani T; Stem Cells and Regenerative Medicine Department, King Abdullah International Medical Research Centre, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, P.O. Box 22490, Mail Code 1515, Riyadh, 11426, Saudi Arabia.
Bahattab E; National Center for Stem Cell Technology, Life Sciences and Environment Research Institute, King Abdulaziz City for Science and Technology, P.O. Box 6086, Riyadh, 11442, Saudi Arabia.
Al-Alwan M; Stem Cell and Tissue Re-Engineering Program, King Faisal Specialist Hospital and Research Centre, Collage of Medicine, Al-Faisal University, MBC-03, P.O. Box 3354, Riyadh, 11211, Saudi Arabia.
Abomaray FM; Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 14186, Stockholm, Sweden.; Center for Hematology and Regenerative Medicine, Karolinska Institutet, 14186, Stockholm, Sweden.
Kalionis B; Department of Maternal-Fetal Medicine Pregnancy Research Centre and University of Melbourne Department of Obstetrics and Gynaecology, Royal Women's Hospital, Parkville, VIC, 3052, Australia.
Alshabibi MA; Stem Cells and Regenerative Medicine Department, King Abdullah International Medical Research Centre, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, P.O. Box 22490, Mail Code 1515, Riyadh, 11426, Saudi Arabia.
AlAskar AS; Stem Cells and Regenerative Medicine Department, King Abdullah International Medical Research Centre, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, P.O. Box 22490, Mail Code 1515, Riyadh, 11426, Saudi Arabia.; College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, P.O. Box 3660, Mail Code 3124, Riyadh, 11481, Saudi Arabia.; Adult Hematology and Stem Cell Transplantation, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, P.O. Box 22490, Mail Code 1515, Riyadh, 11426, Saudi Arabia.
Abumaree MH; Stem Cells and Regenerative Medicine Department, King Abdullah International Medical Research Centre, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, P.O. Box 22490, Mail Code 1515, Riyadh, 11426, Saudi Arabia. .; College of Science and Health Professions, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, P.O. Box 3660, Mail Code 3124, Riyadh, 11481, Saudi Arabia. .
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Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2018 Sep 21; Vol. 9 (1), pp. 238. Date of Electronic Publication: 2018 Sep 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Culture Media, Conditioned/*pharmacology
Gene Expression Regulation/*drug effects
Glucose/*pharmacology
Human Umbilical Vein Endothelial Cells/*drug effects
Mesenchymal Stem Cells/*metabolism
Apoptosis/drug effects ; Cell Membrane Permeability/drug effects ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Chemokines/genetics ; Chemokines/metabolism ; Chorionic Villi/metabolism ; Coculture Techniques ; Collagen/chemistry ; Collagen/genetics ; Collagen/metabolism ; Drug Combinations ; Endothelins/genetics ; Endothelins/metabolism ; Female ; Glucose/antagonists & inhibitors ; Human Umbilical Vein Endothelial Cells/cytology ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Interleukins/genetics ; Interleukins/metabolism ; Laminin/chemistry ; Membrane Glycoproteins/genetics ; Membrane Glycoproteins/metabolism ; Mesenchymal Stem Cells/cytology ; Pregnancy ; Proteoglycans/chemistry ; Receptors, Cell Surface/genetics ; Receptors, Cell Surface/metabolism ; Signal Transduction ; THP-1 Cells ; Umbilical Cord/cytology ; Umbilical Cord/metabolism
Czasopismo naukowe

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