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Tytuł:
TrkB-mediated neuroprotection in female hippocampal neurons is autonomous, estrogen receptor alpha-dependent, and eliminated by testosterone: a proposed model for sex differences in neonatal hippocampal neuronal injury.
Autorzy:
Chanana V; Waisman Center, University of Wisconsin, Madison, WI, USA.; Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Wisconsin, 1500 Highland Ave - T505, Madison, WI, 53705-9345, USA.
Zafer D; Waisman Center, University of Wisconsin, Madison, WI, USA.; Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Wisconsin, 1500 Highland Ave - T505, Madison, WI, 53705-9345, USA.
Kintner DB; Waisman Center, University of Wisconsin, Madison, WI, USA.; Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Wisconsin, 1500 Highland Ave - T505, Madison, WI, 53705-9345, USA.
Chandrashekhar JH; Waisman Center, University of Wisconsin, Madison, WI, USA.; University of Illinois at Urbana-Champaign, Champaign, IL, USA.
Eickhoff J; Department of Statistics and Bioinformatics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Ferrazzano PA; Waisman Center, University of Wisconsin, Madison, WI, USA.; Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Wisconsin, 1500 Highland Ave - T505, Madison, WI, 53705-9345, USA.
Levine JE; Department of Neuroscience, University of Wisconsin, Madison, WI, USA.; Wisconsin National Primate Research Center, Madison, WI, USA.
Cengiz P; Waisman Center, University of Wisconsin, Madison, WI, USA. .; Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Wisconsin, 1500 Highland Ave - T505, Madison, WI, 53705-9345, USA. .
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Źródło:
Biology of sex differences [Biol Sex Differ] 2024 Apr 02; Vol. 15 (1), pp. 30. Date of Electronic Publication: 2024 Apr 02.
Typ publikacji:
Journal Article
MeSH Terms:
Estrogen Receptor alpha*/metabolism
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/metabolism
Child ; Female ; Animals ; Male ; Mice ; Humans ; Neuroprotection ; Sex Characteristics ; Testosterone/pharmacology ; Testosterone/metabolism ; Neurons/metabolism ; Hippocampus/metabolism ; Ischemia ; Hypoxia/metabolism ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł:
High estrogen during ovarian stimulation induced loss of maternal imprinted methylation that is essential for placental development via overexpression of TET2 in mouse oocytes.
Autorzy:
Lu X; Reproductive Medicine Center, Department of Gynecology and Obstetrics, Tangdu Hospital, Air Force Medical University, No.1, Xinsi Road, Baqiao District, Xi'an, 710000, Shaanxi Province, China.
Mao J; Reproductive Medicine Center, Department of Gynecology and Obstetrics, Tangdu Hospital, Air Force Medical University, No.1, Xinsi Road, Baqiao District, Xi'an, 710000, Shaanxi Province, China.
Qian C; Reproductive Medicine Center, Department of Gynecology and Obstetrics, Tangdu Hospital, Air Force Medical University, No.1, Xinsi Road, Baqiao District, Xi'an, 710000, Shaanxi Province, China.
Lei H; Reproductive Medicine Center, Department of Gynecology and Obstetrics, Tangdu Hospital, Air Force Medical University, No.1, Xinsi Road, Baqiao District, Xi'an, 710000, Shaanxi Province, China.
Mu F; Department of Pharmacy, Xijing Hospital, Air Force Medical University, Xi'an, Shaanxi, China.
Sun H; Reproductive Medicine Center, Department of Gynecology and Obstetrics, Tangdu Hospital, Air Force Medical University, No.1, Xinsi Road, Baqiao District, Xi'an, 710000, Shaanxi Province, China.
Yan S; Reproductive Medicine Center, Department of Gynecology and Obstetrics, Tangdu Hospital, Air Force Medical University, No.1, Xinsi Road, Baqiao District, Xi'an, 710000, Shaanxi Province, China.
Fang Z; Reproductive Medicine Center, Department of Gynecology and Obstetrics, Tangdu Hospital, Air Force Medical University, No.1, Xinsi Road, Baqiao District, Xi'an, 710000, Shaanxi Province, China.
Lu J; Reproductive Medicine Center, Department of Gynecology and Obstetrics, Tangdu Hospital, Air Force Medical University, No.1, Xinsi Road, Baqiao District, Xi'an, 710000, Shaanxi Province, China.
Xu Q; Reproductive Medicine Center, Department of Gynecology and Obstetrics, Tangdu Hospital, Air Force Medical University, No.1, Xinsi Road, Baqiao District, Xi'an, 710000, Shaanxi Province, China.
Dong J; Reproductive Medicine Center, Department of Gynecology and Obstetrics, Tangdu Hospital, Air Force Medical University, No.1, Xinsi Road, Baqiao District, Xi'an, 710000, Shaanxi Province, China.
Su D; Reproductive Medicine Center, Department of Gynecology and Obstetrics, Tangdu Hospital, Air Force Medical University, No.1, Xinsi Road, Baqiao District, Xi'an, 710000, Shaanxi Province, China.
Wang J; Reproductive Medicine Center, Department of Gynecology and Obstetrics, Tangdu Hospital, Air Force Medical University, No.1, Xinsi Road, Baqiao District, Xi'an, 710000, Shaanxi Province, China.
Jin N; Reproductive Medicine Center, Department of Gynecology and Obstetrics, Tangdu Hospital, Air Force Medical University, No.1, Xinsi Road, Baqiao District, Xi'an, 710000, Shaanxi Province, China.
Chen S; Reproductive Medicine Center, Department of Gynecology and Obstetrics, Tangdu Hospital, Air Force Medical University, No.1, Xinsi Road, Baqiao District, Xi'an, 710000, Shaanxi Province, China. .
Wang X; Reproductive Medicine Center, Department of Gynecology and Obstetrics, Tangdu Hospital, Air Force Medical University, No.1, Xinsi Road, Baqiao District, Xi'an, 710000, Shaanxi Province, China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Feb 19; Vol. 22 (1), pp. 135. Date of Electronic Publication: 2024 Feb 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Estrogen Receptor alpha*/metabolism
Dioxygenases*/metabolism
Mice ; Female ; Pregnancy ; Animals ; Placentation ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Placenta/metabolism ; Proto-Oncogene Proteins/metabolism ; DNA Methylation ; Oocytes/metabolism ; Ovulation Induction ; DNA/metabolism ; Estrogens/metabolism
Czasopismo naukowe
Tytuł:
Estrogen Receptor α Isoforms Generated by Alternative Use of Cryptic Exons.
Autorzy:
Ishii H; Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School.
Hattori Y; Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School.
Ozawa H; Department of Anatomy and Neurobiology, Graduate School of Medicine, Nippon Medical School.
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Źródło:
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi [J Nippon Med Sch] 2023 Nov 07; Vol. 90 (5), pp. 364-371. Date of Electronic Publication: 2023 Aug 08.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Estrogen Receptor alpha*/genetics
Estrogen Receptor alpha*/metabolism
Alternative Splicing*/genetics
Humans ; Rats ; Mice ; Animals ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Exons/genetics ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł:
Exploring the association of ESR1 and ESR2 gene SNPs with polycystic ovary syndrome in human females: a comprehensive association study.
Autorzy:
Muccee F; School of Biochemistry and Biotechnology, University of Punjab, Lahore, 52254, Pakistan. .
Ashraf NM; School of Biochemistry and Biotechnology, University of Punjab, Lahore, 52254, Pakistan.
Razak S; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, 11451, Saudi Arabia. .
Afsar T; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, 11451, Saudi Arabia.
Hussain N; Department of Pharmaceutical Sciences, College of Pharmacy, Al Ain University, Al Ain Campus, 64141, Al Ain, United Arab Emirates.; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi Campus, P. O. Box 112612, Abu Dhabi, United Arab Emirates.
Husain FM; Department of Food Science and Nutrition, College of Food and Agriculture Sciences, King Saud University, Riyadh, 11451, Saudi Arabia.
Shafique H; Institute of Cellular Medicine, Newcastle University Medical School, Newcastle University Newcastle Upon Tyne, Newcastle upon Tyne, UK.
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Źródło:
Journal of ovarian research [J Ovarian Res] 2024 Jan 29; Vol. 17 (1), pp. 27. Date of Electronic Publication: 2024 Jan 29.
Typ publikacji:
Journal Article
MeSH Terms:
Estrogen Receptor alpha*/genetics
Estrogen Receptor beta*/genetics
Polycystic Ovary Syndrome*/genetics
Polymorphism, Single Nucleotide*
Female ; Humans ; Estradiol
Czasopismo naukowe
Tytuł:
Correlation between ESR1 and APOE gene polymorphisms and risk of osteonecrosis of the femoral head: a case-control study.
Autorzy:
Wang Y; College of Life Sciences, Northwest University, Xi'an, 710069, Shaanxi, China.; Provincial Key Laboratory of Biotechnology of Shaanxi, Northwest University, Xi'an, 710069, Shaanxi, China.; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Life Sciences, Northwest University, Xi'an, 710069, Shaanxi, China.; Department of Joint Surgery, Affiliated Hospital of Weifang Medical University, Weifang, 261031, Shandong, China.
Ma X; College of Life Sciences, Northwest University, Xi'an, 710069, Shaanxi, China.; Provincial Key Laboratory of Biotechnology of Shaanxi, Northwest University, Xi'an, 710069, Shaanxi, China.; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Life Sciences, Northwest University, Xi'an, 710069, Shaanxi, China.
Guo J; College of Life Sciences, Northwest University, Xi'an, 710069, Shaanxi, China.; Provincial Key Laboratory of Biotechnology of Shaanxi, Northwest University, Xi'an, 710069, Shaanxi, China.; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Life Sciences, Northwest University, Xi'an, 710069, Shaanxi, China.
Li Y; College of Life Sciences, Northwest University, Xi'an, 710069, Shaanxi, China.; Provincial Key Laboratory of Biotechnology of Shaanxi, Northwest University, Xi'an, 710069, Shaanxi, China.; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Life Sciences, Northwest University, Xi'an, 710069, Shaanxi, China.
Xiong Y; College of Life Sciences, Northwest University, Xi'an, 710069, Shaanxi, China. .; Provincial Key Laboratory of Biotechnology of Shaanxi, Northwest University, Xi'an, 710069, Shaanxi, China. .; Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Life Sciences, Northwest University, Xi'an, 710069, Shaanxi, China. .
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Źródło:
Journal of orthopaedic surgery and research [J Orthop Surg Res] 2023 Dec 15; Vol. 18 (1), pp. 968. Date of Electronic Publication: 2023 Dec 15.
Typ publikacji:
Journal Article
MeSH Terms:
Apolipoproteins E*/genetics
Femur Head Necrosis*/genetics
Estrogen Receptor alpha*/genetics
Aged ; Humans ; Case-Control Studies ; Femur Head ; Genetic Predisposition to Disease ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł:
Association of the KISS1 , LIN28B , VDR and ERα gene polymorphisms with early and fast puberty in Chinese girls.
Autorzy:
Li Y; Faculty of Life Science and Biotechnology, Kunming University of Science and Technology, Kunming City, Yunnan Province, China.; Medical School, Kunming University of Science and Technology, Kunming City, Yunnan Province, China.; Department of Pharmacy, Kunming Children's Hospital, Kunming City, Yunnan Province, China.
Zhang H; Department of Clinical Pharmacy, The First People's Hospital of Yunnan Province/the Affiliated Hospital of Kunming University of Science and Technology, Kunming City, Yunnan Province, China.
Li Q; Department of Pharmacy, Kunming Children's Hospital, Kunming City, Yunnan Province, China.
Huang X; Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Kong X; Medical School, Kunming University of Science and Technology, Kunming City, Yunnan Province, China.
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Źródło:
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2023 Dec; Vol. 39 (1), pp. 2181653. Date of Electronic Publication: 2023 Feb 24.
Typ publikacji:
Journal Article
MeSH Terms:
Estrogen Receptor alpha*/genetics
Kisspeptins*/genetics
Puberty*/genetics
Puberty, Precocious*/genetics
Receptors, Calcitriol*/genetics
RNA-Binding Proteins*/genetics
Female ; Humans ; East Asian People ; Follicle Stimulating Hormone, Human ; Gonadotropin-Releasing Hormone/genetics ; Luteinizing Hormone/metabolism ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł:
Mutation of aspartic acid 262 on estrogen receptor abrogates estradiol signaling pathway.
Autorzy:
Xu X; Department of Basic Medical Research, Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Key Laboratory of Cardiovascular Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, P.R. China.; Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, State Key Laboratory of Respiratory Disease, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Yu H; Department of Basic Medical Research, Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Key Laboratory of Cardiovascular Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, P.R. China.; Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, State Key Laboratory of Respiratory Disease, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Zhu S; Department of Basic Medical Research, Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Key Laboratory of Cardiovascular Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, P.R. China.; Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, State Key Laboratory of Respiratory Disease, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Li P; Department of Basic Medical Research, Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Key Laboratory of Cardiovascular Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, P.R. China.; Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, State Key Laboratory of Respiratory Disease, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Li X; Department of Basic Medical Research, Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Key Laboratory of Cardiovascular Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, P.R. China.; Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, State Key Laboratory of Respiratory Disease, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Gao Y; Department of Basic Medical Research, Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Key Laboratory of Cardiovascular Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, P.R. China.; Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, State Key Laboratory of Respiratory Disease, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Xiang Y; Department of Basic Medical Research, Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Key Laboratory of Cardiovascular Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, P.R. China.; Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, State Key Laboratory of Respiratory Disease, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Zhao G; Department of Basic Medical Research, Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Key Laboratory of Cardiovascular Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, P.R. China.; Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, State Key Laboratory of Respiratory Disease, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou, Guangdong, P.R. China.
Simoncini T; Molecular and Cellular Gynecological Endocrinology Laboratory (MCGEL), Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy.
Lin H; Department of Basic Medical Research, Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Key Laboratory of Cardiovascular Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, P.R. China.
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Źródło:
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2023 Dec; Vol. 39 (1), pp. 2250881.
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, Estrogen*
Estrogen Receptor alpha*/genetics
Female ; Animals ; Mice ; Aspartic Acid/pharmacology ; Estradiol/pharmacology ; Estrogens/pharmacology ; Mutation ; Signal Transduction ; Alanine ; Disease Models, Animal ; Estrogen Antagonists
Czasopismo naukowe
Tytuł:
Attenuation of estrogen and its receptors in the post-menopausal stage exacerbates dyslipidemia and leads to cognitive impairment.
Autorzy:
Meng Q; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Chao Y; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Zhang S; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Ding X; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Feng H; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Zhang C; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Liu B; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Zhu W; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Li Y; School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Zhang Q; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Tong H; Department of Pharmacy, Jiangsu Province Hospital of Integrated of Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028, China.
Wu L; Department of Cardiovascular, Jiangsu Province Hospital of Integrated of Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210028, China. .
Bian H; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China. .
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Źródło:
Molecular brain [Mol Brain] 2023 Nov 20; Vol. 16 (1), pp. 80. Date of Electronic Publication: 2023 Nov 20.
Typ publikacji:
Journal Article
MeSH Terms:
Estrogen Receptor alpha*/metabolism
Cognitive Dysfunction*/complications
Humans ; Mice ; Female ; Animals ; Estrogen Receptor beta/metabolism ; Postmenopause ; Estrogens/pharmacology ; Estradiol/pharmacology ; Simvastatin/pharmacology ; Simvastatin/therapeutic use ; Lipids
Czasopismo naukowe
Tytuł:
Endometrial cancer (EC) derived G3BP1 overexpression and mutant promote EC tumorigenesis and metastasis via SPOP/ERα axis.
Autorzy:
Ge Y; Department of Radiotherapy and Chemotherapy, The First Hospital of Ningbo University, Ningbo University, Ningbo, 315010, China.; The Affiliated People's Hospital of Ningbo University, Ningbo, 315040, China.; Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Health Science Center, Medical School of Ningbo University, Ningbo University, Ningbo, 315211, Zhejiang, China.
Jin J; The Affiliated People's Hospital of Ningbo University, Ningbo, 315040, China.
Chen G; Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Health Science Center, Medical School of Ningbo University, Ningbo University, Ningbo, 315211, Zhejiang, China.
Li J; Department of Radiotherapy and Chemotherapy, The First Hospital of Ningbo University, Ningbo University, Ningbo, 315010, China. .; The Affiliated People's Hospital of Ningbo University, Ningbo, 315040, China. .
Ye M; Department of Radiotherapy and Chemotherapy, The First Hospital of Ningbo University, Ningbo University, Ningbo, 315010, China. .; The Affiliated People's Hospital of Ningbo University, Ningbo, 315040, China. .
Jin X; Department of Radiotherapy and Chemotherapy, The First Hospital of Ningbo University, Ningbo University, Ningbo, 315010, China. .; The Affiliated People's Hospital of Ningbo University, Ningbo, 315040, China. .; Department of Biochemistry and Molecular Biology, Zhejiang Key Laboratory of Pathophysiology, Health Science Center, Medical School of Ningbo University, Ningbo University, Ningbo, 315211, Zhejiang, China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2023 Oct 30; Vol. 21 (1), pp. 303. Date of Electronic Publication: 2023 Oct 30.
Typ publikacji:
Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Endometrial Neoplasms*/metabolism
Estrogen Receptor alpha*/metabolism
Female ; Humans ; Male ; Cell Transformation, Neoplastic ; DNA Helicases/genetics ; DNA Helicases/metabolism ; Fulvestrant ; Poly-ADP-Ribose Binding Proteins/genetics ; Poly-ADP-Ribose Binding Proteins/metabolism ; RNA Helicases/genetics ; RNA Helicases/metabolism ; RNA Recognition Motif Proteins/genetics ; RNA Recognition Motif Proteins/metabolism ; Ubiquitination
Czasopismo naukowe
Tytuł:
Withaferin-A attenuates diabetes mellitus induced male reproductive dysfunction mediated by ERα in brain and testes of Swiss albino mice.
Autorzy:
Baghel K; Department of Microbiology, School of Biological Sciences, Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, MP, 470003, India.; Department of Zoology, School of Biological Sciences, Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, MP, 470003, India.
Azam Z; Department of Zoology, School of Biological Sciences, Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, MP, 470003, India.
Srivastava R; Department of Zoology, University of Allahabad, Prayagraj, UP, 211002, India.
Gupta N; Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, MP, 470003, India.
Kango N; Department of Microbiology, School of Biological Sciences, Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, MP, 470003, India. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 17; Vol. 13 (1), pp. 17625. Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Experimental*/complications
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/metabolism
Estrogen Receptor alpha*/metabolism
Withanolides*/pharmacology
Withanolides*/therapeutic use
Animals ; Male ; Mice ; Blood Glucose/metabolism ; Brain/drug effects ; Brain/metabolism ; Gonadotropin-Releasing Hormone/metabolism ; Hydrogen Peroxide/adverse effects ; Streptozocin/adverse effects ; Testis/drug effects ; Testis/metabolism ; Testosterone/adverse effects
Czasopismo naukowe
Tytuł:
Meta-analysis of integrated ChIP-seq and transcriptome data revealed genomic regions affected by estrogen receptor alpha in breast cancer.
Autorzy:
Piryaei Z; Department of Bioinformatics, Kish International Campus University of Tehran, Kish, Iran.; Laboratory of Complex Biological Systems and Bioinformatics (CBB), Department of Bioinformatics, Institute of Biochemistry and Biophysics (IBB), University of Tehran, Tehran, Iran.
Salehi Z; Laboratory of Complex Biological Systems and Bioinformatics (CBB), Department of Bioinformatics, Institute of Biochemistry and Biophysics (IBB), University of Tehran, Tehran, Iran.; Hematology-Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Ebrahimie E; Genomics Research Platform, School of Agriculture, Biomedicine and Environment, La Trobe University, Melbourne, VIC, Australia.
Ebrahimi M; School of Animal and Veterinary Sciences, The University of Adelaide, Adelaide, South Australia, Australia.
Kavousi K; Laboratory of Complex Biological Systems and Bioinformatics (CBB), Department of Bioinformatics, Institute of Biochemistry and Biophysics (IBB), University of Tehran, Tehran, Iran. .
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Źródło:
BMC medical genomics [BMC Med Genomics] 2023 Sep 15; Vol. 16 (1), pp. 219. Date of Electronic Publication: 2023 Sep 15.
Typ publikacji:
Meta-Analysis; Journal Article
MeSH Terms:
Estrogen Receptor alpha*/genetics
Breast Neoplasms*/genetics
Humans ; Female ; Receptors, Estrogen ; Chromatin Immunoprecipitation Sequencing ; Transcriptome ; Genomics ; Estrogens
Czasopismo naukowe
Tytuł:
Differences in Cholesterol Metabolism, Hepato-Intestinal Aging, and Hepatic Endocrine Milieu in Rats as Affected by the Sex and Age.
Autorzy:
Šošić-Jurjević B; Department of Cytology, Institute for Biological Research 'Siniša Stanković'-National Institute of Republic of Serbia, University of Belgrade, Bulevar Despota Stefana 142, 11060 Belgrade, Serbia.
Lütjohann D; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Venusberg-Campus 1, 53127 Bonn, Germany.
Trifunović S; Department of Cytology, Institute for Biological Research 'Siniša Stanković'-National Institute of Republic of Serbia, University of Belgrade, Bulevar Despota Stefana 142, 11060 Belgrade, Serbia.
Pavlović S; Department of Physiology, Institute for Biological Research 'Siniša Stanković'-National Institute of Republic of Serbia, University of Belgrade, Bulevar Despota Stefana 142, 11060 Belgrade, Serbia.
Borković Mitić S; Department of Physiology, Institute for Biological Research 'Siniša Stanković'-National Institute of Republic of Serbia, University of Belgrade, Bulevar Despota Stefana 142, 11060 Belgrade, Serbia.
Jovanović L; Department of Pathology and Medical Cytology, University Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Dr. Koste Todorovića 26, 11000 Belgrade, Serbia.
Ristić N; Department of Cytology, Institute for Biological Research 'Siniša Stanković'-National Institute of Republic of Serbia, University of Belgrade, Bulevar Despota Stefana 142, 11060 Belgrade, Serbia.
Marina L; National Centre for Infertility and Endocrinology of Gender, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Faculty of Medicine, University of Belgrade, Koste Todorovića 6, 11000 Belgrade, Serbia.
Ajdžanović V; Department of Cytology, Institute for Biological Research 'Siniša Stanković'-National Institute of Republic of Serbia, University of Belgrade, Bulevar Despota Stefana 142, 11060 Belgrade, Serbia.
Filipović B; Department of Cytology, Institute for Biological Research 'Siniša Stanković'-National Institute of Republic of Serbia, University of Belgrade, Bulevar Despota Stefana 142, 11060 Belgrade, Serbia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 10; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 10.
Typ publikacji:
Journal Article
MeSH Terms:
Estrogen Receptor alpha*
Liver*
Female ; Male ; Rats ; Animals ; Catalase/genetics ; Rats, Wistar ; Aging
Czasopismo naukowe
Tytuł:
Vomeronasal Receptors Associated with Circulating Estrogen Processing Chemosensory Cues in Semi-Aquatic Mammals.
Autorzy:
Xie W; Laboratory of Animal Physiology, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.
Chen M; Laboratory of Animal Physiology, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.
Shen Y; Laboratory of Animal Physiology, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.
Liu Y; Laboratory of Animal Physiology, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.
Zhang H; Laboratory of Animal Physiology, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.
Weng Q; Laboratory of Animal Physiology, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 27; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 27.
Typ publikacji:
Journal Article
MeSH Terms:
Estrogen Receptor alpha*/genetics
Estrogen Receptor alpha*/metabolism
Vomeronasal Organ*/metabolism
Animals ; Female ; Estrogen Receptor beta/genetics ; Estrogen Receptor beta/metabolism ; Cues ; Mammals/metabolism ; Estrogens/metabolism ; Arvicolinae
Czasopismo naukowe
Tytuł:
Expression Analysis of Lipocalin 2 (LCN2) in Reproductive and Non-Reproductive Tissues of Esr1 -Deficient Mice.
Autorzy:
Kessel JC; Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), RWTH University Hospital Aachen, D-52074 Aachen, Germany.
Weiskirchen R; Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), RWTH University Hospital Aachen, D-52074 Aachen, Germany.
Schröder SK; Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), RWTH University Hospital Aachen, D-52074 Aachen, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 25; Vol. 24 (11). Date of Electronic Publication: 2023 May 25.
Typ publikacji:
Journal Article
MeSH Terms:
Adipose Tissue*/metabolism
Estrogen Receptor alpha*/genetics
Estrogen Receptor alpha*/metabolism
Animals ; Female ; Male ; Mice ; Lipocalin-2/genetics ; Lipocalin-2/metabolism ; Mice, Knockout ; Ovary/metabolism ; Testis/metabolism
Czasopismo naukowe
Tytuł:
The role of mesenchymal estrogen receptor 1 in mouse uterus in response to estrogen.
Autorzy:
Furuminato K; Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, Niijuku 6-3-1, Katsushika, Tokyo, 125-8585, Japan.
Minatoya S; Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, Niijuku 6-3-1, Katsushika, Tokyo, 125-8585, Japan.
Senoo E; Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, Niijuku 6-3-1, Katsushika, Tokyo, 125-8585, Japan.
Goto T; Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, Niijuku 6-3-1, Katsushika, Tokyo, 125-8585, Japan.
Yamazaki S; Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, Niijuku 6-3-1, Katsushika, Tokyo, 125-8585, Japan.
Sakaguchi M; Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, Niijuku 6-3-1, Katsushika, Tokyo, 125-8585, Japan.
Toyota K; Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, Niijuku 6-3-1, Katsushika, Tokyo, 125-8585, Japan.; Noto Marine Laboratory, Institute of Nature and Environmental Technology, Kanazawa University, Noto, Ishikawa, 927-0552, Japan.
Iguchi T; Graduate School of Nanobioscience, Yokohama City University, Yokohama, Kanagawa, 236-0027, Japan.
Miyagawa S; Department of Biological Science and Technology, Faculty of Advanced Engineering, Tokyo University of Science, Niijuku 6-3-1, Katsushika, Tokyo, 125-8585, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 29; Vol. 13 (1), pp. 12293. Date of Electronic Publication: 2023 Jul 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Estrogen Receptor alpha*/genetics
Craniocerebral Trauma*
Female ; Animals ; Mice ; Receptors, Estrogen/genetics ; Estrogens/pharmacology ; Uterus
Czasopismo naukowe
Tytuł:
Membrane estrogen receptor α signaling modulates the sensitivity to estradiol treatment in a dose- and tissue- dependent manner.
Autorzy:
Jiang Y; Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Vita Stråket 11, S-413 45, Göteborg, Sweden.
Horkeby K; Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Vita Stråket 11, S-413 45, Göteborg, Sweden. .
Henning P; Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Vita Stråket 11, S-413 45, Göteborg, Sweden.
Wu J; Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Vita Stråket 11, S-413 45, Göteborg, Sweden.
Lawenius L; Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Vita Stråket 11, S-413 45, Göteborg, Sweden.
Engdahl C; Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Vita Stråket 11, S-413 45, Göteborg, Sweden.; Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
Gupta P; Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Vita Stråket 11, S-413 45, Göteborg, Sweden.; Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
Movérare-Skrtic S; Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Vita Stråket 11, S-413 45, Göteborg, Sweden.
Nilsson KH; Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Vita Stråket 11, S-413 45, Göteborg, Sweden.
Levin E; Division of Endocrinology, Department of Medicine, University of California, Irvine, Irvine, CA, 92697, USA.; Department of Veterans Affairs Medical Center, Long Beach, Long Beach, CA, 90822, USA.
Ohlsson C; Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Vita Stråket 11, S-413 45, Göteborg, Sweden.; Department of Drug Treatment, Sahlgrenska University Hospital, Region Västra Götaland, Gothenburg, Sweden.
Lagerquist MK; Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Vita Stråket 11, S-413 45, Göteborg, Sweden.
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Źródło:
Scientific reports [Sci Rep] 2023 Jun 03; Vol. 13 (1), pp. 9046. Date of Electronic Publication: 2023 Jun 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Estrogen Receptor alpha*/genetics
Estradiol*/pharmacology
Female ; Mice ; Animals ; Humans ; Bone and Bones ; Signal Transduction ; Bone Density ; Uterus ; Ovariectomy
Czasopismo naukowe
Tytuł:
Isoflavones Mediate Dendritogenesis Mainly through Estrogen Receptor α.
Autorzy:
Ariyani W; Metabolic Signal Research Center, Institute for Molecular and Cellular Regulation, Gunma University, 3-39-15 Showa-machi, Maebashi 371-8512, Japan.; Department of Integrative Physiology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi 371-8511, Japan.
Amano I; Department of Integrative Physiology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi 371-8511, Japan.
Koibuchi N; Department of Integrative Physiology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi 371-8511, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 19; Vol. 24 (10). Date of Electronic Publication: 2023 May 19.
Typ publikacji:
Journal Article
MeSH Terms:
Estrogen Receptor alpha*/genetics
Isoflavones*/pharmacology
Animals ; Mice ; Fulvestrant ; Genistein/pharmacology ; Receptors, Estrogen/genetics ; Receptors, Estrogen/metabolism ; Estrogen Receptor beta/metabolism ; Estradiol/pharmacology ; Estrogens
Czasopismo naukowe
Tytuł:
Butyrate mitigates metabolic dysfunctions via the ERα-AMPK pathway in muscle in OVX mice with diet-induced obesity.
Autorzy:
Fu Q; Department of Medical Experiment Center, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Qingdao, 266035, Shandong, China.; Department of Qingdao Key Lab of Mitochondrial Medicine, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, 266035, Shandong, China.
Li T; Institute of Biomedical Engineering, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, 610041, China.
Zhang C; Department of Medical Experiment Center, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Qingdao, 266035, Shandong, China.; Department of Qingdao Key Lab of Mitochondrial Medicine, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, 266035, Shandong, China.
Ma X; Department of Medical Experiment Center, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Qingdao, 266035, Shandong, China.; Department of Qingdao Key Lab of Mitochondrial Medicine, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, 266035, Shandong, China.
Meng L; Department of Medical Experiment Center, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Qingdao, 266035, Shandong, China.; Department of Qingdao Key Lab of Mitochondrial Medicine, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, 266035, Shandong, China.
Liu L; Department of Medical Experiment Center, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Qingdao, 266035, Shandong, China.; Department of Qingdao Key Lab of Mitochondrial Medicine, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, 266035, Shandong, China.
Shao K; Department of Medical Experiment Center, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Qingdao, 266035, Shandong, China.; Department of Qingdao Key Lab of Mitochondrial Medicine, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, 266035, Shandong, China.
Wu G; Department of Medical Experiment Center, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Qingdao, 266035, Shandong, China.; Department of Qingdao Key Lab of Mitochondrial Medicine, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, 266035, Shandong, China.
Zhu X; Department of Pathology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, 266035, Shandong, China.
Zhao X; Department of Medical Experiment Center, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, 758 Hefei Road, Qingdao, 266035, Shandong, China. .; Department of Qingdao Key Lab of Mitochondrial Medicine, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, 266035, Shandong, China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2023 May 04; Vol. 21 (1), pp. 95. Date of Electronic Publication: 2023 May 04.
Typ publikacji:
Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Estrogen Receptor alpha*/metabolism
Metabolic Syndrome*/drug therapy
Mice ; Female ; Animals ; AMP-Activated Protein Kinases/metabolism ; Muscle, Skeletal/metabolism ; Diet, High-Fat ; Obesity/drug therapy ; Obesity/metabolism ; Butyric Acid/metabolism ; Butyric Acid/pharmacology ; Butyric Acid/therapeutic use ; Receptors, Estrogen/metabolism ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
Estrogen Receptor Alpha Splice Variants, Post-Translational Modifications, and Their Physiological Functions.
Autorzy:
Saito K; Department of Neuroscience and Pharmacology, Carver College of Medicine, The University of Iowa, Iowa City, IA 52241, USA.
Cui H; Department of Neuroscience and Pharmacology, Carver College of Medicine, The University of Iowa, Iowa City, IA 52241, USA.; Iowa Neuroscience Institute, Carver College of Medicine, The University of Iowa, Iowa City, IA 52241, USA.; F.O.E. Diabetes Research Center, Carver College of Medicine, The University of Iowa, Iowa City, IA 52241, USA.
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Źródło:
Cells [Cells] 2023 Mar 14; Vol. 12 (6). Date of Electronic Publication: 2023 Mar 14.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural
MeSH Terms:
Estrogen Receptor alpha*/genetics
Estrogen Receptor alpha*/metabolism
Protein Processing, Post-Translational*/physiology
Animals ; Mice ; Alternative Splicing/genetics ; Exons ; Protein Isoforms/genetics ; Protein Isoforms/metabolism
Czasopismo naukowe
Tytuł:
Blocking the Hormone Receptors Modulates NLRP3 in LPS-Primed Breast Cancer Cells.
Autorzy:
Hamza S; Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.
Garanina EE; Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.
Alsaadi M; Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.
Khaiboullina SF; Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.
Tezcan G; Institute of Fundamental Medicine and Biology, Kazan Federal University, 420008 Kazan, Russia.; Department of Fundamental Sciences, Faculty of Dentistry, Bursa Uludag University, Bursa 16059, Turkey.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 02; Vol. 24 (5). Date of Electronic Publication: 2023 Mar 02.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/metabolism
Breast Neoplasms*/pathology
NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism
Tamoxifen*/pharmacology
Estrogen Receptor alpha*/antagonists & inhibitors
Estrogen Receptor alpha*/metabolism
Estrogen Antagonists*/pharmacology
Female ; Humans ; Adenosine Triphosphate/metabolism ; Interleukin-8/metabolism ; Lipopolysaccharides ; MCF-7 Cells ; Receptors, Progesterone/antagonists & inhibitors ; Receptor, ErbB-2/antagonists & inhibitors
Czasopismo naukowe
Tytuł:
Proteomic profiling reveals that ESR1 mutations enhance cyclin-dependent kinase signaling.
Autorzy:
De Marchi T; Division of Surgery, Oncology, and Pathology, Department of Clinical Sciences, Lund University, Solvegatan 19, 22362, Lund, Sweden. tommaso.de_.
Lai CF; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.
Simmons GM; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.
Goldsbrough I; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.
Harrod A; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.
Lam T; Division of Surgery, Oncology, and Pathology, Department of Clinical Sciences, Lund University, Solvegatan 19, 22362, Lund, Sweden.
Buluwela L; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.
Kjellström S; Department of Biochemistry and Structural Biology, Center for Molecular Protein Science, Lund University, Solvegatan 19, 22362, Lund, Sweden.; Swedish National Infrastructure for Biological Mass Spectrometry - BioMS, Lund, Sweden.
Brueffer C; Division of Oncology, Department of Clinical Sciences Lund, Lund University, Medicon Village, 22381, Lund, Sweden.
Saal LH; Division of Oncology, Department of Clinical Sciences Lund, Lund University, Medicon Village, 22381, Lund, Sweden.
Malmström J; Division of Infection Medicine, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Klinikgatan 32, 22184, Lund, Sweden.
Ali S; Department of Surgery and Cancer, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK. .
Niméus E; Division of Surgery, Oncology, and Pathology, Department of Clinical Sciences, Lund University, Solvegatan 19, 22362, Lund, Sweden. .; Department of Surgery, Skåne University Hospital, Lund, Sweden. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 22; Vol. 14 (1), pp. 6873. Date of Electronic Publication: 2024 Mar 22.
Typ publikacji:
Journal Article
MeSH Terms:
Cyclin-Dependent Kinases*/genetics
Breast Neoplasms*/pathology
Humans ; Female ; Proteome/genetics ; Proteomics ; Estrogen Receptor alpha/genetics ; Estrogen Receptor alpha/metabolism ; Mutation ; Estrogens ; Receptors, Estrogen/genetics ; Phosphoproteins/genetics
Czasopismo naukowe
Tytuł:
Linking alterations in estrogen receptor expression to memory deficits and depressive behavior in an ovariectomy mouse model.
Autorzy:
Baek DC; Institute of Bioscience & Integrative Medicine, Daejeon Korean Hospital of Daejeon University, Daedukdae-ro 176 bun-gil 75, Daejeon, 35235, Republic of Korea.
Kang JY; Institute of Bioscience & Integrative Medicine, Daejeon Korean Hospital of Daejeon University, Daedukdae-ro 176 bun-gil 75, Daejeon, 35235, Republic of Korea.
Lee JS; Institute of Bioscience & Integrative Medicine, Daejeon Korean Hospital of Daejeon University, Daedukdae-ro 176 bun-gil 75, Daejeon, 35235, Republic of Korea.
Lee EJ; Department of Korean Rehabilitation Medicine, Daejeon Korean Hospital of Daejeon University, Daedukdae-ro 176 bun-gil 75, Daejeon, 35235, Republic of Korea.
Son CG; Institute of Bioscience & Integrative Medicine, Daejeon Korean Hospital of Daejeon University, Daedukdae-ro 176 bun-gil 75, Daejeon, 35235, Republic of Korea. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 21; Vol. 14 (1), pp. 6854. Date of Electronic Publication: 2024 Mar 21.
Typ publikacji:
Journal Article
MeSH Terms:
Estrogen Receptor beta*/genetics
Estrogen Receptor beta*/metabolism
Receptors, Estrogen*/metabolism
Animals ; Female ; Humans ; Mice ; Estradiol/metabolism ; Estrogen Receptor alpha/genetics ; Estrogen Receptor alpha/metabolism ; Estrogens/metabolism ; Hippocampus/metabolism ; Memory Disorders/etiology ; Memory Disorders/metabolism ; Mice, Inbred C57BL ; Ovariectomy
Czasopismo naukowe
Tytuł:
EB1089 Increases the Antiproliferative Response of Lapatinib in Combination with Antiestrogens in HER2-Positive Breast Cancer Cells.
Autorzy:
Achounna AS; Departamento de Biología Molecular y Biotecnología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
Ordaz-Rosado D; Departamento de Biología de la Reproducción Dr. Carlos Gual Castro, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Belisario Domínguez Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.
García-Quiroz J; Departamento de Biología de la Reproducción Dr. Carlos Gual Castro, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Belisario Domínguez Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.
Morales-Guadarrama G; Departamento de Biología de la Reproducción Dr. Carlos Gual Castro, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Belisario Domínguez Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.
Milo-Rocha E; Departamento de Biología Molecular y Biotecnología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
Larrea F; Departamento de Biología de la Reproducción Dr. Carlos Gual Castro, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Belisario Domínguez Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.
Díaz L; Departamento de Biología de la Reproducción Dr. Carlos Gual Castro, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga No. 15, Belisario Domínguez Sección XVI, Tlalpan, Ciudad de México 14080, Mexico.
García-Becerra R; Departamento de Biología Molecular y Biotecnología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.; Programa de Investigación de Cáncer de Mama, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 09; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Breast Neoplasms*/metabolism
Calcitriol/*analogs & derivatives
Humans ; Female ; Lapatinib/pharmacology ; Lapatinib/therapeutic use ; Calcitriol/pharmacology ; Estrogen Receptor alpha/genetics ; Estrogen Receptor alpha/metabolism ; Estrogen Receptor Modulators/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; Receptor, ErbB-2/metabolism ; Estrogen Antagonists/therapeutic use ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
ERK1/2-RSK regulation of oestrogen homeostasis.
Autorzy:
Wright EB; Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
Lannigan DA; Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.; Pathology, Microbiology & Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.; Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA.
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Źródło:
The FEBS journal [FEBS J] 2023 Apr; Vol. 290 (8), pp. 1943-1953. Date of Electronic Publication: 2022 Feb 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:
Breast Neoplasms*/metabolism
Estrogen Receptor alpha*/genetics
Estrogen Receptor alpha*/metabolism
Female ; Humans ; Pregnancy ; Estrogens ; Hedgehog Proteins/metabolism ; MAP Kinase Signaling System ; Receptors, Estrogen/genetics ; Receptors, Estrogen/metabolism
Czasopismo naukowe
Tytuł:
Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment.
Autorzy:
Gobbi S; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Martini S; Molecular Pharmacology Unit, Fondazione IRCSS Istituto Nazionale dei Tumori, Via Amadeo 42, 20113 Milano, Italy.
Rozza R; National Research Council of Italy Institute of Materials (CNR-IOM) c/o SISSA, Via Bonomea 265, 34136 Trieste, Italy.
Spinello A; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, Viale delle Scienze, 90128 Palermo, Italy.
Caciolla J; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Rampa A; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Belluti F; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
Zaffaroni N; Molecular Pharmacology Unit, Fondazione IRCSS Istituto Nazionale dei Tumori, Via Amadeo 42, 20113 Milano, Italy.
Magistrato A; National Research Council of Italy Institute of Materials (CNR-IOM) c/o SISSA, Via Bonomea 265, 34136 Trieste, Italy.
Bisi A; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Mar 29; Vol. 28 (7). Date of Electronic Publication: 2023 Mar 29.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Breast Neoplasms*/enzymology
Breast Neoplasms*/metabolism
Aromatase Inhibitors*/chemical synthesis
Aromatase Inhibitors*/chemistry
Aromatase Inhibitors*/pharmacology
Flavonoids*/chemical synthesis
Flavonoids*/chemistry
Flavonoids*/pharmacology
Drug Design*
Estrogen Receptor alpha*/antagonists & inhibitors
Estrogen Receptor alpha*/chemistry
Estrogen Receptor alpha*/metabolism
Aromatase*/chemistry
Aromatase*/metabolism
Humans ; Female ; Molecular Dynamics Simulation ; Thermodynamics ; Inhibitory Concentration 50 ; Molecular Docking Simulation
Czasopismo naukowe

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