Skocz do pozycji: 1.

Tytuł:

A Novel Method of Magnetic Nanoparticles Functionalized with Anti-Folate Receptor Antibody and Methotrexate for Antibody Mediated Targeted Drug Delivery.

Autorzy:

Lodhi MS; School of Biochemistry and Biotechnology, University of the Punjab, Lahore 54890, Pakistan.; Institute of molecular Biology and Biotechnology, The University of Lahore, Lahore 58810, Pakistan.
Khalid F; School of Biochemistry and Biotechnology, University of the Punjab, Lahore 54890, Pakistan.
Khan MT; Institute of molecular Biology and Biotechnology, The University of Lahore, Lahore 58810, Pakistan.
Samra ZQ; School of Biochemistry and Biotechnology, University of the Punjab, Lahore 54890, Pakistan.
Muhammad S; Department of Physics, College of Science, King Khalid University, Abha 61413, Saudi Arabia.
Zhang YJ; College of Life Sciences, Chongqing Normal University, Shapingba, Chongqing 401331, China.
Mou K; Department of Neurosurgery, Bishan Hospital of Chongqing, Chongqing 402760, China.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2022 Jan 01; Vol. 27 (1). Date of Electronic Publication: 2022 Jan 01.

Typ publikacji:

Journal Article

MeSH Terms:

Antibodies*/chemistry
Antibodies*/pharmacology
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Drug Delivery Systems*
Magnetite Nanoparticles*/chemistry
Magnetite Nanoparticles*/therapeutic use
Methotrexate*/chemistry
Methotrexate*/pharmacology
Nanocomposites*/chemistry
Nanocomposites*/therapeutic use
Folate Receptors, GPI-Anchored/*antagonists & inhibitors
Animals ; Folate Receptors, GPI-Anchored/immunology ; HeLa Cells ; Humans ; Rabbits

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 2.

Tytuł:

Preparation and Evaluation of Novel Folate Isonitrile Tc Complexes as Potential Tumor Imaging Agents to Target Folate Receptors.

Autorzy:

Feng J; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.; NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Perking University, Beijing 100091, China.
Zhang X; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.; NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Perking University, Beijing 100091, China.
Ruan Q; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.; NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Perking University, Beijing 100091, China.
Jiang Y; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.; NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Perking University, Beijing 100091, China.
Zhang J; Key Laboratory of Radiopharmaceuticals of Ministry of Education, College of Chemistry, Beijing Normal University, Beijing 100875, China.; NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Perking University, Beijing 100091, China.

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Źródło:

Molecules (Basel, Switzerland) [Molecules] 2021 Jul 28; Vol. 26 (15). Date of Electronic Publication: 2021 Jul 28.

Typ publikacji:

Journal Article

MeSH Terms:

Diagnostic Imaging/*methods
Folate Receptors, GPI-Anchored/*metabolism
Folic Acid/*chemistry
Kidney/*diagnostic imaging
Nitriles/*chemistry
Radiopharmaceuticals/*chemical synthesis
Tomography, Emission-Computed, Single-Photon/*methods
Animals ; Binding, Competitive ; Drug Stability ; Folate Receptors, GPI-Anchored/genetics ; Folic Acid/pharmacokinetics ; Gene Expression ; Humans ; Hydrophobic and Hydrophilic Interactions ; KB Cells ; Kidney/metabolism ; Mice ; Protein Binding ; Radiopharmaceuticals/pharmacokinetics ; Technetium/chemistry ; Tissue Distribution

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 3.

Tytuł:

Final analysis of a phase I/IIa trial of the folate-binding protein-derived E39 peptide vaccine to prevent recurrence in ovarian and endometrial cancer patients.

Autorzy:

Brown TA; Department of Surgery, San Antonio Military Medical Center, San Antonio, Texas.
Byrd K; National Capital Consortium Fellowship in Gynecologic Oncology, Walter Reed National Military Medical Center Bethesda, Bethesda, Maryland.
Vreeland TJ; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Clifton GT; Department of Surgery, San Antonio Military Medical Center, San Antonio, Texas.
Jackson DO; Department of Surgery, San Antonio Military Medical Center, San Antonio, Texas.
Hale DF; Department of Surgery, San Antonio Military Medical Center, San Antonio, Texas.
Herbert GS; Department of Surgery, San Antonio Military Medical Center, San Antonio, Texas.
Myers JW; Department of Surgery, San Antonio Military Medical Center, San Antonio, Texas.
Greene JM; Department of Surgery, San Antonio Military Medical Center, San Antonio, Texas.
Berry JS; Department of Surgery, Womack Army Medical Center, Fayetteville, North Carolina.
Martin J; Cancer Vaccine Development Program, San Antonio, Texas.
Elkas JC; Department of Obstetrics and Gynecology, Inova Fairfax Hospital, Annandale, Virginia.; Mid-Atlantic Gynecologic Oncology and Pelvic Surgical Associates, Annandale, Virginia.
Conrads TP; National Capital Consortium Fellowship in Gynecologic Oncology, Walter Reed National Military Medical Center Bethesda, Bethesda, Maryland.; Department of Obstetrics and Gynecology, Inova Fairfax Hospital, Annandale, Virginia.; Inova Health System, Inova Schar Cancer Institute, Annandale, Virginia.
Darcy KM; National Capital Consortium Fellowship in Gynecologic Oncology, Walter Reed National Military Medical Center Bethesda, Bethesda, Maryland.
Hamilton CA; National Capital Consortium Fellowship in Gynecologic Oncology, Walter Reed National Military Medical Center Bethesda, Bethesda, Maryland.
Maxwel GL; National Capital Consortium Fellowship in Gynecologic Oncology, Walter Reed National Military Medical Center Bethesda, Bethesda, Maryland.; Department of Obstetrics and Gynecology, Inova Fairfax Hospital, Annandale, Virginia.; Inova Health System, Inova Schar Cancer Institute, Annandale, Virginia.
Peoples GE; Department of Obstetrics and Gynecology, Inova Fairfax Hospital, Annandale, Virginia.

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Źródło:

Cancer medicine [Cancer Med] 2019 Aug; Vol. 8 (10), pp. 4678-4687. Date of Electronic Publication: 2019 Jul 05.

Typ publikacji:

Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, Non-P.H.S.

MeSH Terms:

Cancer Vaccines/*administration & dosage
Endometrial Neoplasms/*prevention & control
Folate Receptors, GPI-Anchored/*chemistry
Neoplasm Recurrence, Local/*prevention & control
Ovarian Neoplasms/*prevention & control
Vaccines, Subunit/*administration & dosage
Aged ; Cancer Vaccines/immunology ; Dose-Response Relationship, Drug ; Endometrial Neoplasms/immunology ; Female ; Folate Receptors, GPI-Anchored/immunology ; Granulocyte-Macrophage Colony-Stimulating Factor/administration & dosage ; Granulocyte-Macrophage Colony-Stimulating Factor/immunology ; HLA-A2 Antigen/metabolism ; Humans ; Immunization, Secondary ; Middle Aged ; Neoplasm Recurrence, Local/immunology ; Ovarian Neoplasms/immunology ; Prospective Studies ; Survival Analysis ; Treatment Outcome ; Vaccines, Subunit/immunology

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 4.

Tytuł:

Enhancement of Binding Affinity of Folate to Its Receptor by Peptide Conjugation.

Autorzy:

Dharmatti R; Nano Medical Engineering Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan. .; Department of Computer Science, School of Computing, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan. .
Miyatake H; Nano Medical Engineering Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan. .
Nandakumar A; Emergent Bioengineering Materials Research Team, RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan. .
Ueda M; Nano Medical Engineering Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan. .; Emergent Bioengineering Materials Research Team, RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan. .
Kobayashi K; Nano Medical Engineering Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan. .
Kiga D; Department of Computer Science, School of Computing, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan. .; Department of Electrical Engineering and Bioscience, Waseda University, 2-2 Wakamatsu Cho, Shinjyuku-ku, Tokyo,162-8480, Japan. .
Yamamura M; Department of Computer Science, School of Computing, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan. .
Ito Y; Nano Medical Engineering Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan. .; Department of Computer Science, School of Computing, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan. .; Emergent Bioengineering Materials Research Team, RIKEN Center for Emergent Matter Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan. .

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2019 Apr 30; Vol. 20 (9). Date of Electronic Publication: 2019 Apr 30.

Typ publikacji:

Journal Article

MeSH Terms:

Folate Receptors, GPI-Anchored/*metabolism
Folic Acid/*analogs & derivatives
Alkynes/chemistry ; Azides/chemistry ; Click Chemistry/methods ; Cyclooctanes/chemistry ; Folate Receptors, GPI-Anchored/chemistry ; Folic Acid/metabolism ; Molecular Docking Simulation ; Peptides/chemistry ; Phenylalanine/analogs & derivatives ; Phenylalanine/chemistry ; Propanols/chemistry ; Protein Binding

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 5.

Tytuł:

Folic acid modified copper nanoclusters for fluorescent imaging of cancer cells with over-expressed folate receptor.

Autorzy:

Xia JM; Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang, 110819, China.
Wei X; Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang, 110819, China.
Chen XW; Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang, 110819, China.
Shu Y; Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang, 110819, China. .
Wang JH; Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang, 110819, China. .

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Źródło:

Mikrochimica acta [Mikrochim Acta] 2018 Mar 03; Vol. 185 (3), pp. 205. Date of Electronic Publication: 2018 Mar 03.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Copper/*chemistry
Folate Receptors, GPI-Anchored/*genetics
Folic Acid/*chemistry
Nanostructures/*chemistry
Optical Imaging/*methods
A549 Cells ; Biological Transport ; Folate Receptors, GPI-Anchored/metabolism ; Folic Acid/metabolism ; Gene Expression ; HeLa Cells ; Humans ; Water/chemistry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 6.

Tytuł:

Accessing Structurally Diverse Near-Infrared Cyanine Dyes for Folate Receptor-Targeted Cancer Cell Staining.

Autorzy:

König SG; Institute of Inorganic Chemistry, Heidelberg University, Im Neuenheimer Feld 274, 69120, Heidelberg, Germany.
Krämer R; Institute of Inorganic Chemistry, Heidelberg University, Im Neuenheimer Feld 274, 69120, Heidelberg, Germany.

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Źródło:

Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2017 Jul 12; Vol. 23 (39), pp. 9306-9312. Date of Electronic Publication: 2017 May 15.

Typ publikacji:

Journal Article

MeSH Terms:

Carbocyanines/*chemistry
Folate Receptors, GPI-Anchored/*metabolism
Cell Line ; Fluorescent Dyes/chemistry ; Folate Receptors, GPI-Anchored/chemistry ; HeLa Cells ; Humans ; Light ; Microscopy, Fluorescence ; Spectrophotometry, Ultraviolet

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 7.

Tytuł:

Redox-Sensitive and Folate-Receptor-Mediated Targeting of Cervical Cancer Cells for Photodynamic Therapy Using Nanophotosensitizers Composed of Chlorin e6-Conjugated β-Cyclodextrin via Diselenide Linkage.

Autorzy:

Kim H; Department of Medicine, Graduate School, Dongguk University, Gyeongju 38067, Korea.
Kim MW; Department of Anesthesiology and Pain Medicine, College of Medicine, Dongguk University, Gyeongju 38067, Korea.
Jeong YI; Research Institute of Convergence of Biomedical Sciences, Pusan National University Yangsan Hospital, Gyeongnam 50612, Korea.; The Institute of Dental Science, Chosun University, Gwangju 61452, Korea.
Yang HS; Department of Obstetrics and Gynecology, Dongguk University College of Medicine, Gyeongju 38067, Korea.

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Źródło:

Cells [Cells] 2021 Aug 25; Vol. 10 (9). Date of Electronic Publication: 2021 Aug 25.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Folate Receptors, GPI-Anchored/*metabolism
Nanoparticles/*administration & dosage
Oxidation-Reduction/*drug effects
Photosensitizing Agents/*pharmacology
Porphyrins/*pharmacology
Uterine Cervical Neoplasms/*drug therapy
beta-Cyclodextrins/*pharmacology
Animals ; Cell Line ; Cell Line, Tumor ; Chlorophyllides ; Female ; Folic Acid/metabolism ; HeLa Cells ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Particle Size ; Photochemotherapy/methods ; Uterine Cervical Neoplasms/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 8.

Tytuł:

Targeted Nanoparticles for Fluorescence Imaging of Folate Receptor Positive Tumors.

Autorzy:

Marko AJ; Photodynamic Therapy Center, Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.; Photolitec, LLC, Buffalo, NY 14203, USA.
Borah BM; Photolitec, LLC, Buffalo, NY 14203, USA.
Siters KE; Photolitec, LLC, Buffalo, NY 14203, USA.
Missert JR; Photodynamic Therapy Center, Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Gupta A; Photodynamic Therapy Center, Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Pera P; Photodynamic Therapy Center, Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.
Isaac-Lam MF; Department of Chemistry and Physics, Purdue University Northwest, Westville, IN 46391, USA.
Pandey RK; Photodynamic Therapy Center, Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Buffalo, NY 14263, USA.

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Źródło:

Biomolecules [Biomolecules] 2020 Dec 09; Vol. 10 (12). Date of Electronic Publication: 2020 Dec 09.

Typ publikacji:

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

MeSH Terms:

Breast Neoplasms/*diagnostic imaging
Folate Receptors, GPI-Anchored/*metabolism
Folic Acid/*chemistry
Nanoparticles/*chemistry
Optical Imaging/*methods
Acrylic Resins/chemistry ; Animals ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Carbocyanines/chemistry ; Carbocyanines/metabolism ; Cell Line, Tumor ; Female ; Fibroblasts/metabolism ; Fibrosarcoma/pathology ; Fluorescent Dyes/chemistry ; Fluorescent Dyes/metabolism ; Folic Acid/metabolism ; Glycoconjugates/chemistry ; Glycoconjugates/metabolism ; Heterografts ; Humans ; Infrared Rays ; KB Cells ; Mice ; Mice, Nude

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 9.

Tytuł:

Adjudin-loaded redox-sensitive paclitaxel-prodrug micelles for overcoming multidrug resistance with efficient targeted Colon cancer therapy.

Autorzy:

Chen D; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Ge S; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Zuo L; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Wang S; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Liu M; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Li S; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.

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Źródło:

Drug delivery [Drug Deliv] 2020 Dec; Vol. 27 (1), pp. 1094-1105.

Typ publikacji:

Journal Article

MeSH Terms:

Micelles*
Prodrugs*
Colonic Neoplasms/*drug therapy
Drug Resistance, Neoplasm/*drug effects
Hydrazines/*administration & dosage
Hydrazines/*pharmacology
Indazoles/*administration & dosage
Indazoles/*pharmacology
Paclitaxel/*administration & dosage
Paclitaxel/*pharmacology
Animals ; Dextrins ; Drug Delivery Systems ; Drug Resistance, Multiple/drug effects ; Folate Receptors, GPI-Anchored ; Glutathione ; Humans ; In Vitro Techniques ; Mice ; Oxidation-Reduction ; Xenograft Model Antitumor Assays

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 10.

Tytuł:

Folic acid-modified celastrol nanoparticles: synthesis, characterization, anticancer activity in 2D and 3D breast cancer models.

Autorzy:

Law S; Key Laboratory of Molecular Target and Clinical Pharmacology, State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences and Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong.; Department of Science, School of Science and Technology, The Open University of Hong Kong, Kowloon, Hong Kong.
Leung AW; Asia-Pacific Institute of Aging Studies, Lingnan University, Hong Kong, China.
Xu C; Key Laboratory of Molecular Target and Clinical Pharmacology, State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences and Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.

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Źródło:

Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2020 Dec; Vol. 48 (1), pp. 542-559.

Typ publikacji:

Journal Article

MeSH Terms:

Breast Neoplasms*/drug therapy
Breast Neoplasms*/pathology
Antineoplastic Agents/*pharmacology
Folic Acid/*chemistry
Metal Nanoparticles/*chemistry
Triterpenes/*chemistry
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/metabolism ; Apoptosis/drug effects ; Capsules ; Cell Survival/drug effects ; Drug Stability ; Folate Receptors, GPI-Anchored/metabolism ; Folic Acid/metabolism ; Folic Acid/pharmacology ; Gold/chemistry ; Gold/pharmacology ; Humans ; MCF-7 Cells ; Metal Nanoparticles/toxicity ; Molecular Structure ; Particle Size ; Pentacyclic Triterpenes ; Polymers/chemistry ; Polymers/pharmacology ; Solubility ; Spheroids, Cellular/drug effects ; Triterpenes/pharmacology

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 11.

Tytuł:

The Interplay between Fe 3 O 4 Superparamagnetic Nanoparticles, Sodium Butyrate, and Folic Acid for Intracellular Transport.

Autorzy:

Cambria MT; Dipartimento di Scienze Biomediche e Biotecnologiche, Università di Catania, 95125 Catania, Italy.
Villaggio G; Dipartimento di Scienze Biomediche e Biotecnologiche, Università di Catania, 95125 Catania, Italy.
Laudani S; Dipartimento di Scienze Biomediche e Biotecnologiche, Università di Catania, 95125 Catania, Italy.
Pulvirenti L; Dipartimento di Scienze Chimiche, Università di Catania, 95125 Catania, Italy.
Federico C; Dipartimento di Scienze Geologiche, Biologiche e Ambientali, Università di Catania, 95125 Catania, Italy.
Saccone S; Dipartimento di Scienze Geologiche, Biologiche e Ambientali, Università di Catania, 95125 Catania, Italy.
Condorelli GG; Dipartimento di Scienze Chimiche, Università di Catania, 95125 Catania, Italy.; Consorzio Interuniversitario di Scienza e Tecnologia dei Materiali (INSTM) UdR di Catania, 95125 Catania, Italy.
Sinatra F; Dipartimento di Scienze Biomediche e Biotecnologiche, Università di Catania, 95125 Catania, Italy.

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2020 Nov 11; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 11.

Typ publikacji:

Journal Article

MeSH Terms:

Antineoplastic Agents/*chemistry
Butyric Acid/*chemistry
Ferric Compounds/*chemistry
Folic Acid/*chemistry
Magnetite Nanoparticles/*chemistry
Adenocarcinoma/drug therapy ; Adenocarcinoma/metabolism ; Antineoplastic Agents/pharmacology ; Cell Line ; Cell Line, Tumor ; Cell Survival/drug effects ; Colonic Neoplasms/drug therapy ; Colonic Neoplasms/metabolism ; Drug Delivery Systems/methods ; Folate Receptors, GPI-Anchored/metabolism ; Humans ; Magnetics/methods ; Polyethylene Glycols/chemistry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 12.

Tytuł:

Ligand-targeted polymerase chain reaction for the detection of folate receptor-positive circulating tumour cells as a potential diagnostic biomarker for pancreatic cancer.

Autorzy:

Cheng H; Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China.; Department of Hepatobiliary and Pancreatic Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
He W; Department of Medicine, Geno Biotech Co Ltd, Shanghai, China.
Yang J; Department of Pathology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Ye Q; Department of Pathology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Cheng L; Department of Research and Development, Geno Biotech Co Ltd, Shanghai, China.
Pan Y; Department of Hepatobiliary and Pancreatic Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Mao L; Department of Hepatobiliary and Pancreatic Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Chu X; Department of Hepatobiliary and Pancreatic Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Lu C; Department of Hepatobiliary and Pancreatic Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Li G; Department of Hepatobiliary and Pancreatic Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Qiu Y; Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China.; Department of Hepatobiliary and Pancreatic Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
He J; Department of Radiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.

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Źródło:

Cell proliferation [Cell Prolif] 2020 Sep; Vol. 53 (9), pp. e12880. Date of Electronic Publication: 2020 Jul 24.

Typ publikacji:

Journal Article

MeSH Terms:

Folate Receptors, GPI-Anchored/*analysis
Neoplastic Cells, Circulating/*pathology
Pancreatic Neoplasms/*diagnosis
Adult ; Aged ; Aged, 80 and over ; Antigens, Tumor-Associated, Carbohydrate/analysis ; Biomarkers, Tumor/analysis ; Female ; Humans ; Male ; Middle Aged ; Pancreatic Neoplasms/pathology ; Polymerase Chain Reaction

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 13.

Tytuł:

Effect of receptor dimerization on membrane lipid raft structure continuously quantified on single cells by camera based fluorescence correlation spectroscopy.

Autorzy:

Huang H; Department of Physics, University at Buffalo the State University of New York, Buffalo, New York, United States of America.
Simsek MF; Department of Physics, University at Buffalo the State University of New York, Buffalo, New York, United States of America.
Jin W; Department of Physics, University at Buffalo the State University of New York, Buffalo, New York, United States of America.
Pralle A; Department of Physics, University at Buffalo the State University of New York, Buffalo, New York, United States of America; Department of Biophysics and Physiology, University at Buffalo the State University of New York, Buffalo, New York, United States of America.

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Źródło:

PloS one [PLoS One] 2015 Mar 26; Vol. 10 (3), pp. e0121777. Date of Electronic Publication: 2015 Mar 26 (Print Publication: 2015).

Typ publikacji:

Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

MeSH Terms:

Protein Multimerization*
Folate Receptors, GPI-Anchored/*metabolism
Membrane Microdomains/*chemistry
Photography/*instrumentation
Single-Cell Analysis/*instrumentation
Spectrometry, Fluorescence/*instrumentation
Actinin/metabolism ; Cholesterol/metabolism ; Diffusion ; Folate Receptors, GPI-Anchored/chemistry ; Green Fluorescent Proteins/metabolism ; Membrane Proteins/metabolism ; Protein Structure, Tertiary

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 14.

Tytuł:

Mechanisms and implications of dual-acting methotrexate in folate-targeted nanotherapeutic delivery.

Autorzy:

Wong PT; Department of Internal Medicine, Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan Medical School, Ann Arbor, MI 48109, USA. .
Choi SK; Department of Internal Medicine, Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan Medical School, Ann Arbor, MI 48109, USA. .

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2015 Jan 13; Vol. 16 (1), pp. 1772-90. Date of Electronic Publication: 2015 Jan 13.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't; Review

MeSH Terms:

Drug Delivery Systems*
Antimetabolites, Antineoplastic/*administration & dosage
Drug Carriers/*metabolism
Folate Receptors, GPI-Anchored/*metabolism
Folic Acid/*metabolism
Methotrexate/*administration & dosage
Neoplasms/*drug therapy
Animals ; Antimetabolites, Antineoplastic/chemistry ; Dendrimers/chemistry ; Dendrimers/metabolism ; Drug Carriers/chemistry ; Folate Receptors, GPI-Anchored/chemistry ; Folic Acid/chemistry ; Humans ; Methotrexate/chemistry ; Models, Molecular ; Nanoparticles/chemistry ; Nanoparticles/metabolism ; Neoplasms/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 15.

Tytuł:

Pre-clinical studies of EC2629, a highly potent folate- receptor-targeted DNA crosslinking agent.

Autorzy:

Reddy JA; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Nelson M; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Dircksen C; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Vetzel M; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Johnson T; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Cross V; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Westrick E; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Qi L; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Hahn S; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Santhapuram HK; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Parham G; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Wang K; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Vaughn JF; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Felten A; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Pugh M; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Lu J; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Klein P; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Vlahov IR; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA.
Leamon CP; Endocyte, Inc., 3000 Kent Ave., Suite A1-100, West Lafayette, IN, 47906, USA. .

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Źródło:

Scientific reports [Sci Rep] 2020 Jul 29; Vol. 10 (1), pp. 12772. Date of Electronic Publication: 2020 Jul 29.

Typ publikacji:

Journal Article

MeSH Terms:

Antineoplastic Agents/*pharmacology
Cross-Linking Reagents/*pharmacology
DNA/*chemistry
Endometrial Neoplasms/*drug therapy
Folate Receptors, GPI-Anchored/*chemistry
Ovarian Neoplasms/*drug therapy
Triple Negative Breast Neoplasms/*drug therapy
Alkylating Agents/chemistry ; Animals ; Cattle ; Cisplatin/administration & dosage ; Dogs ; Drug Delivery Systems ; Drug Design ; Drug Evaluation, Preclinical ; Female ; Folic Acid/analogs & derivatives ; Folic Acid/pharmacology ; Humans ; Inhibitory Concentration 50 ; KB Cells ; Ligands ; Mice ; Mice, Inbred C57BL ; Mice, Nude ; Paclitaxel/administration & dosage ; Rats ; Vinca Alkaloids/pharmacology ; Xenograft Model Antitumor Assays

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 16.

Tytuł:

Targeted bioimaging and sensing of folate receptor-positive cancer cells using folic acid-conjugated sulfur-doped graphene quantum dots.

Autorzy:

Kadian S; Department of Polymer and Process Engineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India.
Manik G; Department of Polymer and Process Engineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India. .
Das N; Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India.
Roy P; Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India.

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Źródło:

Mikrochimica acta [Mikrochim Acta] 2020 Jul 18; Vol. 187 (8), pp. 458. Date of Electronic Publication: 2020 Jul 18.

Typ publikacji:

Journal Article

MeSH Terms:

Fluorescent Dyes/*chemistry
Folate Receptors, GPI-Anchored/*metabolism
Folic Acid/*metabolism
Graphite/*chemistry
Neoplasms/*diagnostic imaging
Quantum Dots/*chemistry
Fluorescent Dyes/pharmacology ; Folic Acid/chemistry ; Free Radical Scavengers/chemistry ; Free Radical Scavengers/pharmacology ; Graphite/pharmacology ; Humans ; MCF-7 Cells ; Neoplasms/metabolism ; Sulfur/chemistry ; Sulfur/pharmacology

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 17.

Tytuł:

Water-Soluble closo -Docecaborate-Containing Pteroyl Derivatives Targeting Folate Receptor-Positive Tumors for Boron Neutron Capture Therapy.

Autorzy:

Nakagawa F; School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan.
Kawashima H; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan.
Morita T; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan.
Nakamura H; School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan.; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan.

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Źródło:

Cells [Cells] 2020 Jul 03; Vol. 9 (7). Date of Electronic Publication: 2020 Jul 03.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Boron Compounds/*chemistry
Boron Neutron Capture Therapy/*methods
Folate Receptors, GPI-Anchored/*metabolism
Folic Acid/*analogs & derivatives
Nanoconjugates/*chemistry
Neoplasms/*radiotherapy
A549 Cells ; Endocytosis ; HeLa Cells ; Humans ; Neoplasms/metabolism ; Protein Binding

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 18.

Tytuł:

Folic acid receptor-targeted solid lipid nanoparticles to enhance cytotoxicity of letrozole through induction of caspase-3 dependent-apoptosis for breast cancer treatment.

Autorzy:

Yassemi A; Faculty of Chemistry, Razi University, Kermanshah, Iran.
Kashanian S; Faculty of Chemistry, Sensor and Biosensor Research Center (SBRC) & Nanoscience and Nanotechnology Research Center (NNRC), Razi University, Kermanshah, Iran.; Nano Drug Delivery Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Zhaleh H; Substance Abuse Prevention Research Center, Institute of Health, Kermanshah University of medical science, Kermanshah, Iran.

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Źródło:

Pharmaceutical development and technology [Pharm Dev Technol] 2020 Apr; Vol. 25 (4), pp. 397-407. Date of Electronic Publication: 2020 Jan 02.

Typ publikacji:

Journal Article

MeSH Terms:

Antineoplastic Agents/*administration & dosage
Apoptosis/*drug effects
Breast Neoplasms/*drug therapy
Drug Carriers/*metabolism
Folate Receptors, GPI-Anchored/*metabolism
Letrozole/*administration & dosage
Antineoplastic Agents/pharmacology ; Breast Neoplasms/metabolism ; Caspase 3/metabolism ; Drug Delivery Systems ; Female ; Humans ; Letrozole/pharmacology ; Lipid Metabolism ; MCF-7 Cells ; Nanoparticles/metabolism

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 19.

Tytuł:

Co-delivery of Bmi1 small interfering RNA with ursolic acid by folate receptor-targeted cationic liposomes enhances anti-tumor activity of ursolic acid in vitro and in vivo .

Autorzy:

Li W; a Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan , P. R. China.
Yan R; b School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology , Wuhan , P. R. China.
Liu Y; b School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology , Wuhan , P. R. China.
He C; b School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology , Wuhan , P. R. China.
Zhang X; b School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology , Wuhan , P. R. China.
Lu Y; b School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology , Wuhan , P. R. China.
Khan MW; b School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology , Wuhan , P. R. China.
Xu C; b School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology , Wuhan , P. R. China.
Yang T; b School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology , Wuhan , P. R. China.
Xiang G; b School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology , Wuhan , P. R. China.

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Źródło:

Drug delivery [Drug Deliv] 2019 Dec; Vol. 26 (1), pp. 794-802.

Typ publikacji:

Journal Article

MeSH Terms:

Antineoplastic Agents/*administration & dosage
Cations/*chemistry
Folate Receptors, GPI-Anchored/*metabolism
Liposomes/*chemistry
Polycomb Repressive Complex 1/*genetics
Proto-Oncogene Proteins/*genetics
RNA, Small Interfering/*administration & dosage
Triterpenes/*administration & dosage
Animals ; Antineoplastic Agents/chemistry ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Drug Delivery Systems/methods ; Female ; Folic Acid/metabolism ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Neoplastic Stem Cells/drug effects ; RNA, Small Interfering/genetics ; Ursolic Acid

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 20.

Tytuł:

High prevalence of serum folate receptor autoantibodies in children with autism spectrum disorders.

Autorzy:

Zhou J; a Division of Psychology , Shenzhen Children's Hospital , Shenzhen , Guangdong , China.
Liu A; b Shiyan Prevention and Health Care Center of Shenzhen , Shenzhen , Guangdong , China.
He F; c ImunoBio , Shenzhen , Guangdong , China.
Jin Y; d Division of Child Health Care , Xiamen branch, Children's Hospital of Fudan University; Xiamen Children's hospital , Xiamen , Fujian , China.
Zhou S; e Division of Gastroenterology , Shenzhen Children's Hospital , Shenzhen , Guangdong , China.
Xu R; f Clinical Laboratory , Longgang Central Hospital of Shenzhen , Guangdong , China.
Guo H; c ImunoBio , Shenzhen , Guangdong , China.
Zhou W; g Shanghai Key Laboratory of Birth Defects, National Health and Family Planning Commission (NHFPC) Key Laboratory of Neonatal Diseases, Division of Neonatology , Children's Hospital of Fudan University , Shanghai , China.
Wei Q; h Division of Neonatology , Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region , Nanning , China.
Wang M; i Shanghai Key Laboratory of Birth Defects , Xiamen Branch of Children's Hospital of Fudan University (Xiamen Children's Hospital), Children's Hospital of Fudan University , Shanghai , China.

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Źródło:

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals [Biomarkers] 2018 Nov; Vol. 23 (7), pp. 622-624. Date of Electronic Publication: 2018 Sep 06.

Typ publikacji:

Journal Article

MeSH Terms:

Autism Spectrum Disorder/*etiology
Autoantibodies/*blood
Folate Receptors, GPI-Anchored/*immunology
Adolescent ; Case-Control Studies ; Child ; Child, Preschool ; Enzyme-Linked Immunosorbent Assay ; Female ; Folic Acid/metabolism ; Folic Acid/therapeutic use ; Humans ; Male ; Pregnancy ; Prevalence

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 21.

Tytuł:

Folate receptor-targeted mixed polysialic acid micelles for combating rheumatoid arthritis: in vitro and in vivo evaluation.

Autorzy:

Zhang N; a Department of Pharmaceutics , School of Pharmaceutical Sciences, Zhengzhou University , Zhengzhou , HeNan , PR China.; b Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases, HeNan Province , Zhengzhou , HeNan , PR China.; c Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, HeNan Province , Zhengzhou , HeNan , PR China.
Xu C; d Institute of Medical and Pharmaceutical Sciences, Zhengzhou University , Zhengzhou , HeNan , PR China.
Li N; a Department of Pharmaceutics , School of Pharmaceutical Sciences, Zhengzhou University , Zhengzhou , HeNan , PR China.
Zhang S; a Department of Pharmaceutics , School of Pharmaceutical Sciences, Zhengzhou University , Zhengzhou , HeNan , PR China.
Fu L; a Department of Pharmaceutics , School of Pharmaceutical Sciences, Zhengzhou University , Zhengzhou , HeNan , PR China.
Chu X; a Department of Pharmaceutics , School of Pharmaceutical Sciences, Zhengzhou University , Zhengzhou , HeNan , PR China.
Hua H; d Institute of Medical and Pharmaceutical Sciences, Zhengzhou University , Zhengzhou , HeNan , PR China.
Zeng X; e Department of Pharmacy , University of Copenhagen , Copenhagen , Denmark.
Zhao Y; a Department of Pharmaceutics , School of Pharmaceutical Sciences, Zhengzhou University , Zhengzhou , HeNan , PR China.; b Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases, HeNan Province , Zhengzhou , HeNan , PR China.; c Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, HeNan Province , Zhengzhou , HeNan , PR China.

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Źródło:

Drug delivery [Drug Deliv] 2018 Nov; Vol. 25 (1), pp. 1182-1191.

Typ publikacji:

Journal Article

MeSH Terms:

Arthritis, Rheumatoid/*drug therapy
Dexamethasone/*chemistry
Dexamethasone/*pharmacology
Folate Receptors, GPI-Anchored/*metabolism
Sialic Acids/*chemistry
Animals ; Arthritis, Rheumatoid/metabolism ; Biological Availability ; Cell Line ; Dexamethasone/pharmacokinetics ; Drug Carriers/chemistry ; Drug Delivery Systems/methods ; Folic Acid/metabolism ; Interleukin-6/metabolism ; Male ; Mice ; Micelles ; RAW 264.7 Cells ; Rats ; Rats, Sprague-Dawley ; Tissue Distribution ; Tumor Necrosis Factor-alpha/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 22.

Tytuł:

Folate receptor-targeted lipid-albumin nanoparticles (F-LAN) for therapeutic delivery of an Akt1 antisense oligonucleotide.

Autorzy:

Li H; a Division of Pharmaceutics , College of Pharmacy, The Ohio State University , Columbus , OH , USA.
Liu Y; a Division of Pharmaceutics , College of Pharmacy, The Ohio State University , Columbus , OH , USA.
Chen L; a Division of Pharmaceutics , College of Pharmacy, The Ohio State University , Columbus , OH , USA.
Liu Q; a Division of Pharmaceutics , College of Pharmacy, The Ohio State University , Columbus , OH , USA.
Qi S; a Division of Pharmaceutics , College of Pharmacy, The Ohio State University , Columbus , OH , USA.
Cheng X; a Division of Pharmaceutics , College of Pharmacy, The Ohio State University , Columbus , OH , USA.
Lee YB; b Rexahn Pharmaceuticals, Inc. , Rockville , MD , USA.
Ahn CH; b Rexahn Pharmaceuticals, Inc. , Rockville , MD , USA.
Kim DJ; b Rexahn Pharmaceuticals, Inc. , Rockville , MD , USA.
Lee RJ; a Division of Pharmaceutics , College of Pharmacy, The Ohio State University , Columbus , OH , USA.

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Źródło:

Journal of drug targeting [J Drug Target] 2018 Jun - Jul; Vol. 26 (5-6), pp. 466-473. Date of Electronic Publication: 2018 Feb 08.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Nanoparticles*
Carcinoma/*therapy
Oligonucleotides/*administration & dosage
Oligonucleotides, Antisense/*administration & dosage
Proto-Oncogene Proteins c-akt/*antagonists & inhibitors
Albumins/chemistry ; Animals ; Carcinoma/pathology ; Fatty Acids, Monounsaturated/chemistry ; Folate Receptors, GPI-Anchored/metabolism ; Folic Acid/chemistry ; Humans ; KB Cells ; Lipids/chemistry ; Mice ; Mice, Inbred ICR ; Mice, Nude ; Oligonucleotides/pharmacology ; Oligonucleotides, Antisense/pharmacology ; Particle Size ; Phosphatidylethanolamines/chemistry ; Polyethylene Glycols/chemistry ; Quaternary Ammonium Compounds/chemistry ; Vitamin E/chemistry ; Xenograft Model Antitumor Assays

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 23.

Tytuł:

Demonstration of the lack of cytotoxicity of unmodified and folic acid modified graphene oxide quantum dots, and their application to fluorescence lifetime imaging of HaCaT cells.

Autorzy:

Goreham RV; The MacDiarmid Institute for Advanced Materials and Nanotechnology, School of Chemical and Physical Science, Victoria University of Wellington, PO Box 600, Wellington, 6140, New Zealand. .
Schroeder KL; The MacDiarmid Institute for Advanced Materials and Nanotechnology, School of Chemical and Physical Science, Victoria University of Wellington, PO Box 600, Wellington, 6140, New Zealand.
Holmes A; School of Pharmacy and Medical Sciences, The University of South Australia, Adelaide, 5000, Australia.
Bradley SJ; The MacDiarmid Institute for Advanced Materials and Nanotechnology, School of Chemical and Physical Science, Victoria University of Wellington, PO Box 600, Wellington, 6140, New Zealand.
Nann T; The MacDiarmid Institute for Advanced Materials and Nanotechnology, School of Chemical and Physical Science, Victoria University of Wellington, PO Box 600, Wellington, 6140, New Zealand.

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Źródło:

Mikrochimica acta [Mikrochim Acta] 2018 Jan 24; Vol. 185 (2), pp. 128. Date of Electronic Publication: 2018 Jan 24.

Typ publikacji:

Journal Article

MeSH Terms:

Folic Acid/*chemistry
Graphite/*chemistry
Neoplasms/*diagnostic imaging
Optical Imaging/*methods
Quantum Dots/*chemistry
Cell Line, Tumor ; Folate Receptors, GPI-Anchored/analysis ; Folate Receptors, GPI-Anchored/metabolism ; Folic Acid/metabolism ; Humans ; Microscopy, Fluorescence, Multiphoton/methods ; Neoplasms/pathology

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 24.

Tytuł:

Tc-labeled oligomeric nanoparticles as potential agents for folate receptor-positive tumor targeting.

Autorzy:

Liang L; Department of Chemistry, Bengbu Medical College, Bengbu, Anhui, P. R. China.
Zhang X; Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui, China.
Su X; Department of Nuclear Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Li J; Faculty of Pharmacy, Bengbu Medical College, Bengbu, Anhui, P. R. China.
Tian Y; Faculty of Pharmacy, Bengbu Medical College, Bengbu, Anhui, P. R. China.
Xue H; Department of Chemistry, Bengbu Medical College, Bengbu, Anhui, P. R. China.
Xu H; Department of Nuclear Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.

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Źródło:

Journal of labelled compounds & radiopharmaceuticals [J Labelled Comp Radiopharm] 2018 Feb; Vol. 61 (2), pp. 54-60. Date of Electronic Publication: 2018 Feb 22.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Folate Receptors, GPI-Anchored/*metabolism
Folic Acid/*analogs & derivatives
Nanoparticles/*chemistry
Radiopharmaceuticals/*chemical synthesis
Technetium/*chemistry
Hep G2 Cells ; Humans ; Maleimides/chemistry ; Single Photon Emission Computed Tomography Computed Tomography/methods

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 25.

Tytuł:

Synthesis of Luminescent Carbon Dots with Ultrahigh Quantum Yield and Inherent Folate Receptor-Positive Cancer Cell Targetability.

Autorzy:

Liu H; College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450001, China.
Li Z; College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450001, China. .; Institute of Chemical Biology and Nanomedicine, Hunan University, Changsha, 410082, China. .
Sun Y; College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450001, China.
Geng X; College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450001, China.
Hu Y; College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450001, China.
Meng H; College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450001, China.
Ge J; College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450001, China.
Qu L; College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450001, China. .

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Źródło:

Scientific reports [Sci Rep] 2018 Jan 18; Vol. 8 (1), pp. 1086. Date of Electronic Publication: 2018 Jan 18.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Carbon*/chemistry
Quantum Dots*/chemistry
Antineoplastic Agents/*chemical synthesis
Antineoplastic Agents/*pharmacology
Fluorescent Dyes/*chemical synthesis
Fluorescent Dyes/*pharmacology
Folate Receptors, GPI-Anchored/*metabolism
Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Fluorescent Dyes/chemistry ; Folic Acid/chemistry ; Humans ; Nanostructures/chemistry ; Nanostructures/ultrastructure ; Spectroscopy, Fourier Transform Infrared ; X-Ray Diffraction

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 26.

Tytuł:

A cationic conjugated polymer coupled with exonuclease I: application to the fluorometric determination of protein and cell imaging.

Autorzy:

Liu Y; School of Pharmacy, Xinxiang Medical University, Xinxiang, Henan, 453003, People's Republic of China. .
Gao L; Department of toxicology, School of Public Health, Xinxiang Medical University, Xinxiang, Henan, 453003, People's Republic of China.
Yan H; School of Pharmacy, Xinxiang Medical University, Xinxiang, Henan, 453003, People's Republic of China.
Shangguan J; School of Pharmacy, Xinxiang Medical University, Xinxiang, Henan, 453003, People's Republic of China.
Zhang Z; Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan, Hubei, 430000, People's Republic of China.
Xiang X; Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences, Wuhan, Hubei, 430000, People's Republic of China. .

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Źródło:

Mikrochimica acta [Mikrochim Acta] 2018 Jan 16; Vol. 185 (2), pp. 118. Date of Electronic Publication: 2018 Jan 16.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

DNA Repair Enzymes/*chemistry
Exodeoxyribonucleases/*chemistry
Polymers/*chemistry
Proteins/*analysis
Cations ; DNA, Single-Stranded ; Diagnostic Imaging ; Fluorescence ; Fluorescence Resonance Energy Transfer/methods ; Fluorometry ; Folate Receptors, GPI-Anchored ; HeLa Cells ; Humans ; Streptavidin

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 27.

Tytuł:

Folate-receptor-positive circulating tumor cells as an efficacious biomarker for the diagnosis of small pulmonary nodules.

Autorzy:

Xue Y; Department of Thoracic Surgery, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.
Cong W; Department of Thoracic Surgery, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.
Xie S; Department of Thoracic Surgery, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.
Shu J; Department of Thoracic Surgery, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.
Feng G; Department of Thoracic Surgery, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.
Gao H; Department of Thoracic Surgery, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.

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Źródło:

Journal of cancer research and therapeutics [J Cancer Res Ther] 2018; Vol. 14 (7), pp. 1620-1626.

Typ publikacji:

Journal Article

MeSH Terms:

Folate Receptors, GPI-Anchored/*metabolism
Neoplastic Cells, Circulating/*metabolism
Neoplastic Cells, Circulating/*pathology
Solitary Pulmonary Nodule/*blood
Solitary Pulmonary Nodule/*diagnosis
Adult ; Aged ; Biomarkers, Tumor ; Female ; Humans ; Lung Neoplasms/blood ; Lung Neoplasms/diagnosis ; Male ; Middle Aged ; Neoplasm Staging ; ROC Curve ; Tumor Burden

Czasopismo naukowe

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Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 28.

Tytuł:

Enhanced antitumor effect of targeted nanoliposomal bleomycin.

Autorzy:

Chiani M; Pilot Nanobiotechnology Department, Pasteur Institute of Iran, Tehran, Iran.
Azadmanesh K; Virology Department, Pasteur Institute of Iran, Tehran, Iran.
Shokrgozar MA; National Cell Bank of Iran, Pasteur Institute of Iran, Tehran, Iran.
Mehrabi MR; Pilot Nanobiotechnology Department, Pasteur Institute of Iran, Tehran, Iran.
Akbarzadeh A; Pilot Nanobiotechnology Department, Pasteur Institute of Iran, Tehran, Iran.
Norouzian D; Pilot Nanobiotechnology Department, Pasteur Institute of Iran, Tehran, Iran.

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Źródło:

Chemical biology & drug design [Chem Biol Drug Des] 2017 Nov; Vol. 90 (5), pp. 953-961. Date of Electronic Publication: 2017 Jun 15.

Typ publikacji:

Journal Article

MeSH Terms:

Drug Delivery Systems*
Antibiotics, Antineoplastic/*administration & dosage
Bleomycin/*administration & dosage
Neoplasms/*drug therapy
Animals ; Antibiotics, Antineoplastic/pharmacokinetics ; Antibiotics, Antineoplastic/pharmacology ; Antibiotics, Antineoplastic/therapeutic use ; Bleomycin/pharmacokinetics ; Bleomycin/pharmacology ; Bleomycin/therapeutic use ; Carcinoma, Lewis Lung/drug therapy ; Carcinoma, Lewis Lung/metabolism ; Carcinoma, Lewis Lung/pathology ; Cell Line, Tumor ; Female ; Folate Receptors, GPI-Anchored/metabolism ; Humans ; Liposomes ; Mice, Inbred C57BL ; Neoplasms/metabolism ; Neoplasms/pathology

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 29.

Tytuł:

Synthesis of folate‑chitosan nanoparticles loaded with ligustrazine to target folate receptor positive cancer cells.

Autorzy:

Cheng L; Department of Pharmacy, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116027, P.R. China.
Ma H; Department of Pharmacy, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116027, P.R. China.
Shao M; Department of Pharmacy, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116027, P.R. China.
Fan Q; Department of Pharmacy, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116027, P.R. China.
Lv H; Department of Pharmacy, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116027, P.R. China.
Peng J; College of Pharmacy, Dalian Medical University, Dalian, Liaoning 116044, P.R. China.
Hao T; Department of Pharmacy, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116027, P.R. China.
Li D; Department of Pharmacy, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116027, P.R. China.
Zhao C; Department of Pharmacy, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116027, P.R. China.
Zong X; Medical Sciences Program, Indiana University School of Medicine, Bloomington, IN 47408, USA.

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Źródło:

Molecular medicine reports [Mol Med Rep] 2017 Aug; Vol. 16 (2), pp. 1101-1108. Date of Electronic Publication: 2017 Jun 09.

Typ publikacji:

Journal Article

MeSH Terms:

Chitosan/*chemical synthesis
Folate Receptors, GPI-Anchored/*metabolism
Folic Acid/*chemical synthesis
Nanoparticles/*chemistry
Neoplasms/*drug therapy
Pyrazines/*therapeutic use
A549 Cells ; Chitosan/chemistry ; Drug Liberation ; Endocytosis/drug effects ; Folic Acid/chemistry ; Humans ; Hydrogen-Ion Concentration ; MCF-7 Cells ; Nanoparticles/ultrastructure ; Neoplasms/pathology ; Proton Magnetic Resonance Spectroscopy ; Pyrazines/toxicity ; Spectrophotometry, Infrared ; Time Factors

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 30.

Tytuł:

Clinical application of a rapid cervical cancer screening method: Folate receptor-mediated staining of cervical neoplastic epithelia.

Autorzy:

Li D; Department of Obstetrics and Gynecology, the Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, China.
Chen L; Department of Obstetrics & Gynecology, Shaanxi Province People's Hospital, China.
Wang H; Department of Patholgy, the Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, China.
Yang H; Gaoling County Women and Children's Hospital, China.
Dai Y; Department of Obstetrics and Gynecology, the Affiliated Guangren Hospital, School of Medicine, Xi'an Jiaotong University, China.
Yu C; Department of Obstetrics & Gynecology, Shaanxi Province People's Hospital, China.
Dong Y; GY Highland Biotech LLC, New Jersey, USA.

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Źródło:

Asia-Pacific journal of clinical oncology [Asia Pac J Clin Oncol] 2017 Feb; Vol. 13 (1), pp. 44-52. Date of Electronic Publication: 2016 Oct 14.

Typ publikacji:

Journal Article

MeSH Terms:

Coloring Agents/*metabolism
Early Detection of Cancer/*methods
Folate Receptors, GPI-Anchored/*metabolism
Methylene Blue/*metabolism
Uterine Cervical Neoplasms/*diagnosis
Uterine Cervical Dysplasia/*diagnosis
Adult ; Cost-Benefit Analysis ; Female ; Humans ; Middle Aged ; Pregnancy ; Sensitivity and Specificity ; Vaginal Smears/methods

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 31.

Tytuł:

The anti-tumor effect of folate-targeted liposome microbubbles loaded with oridonin as ultrasound-triggered tumor-targeted therapeutic carrier system.

Autorzy:

Wang C; a Department of Pharmaceutical Engineering, Institute of Chemical Engineering , Nanjing University of Science and Technology , Nanjing , PR China.
Li W; a Department of Pharmaceutical Engineering, Institute of Chemical Engineering , Nanjing University of Science and Technology , Nanjing , PR China.
Hu B; a Department of Pharmaceutical Engineering, Institute of Chemical Engineering , Nanjing University of Science and Technology , Nanjing , PR China.

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Źródło:

Journal of drug targeting [J Drug Target] 2017 Jan; Vol. 25 (1), pp. 83-91. Date of Electronic Publication: 2016 Jun 26.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Microbubbles*
Phonophoresis*
Antineoplastic Agents, Phytogenic/*administration & dosage
Diterpenes, Kaurane/*administration & dosage
Drug Carriers/*chemistry
Folic Acid/*chemistry
Animals ; Antineoplastic Agents, Phytogenic/therapeutic use ; Cell Survival/drug effects ; Diterpenes, Kaurane/therapeutic use ; Drug Liberation ; Folate Receptors, GPI-Anchored/metabolism ; Hep G2 Cells ; Humans ; Mice, Inbred BALB C ; Mice, Nude ; Xenograft Model Antitumor Assays

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 32.

Tytuł:

Preparation and performance of a pH-sensitive cisplatin-loaded magnetic nanomedicine that targets tumor cells via folate receptor mediation.

Autorzy:

Chen SJ; Department of Otolaryngology Head and Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China.
Zhang HZ; Department of Otolaryngology Head and Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China.
Wan LC; Department of Otolaryngology Head and Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China.
Jiang SS; Department of Otolaryngology Head and Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China.
Xu YM; Department of Otolaryngology Head and Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China.
Liu F; Department of Otolaryngology Head and Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China.
Zhang T; Department of Otolaryngology Head and Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China.
Ma D; Department of Biomedical Engineering, College of Life Science and Technology, Jinan University, Guangzhou, Guangdong 510632, P.R. China.
Xie MQ; Department of Otolaryngology Head and Neck Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510282, P.R. China.

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Źródło:

Molecular medicine reports [Mol Med Rep] 2016 Jun; Vol. 13 (6), pp. 5059-67. Date of Electronic Publication: 2016 Apr 21.

Typ publikacji:

Journal Article

MeSH Terms:

Drug Delivery Systems*
Hydrogen-Ion Concentration*
Magnetite Nanoparticles*/chemistry
Magnetite Nanoparticles*/ultrastructure
Cisplatin/*administration & dosage
Folate Receptors, GPI-Anchored/*metabolism
Cell Line, Tumor ; Cell Survival/drug effects ; Cisplatin/chemistry ; Dose-Response Relationship, Drug ; Drug Stability ; Folic Acid/analogs & derivatives ; Folic Acid/chemistry ; Humans ; Particle Size ; Polyethylene Glycols/chemistry ; Spectrum Analysis

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 33.

Tytuł:

Delivery of disulfiram into breast cancer cells using folate-receptor-targeted PLGA-PEG nanoparticles: in vitro and in vivo investigations.

Autorzy:

Fasehee H; Tissue Engineering and Biomaterials Research Center, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, 14965/161, Iran.
Dinarvand R; Nanotechnology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Ghavamzadeh A; Hematology, Oncology and Stem cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Science, Tehran, Iran.
Esfandyari-Manesh M; Department of Chemistry, Amirkabir University of Technology, Tehran, Iran.
Moradian H; Tissue Engineering and Biomaterials Research Center, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, 14965/161, Iran.; Faculty of Biomedical Engineering, Amirkabir University of Technology, Tehran, 15875/4413, Iran.
Faghihi S; Tissue Engineering and Biomaterials Research Center, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, 14965/161, Iran. .
Ghaffari SH; Hematology, Oncology and Stem cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Science, Tehran, Iran. .

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Źródło:

Journal of nanobiotechnology [J Nanobiotechnology] 2016 Apr 21; Vol. 14, pp. 32. Date of Electronic Publication: 2016 Apr 21.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Breast Neoplasms/*drug therapy
Disulfiram/*administration & dosage
Folate Receptors, GPI-Anchored/*metabolism
Folic Acid/*analogs & derivatives
Lactic Acid/*administration & dosage
Nanoparticles/*administration & dosage
Polyethylene Glycols/*administration & dosage
Polyglycolic Acid/*administration & dosage
Breast Neoplasms/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Drug Carriers/administration & dosage ; Female ; Folic Acid/administration & dosage ; Folic Acid/metabolism ; Humans ; MCF-7 Cells ; Particle Size ; Polylactic Acid-Polyglycolic Acid Copolymer

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 34.

Tytuł:

Targeted Proteomics Enables Simultaneous Quantification of Folate Receptor Isoforms and Potential Isoform-based Diagnosis in Breast Cancer.

Autorzy:

Yang T; Department of Pharmacy, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, 210029, China.
Xu F; School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China.
Fang D; School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China.
Chen Y; School of Pharmacy, Nanjing Medical University, Nanjing, 211166, China.

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Źródło:

Scientific reports [Sci Rep] 2015 Nov 17; Vol. 5, pp. 16733. Date of Electronic Publication: 2015 Nov 17.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Breast Neoplasms/*diagnosis
Folate Receptors, GPI-Anchored/*metabolism
Adult ; Aged ; Breast/metabolism ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Chromatography, High Pressure Liquid ; Female ; Humans ; Macrophages/metabolism ; Middle Aged ; Peptides/analysis ; Protein Isoforms/metabolism ; Proteomics ; Tandem Mass Spectrometry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 35.

Tytuł:

Multifunctional mitoxantrone-conjugated magnetic nanosystem for targeted therapy of folate receptor-overexpressing malignant cells.

Autorzy:

Barar J; Research Center for Pharmaceutical Nanotechnology, Tabriz, Iran. .; Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. .
Kafil V; Research Center for Pharmaceutical Nanotechnology, Tabriz, Iran. .; Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. .
Majd MH; Research Center for Pharmaceutical Nanotechnology, Tabriz, Iran. dr_mr_.
Barzegari A; Research Center for Pharmaceutical Nanotechnology, Tabriz, Iran. .
Khani S; Research Center for Pharmaceutical Nanotechnology, Tabriz, Iran. .
Johari-Ahar M; Research Center for Pharmaceutical Nanotechnology, Tabriz, Iran. johari_.; Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. johari_.
Asgari D; Research Center for Pharmaceutical Nanotechnology, Tabriz, Iran. .; Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. .
Coukos G; Ludwig Centre for Cancer Research, University of Lausanne, Lausanne, Switzerland. .
Omidi Y; Research Center for Pharmaceutical Nanotechnology, Tabriz, Iran. .; Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. .

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Źródło:

Journal of nanobiotechnology [J Nanobiotechnology] 2015 Mar 26; Vol. 13, pp. 26. Date of Electronic Publication: 2015 Mar 26.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Antineoplastic Agents/*administration & dosage
Folate Receptors, GPI-Anchored/*metabolism
Magnetite Nanoparticles/*administration & dosage
Mitoxantrone/*administration & dosage
Molecular Targeted Therapy/*methods
Antineoplastic Agents/chemistry ; Apoptosis/drug effects ; Apoptosis/genetics ; Cell Line, Tumor/drug effects ; Cell Survival/drug effects ; DNA Fragmentation/drug effects ; Folic Acid/administration & dosage ; Folic Acid/chemistry ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; MCF-7 Cells/drug effects ; Magnetite Nanoparticles/chemistry ; Microscopy, Atomic Force ; Mitoxantrone/chemistry ; Particle Size ; Polyethylene Glycols/chemistry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 36.

Tytuł:

Cancer stratification by molecular imaging.

Autorzy:

Weber J; Heidelberg University Hospital, Department of Nuclear Medicine, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany. .
Haberkorn U; Heidelberg University Hospital, Department of Nuclear Medicine, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany. .
Mier W; Heidelberg University Hospital, Department of Nuclear Medicine, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany. .

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Źródło:

International journal of molecular sciences [Int J Mol Sci] 2015 Mar 04; Vol. 16 (3), pp. 4918-46. Date of Electronic Publication: 2015 Mar 04.

Typ publikacji:

Journal Article; Review

MeSH Terms:

Neoplasms/*diagnostic imaging
Biomarkers, Tumor/metabolism ; Fluorodeoxyglucose F18/chemistry ; Folate Receptors, GPI-Anchored/metabolism ; Humans ; Integrins/metabolism ; Magnetic Resonance Imaging ; Methyltyrosines/chemistry ; Positron-Emission Tomography ; Radiopharmaceuticals/chemistry ; Receptor, ErbB-2/metabolism ; Tomography, X-Ray Computed

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 37.

Tytuł:

Gefitinib loaded folate decorated bovine serum albumin conjugated carboxymethyl-beta-cyclodextrin nanoparticles enhance drug delivery and attenuate autophagy in folate receptor-positive cancer cells.

Autorzy:

Shi Y; College of Pharmacy, Liaoning Medical University, Jinzhou, 121000, P R China. .
Su C; College of Veterinary Medicine, Liaoning Medical University, Jinzhou, 121000, P R China. .
Cui W; National Vaccine & Serum Institute, Beijing, 100024, China. .
Li H; Central Laboratory of Liaoning Medical University, Jinzhou, 121000, P R China. .
Liu L; College of Pharmacy, Liaoning Medical University, Jinzhou, 121000, P R China. .
Feng B; College of Pharmacy, Liaoning Medical University, Jinzhou, 121000, P R China. .
Liu M; College of Pharmacy, Liaoning Medical University, Jinzhou, 121000, P R China. .
Su R; Central Laboratory of Liaoning Medical University, Jinzhou, 121000, P R China. .
Zhao L; College of Pharmacy, Liaoning Medical University, Jinzhou, 121000, P R China. .

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Źródło:

Journal of nanobiotechnology [J Nanobiotechnology] 2014 Oct 30; Vol. 12, pp. 43. Date of Electronic Publication: 2014 Oct 30.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Autophagy/*drug effects
Folic Acid/*chemistry
Nanoparticles/*administration & dosage
Nanoparticles/*chemistry
Quinazolines/*administration & dosage
Adenosine Triphosphate/metabolism ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/chemistry ; Cell Survival/drug effects ; Drug Delivery Systems ; Folate Receptors, GPI-Anchored/metabolism ; Gefitinib ; HeLa Cells/drug effects ; HeLa Cells/metabolism ; Humans ; Molecular Targeted Therapy ; Serum Albumin, Bovine/chemistry ; Spectroscopy, Fourier Transform Infrared ; beta-Cyclodextrins/chemistry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 38.

Tytuł:

The fate of PrP GPI-anchor signal peptide is modulated by P238S pathogenic mutation.

Autorzy:

Guizzunti G; Institut Pasteur, Unité de Trafic Membranaire et Pathogenèse, 25-28 rue du Docteur Roux, 75015, Paris, France.
Zurzolo C

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Źródło:

Traffic (Copenhagen, Denmark) [Traffic] 2014 Jan; Vol. 15 (1), pp. 78-93. Date of Electronic Publication: 2013 Oct 31.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Mutation, Missense*
Protein Sorting Signals*
Prions/*metabolism
Amino Acid Sequence ; Folate Receptors, GPI-Anchored/metabolism ; HeLa Cells ; Humans ; Molecular Sequence Data ; Prions/chemistry ; Prions/genetics ; Proteasome Endopeptidase Complex/metabolism ; Protein Transport ; Proteolysis

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 39.

Tytuł:

Ligand-functionalization of BPEI-coated YVO4:Bi3+,Eu3+ nanophosphors for tumor-cell-targeted imaging applications.

Autorzy:

Chen YC; Department of Applied Chemistry and Institute of Molecular Science, National Chiao Tung University, Science Building 2, 1001 Ta Hsueh Road, Hsinchu, 300 (Taiwan), Fax: (+886) 3-5723764.
Huang SC
Wang YK
Liu YT
Wu TK
Chen TM

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Źródło:

Chemistry, an Asian journal [Chem Asian J] 2013 Nov; Vol. 8 (11), pp. 2652-9. Date of Electronic Publication: 2013 Jul 24.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Ligands*
Bismuth/*chemistry
Europium/*chemistry
Metal Nanoparticles/*chemistry
Oxides/*chemistry
Photosensitizing Agents/*chemistry
Polyethyleneimine/*chemistry
Vanadium/*chemistry
Yttrium/*chemistry
Cell Line, Tumor ; Cell Survival/drug effects ; Epidermal Growth Factor/chemistry ; Epidermal Growth Factor/metabolism ; Folate Receptors, GPI-Anchored/metabolism ; Folic Acid/chemistry ; HeLa Cells ; Humans ; Metal Nanoparticles/toxicity ; Microscopy, Confocal ; Photosensitizing Agents/chemical synthesis ; Photosensitizing Agents/toxicity ; Ultraviolet Rays

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 40.

Tytuł:

Fluorescent magnetic nanoparticles with specific targeting functions for combinded targeting, optical imaging and magnetic resonance imaging.

Autorzy:

Chen YC; a Biomedical Thechnology and Device Research Laboratories, Industrial Technology Research Institute , Hsinchu , 31040 , Taiwan, Republic of China.
Chang WH
Wang SJ
Hsieh WY

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Źródło:

Journal of biomaterials science. Polymer edition [J Biomater Sci Polym Ed] 2012; Vol. 23 (15), pp. 1903-22. Date of Electronic Publication: 2012 May 08.

Typ publikacji:

Evaluation Study; Journal Article

MeSH Terms:

Contrast Media*/chemistry
Ferric Compounds*/chemistry
Fluorescence*
Magnetite Nanoparticles*/chemistry
Animals ; Cell Line, Tumor ; Folate Receptors, GPI-Anchored/metabolism ; Folic Acid/chemistry ; Humans ; Magnetic Resonance Imaging/instrumentation ; Magnetic Resonance Imaging/methods ; Mice, Nude ; Neoplasm Transplantation ; Neoplasms/metabolism ; Neoplasms/pathology ; Optical Imaging/methods ; Particle Size ; Phantoms, Imaging ; Polyethylene Glycols/chemistry ; Silanes/chemistry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 41.

Tytuł:

Folic acid modified gelatine coated quantum dots as potential reagents for in vitro cancer diagnostics.

Autorzy:

Gérard VA; School of Chemistry, Trinity College Dublin, Dublin 2, Ireland.
Maguire CM
Bazou D
Gun'ko YK

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Źródło:

Journal of nanobiotechnology [J Nanobiotechnology] 2011 Nov 10; Vol. 9, pp. 50. Date of Electronic Publication: 2011 Nov 10.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Nanocomposites*/chemistry
Nanocomposites*/toxicity
Quantum Dots*
Folic Acid/*chemistry
Gelatin/*chemistry
Neoplasms/*diagnosis
Caco-2 Cells ; Cadmium Compounds/chemistry ; Folate Receptors, GPI-Anchored/metabolism ; Humans ; Microscopy, Confocal ; Tellurium/chemistry

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 42.

Tytuł:

In vitro and in vivo evaluation of (99m)Tc-DO3A-EA-Folate for receptor-mediated targeting of folate positive tumors.

Autorzy:

Mishra G; Division of Cyclotron and Radiopharmaceuticals, Institute of Nuclear Medicine and Allied Sciences, Brig SK Mazumdar Road, Delhi-110007, India.
Hazari PP
Kumar N
Mishra AK

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Źródło:

Journal of drug targeting [J Drug Target] 2011 Nov; Vol. 19 (9), pp. 761-9. Date of Electronic Publication: 2011 Mar 22.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Organotechnetium Compounds*/chemistry
Organotechnetium Compounds*/pharmacokinetics
Radiopharmaceuticals*/chemistry
Radiopharmaceuticals*/pharmacokinetics
Folate Receptors, GPI-Anchored/*metabolism
Folic Acid/*analogs & derivatives
Neoplasms/*diagnosis
Animals ; Cell Line, Tumor ; Cell Membrane/metabolism ; Female ; Folic Acid/chemistry ; Folic Acid/pharmacokinetics ; Humans ; KB Cells ; Mice ; Mice, Nude ; Neoplasm Transplantation ; Neoplasms/pathology ; Neoplasms, Experimental/diagnosis ; Neoplasms, Experimental/pathology ; Rabbits ; Spectrum Analysis ; Tissue Distribution

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 43.

Tytuł:

Assessment of the roles of ordered lipid microdomains in post-endocytic trafficking of glycosyl-phosphatidylinositol-anchored proteins in mammalian fibroblasts.

Autorzy:

Refaei M; Department of Biochemistry, McGill University, Montréal, Québec, Canada.
Leventis R
Silvius JR

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Źródło:

Traffic (Copenhagen, Denmark) [Traffic] 2011 Aug; Vol. 12 (8), pp. 1012-24. Date of Electronic Publication: 2011 Jun 22.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Endocytosis/*physiology
Fibroblasts/*metabolism
Glycosylphosphatidylinositols/*metabolism
Membrane Microdomains/*metabolism
Animals ; CHO Cells ; Carrier Proteins/metabolism ; Cell Line ; Cell Membrane/metabolism ; Cricetinae ; Cricetulus ; Endosomes/metabolism ; Folate Receptors, GPI-Anchored/metabolism ; Glycosylphosphatidylinositols/chemistry ; Lysosomes/metabolism ; Membrane Microdomains/chemistry ; Membrane Proteins/chemistry ; Membrane Proteins/metabolism ; Phosphatidylethanolamines/chemistry ; Phosphatidylethanolamines/metabolism ; Polyethylene Glycols/chemistry ; Polyethylene Glycols/metabolism ; Protein Transport ; Receptors, Transferrin/metabolism

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 44.

Tytuł:

Antitumor effect of folate-targeted liposomal doxorubicin in KB tumor-bearing mice after intravenous administration.

Autorzy:

Riviere K; Department of Bioengineering and Therapeutic Sciences, School of Pharmacy, University of California, San Francisco, California, USA.
Huang Z
Jerger K
Macaraeg N
Szoka FC Jr

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Źródło:

Journal of drug targeting [J Drug Target] 2011 Jan; Vol. 19 (1), pp. 14-24. Date of Electronic Publication: 2010 Mar 30.

Typ publikacji:

Comparative Study; Journal Article; Research Support, N.I.H., Extramural

MeSH Terms:

Drug Delivery Systems*
Antibiotics, Antineoplastic/*pharmacology
Doxorubicin/*pharmacology
Folate Receptors, GPI-Anchored/*metabolism
Animals ; Antibiotics, Antineoplastic/administration & dosage ; Antibiotics, Antineoplastic/pharmacokinetics ; Doxorubicin/administration & dosage ; Doxorubicin/pharmacokinetics ; Folic Acid/chemistry ; Humans ; Injections, Intravenous ; KB Cells ; Liposomes ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Phosphatidylethanolamines/chemistry ; Polyethylene Glycols/chemistry ; Tissue Distribution ; Xenograft Model Antitumor Assays

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły

Skocz do pozycji: 45.

Tytuł:

Effect of an immunotoxin to folate receptor beta on bleomycin-induced experimental pulmonary fibrosis.

Autorzy:

Nagai T; Department of Immunology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Tanaka M
Hasui K
Shirahama H
Kitajima S
Yonezawa S
Xu B
Matsuyama T

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Źródło:

Clinical and experimental immunology [Clin Exp Immunol] 2010 Aug; Vol. 161 (2), pp. 348-56. Date of Electronic Publication: 2010 Jun 09.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

ADP Ribose Transferases/*therapeutic use
Bacterial Toxins/*therapeutic use
Bleomycin/*pharmacology
Carrier Proteins/*immunology
Exotoxins/*therapeutic use
Immunotoxins/*therapeutic use
Pulmonary Fibrosis/*chemically induced
Pulmonary Fibrosis/*drug therapy
Receptors, Cell Surface/*immunology
Virulence Factors/*therapeutic use
ADP Ribose Transferases/administration & dosage ; ADP Ribose Transferases/genetics ; ADP Ribose Transferases/pharmacology ; Animals ; Antibodies, Monoclonal/genetics ; Antibodies, Monoclonal/immunology ; Antigens, CD/metabolism ; Antigens, Differentiation, Myelomonocytic/metabolism ; Bacterial Toxins/administration & dosage ; Bacterial Toxins/genetics ; Bacterial Toxins/pharmacology ; Carrier Proteins/metabolism ; Chemokine CCL2/metabolism ; Exotoxins/administration & dosage ; Exotoxins/genetics ; Exotoxins/pharmacology ; Folate Receptors, GPI-Anchored ; Humans ; Hydroxyproline/metabolism ; Idiopathic Pulmonary Fibrosis/pathology ; Immunoglobulin Fragments/genetics ; Immunotoxins/administration & dosage ; Immunotoxins/pharmacology ; Lung/metabolism ; Lung/pathology ; Macrophages/drug effects ; Macrophages/metabolism ; Macrophages/pathology ; Macrophages, Alveolar/drug effects ; Macrophages, Alveolar/metabolism ; Macrophages, Alveolar/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Monocyte Chemoattractant Proteins/metabolism ; Pulmonary Fibrosis/pathology ; Receptors, Cell Surface/metabolism ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/pharmacology ; Recombinant Fusion Proteins/therapeutic use ; Survival Analysis ; Transforming Growth Factor beta1/metabolism ; Treatment Outcome ; Tumor Necrosis Factor-alpha/metabolism ; Virulence Factors/administration & dosage ; Virulence Factors/genetics ; Virulence Factors/pharmacology ; Pseudomonas aeruginosa Exotoxin A

Czasopismo naukowe

• na półce

Pełny tekst  Link otwiera się w nowym oknieSzczegóły

Skocz do pozycji: 46.

Tytuł:

The role of folate receptor alpha (FRalpha) in the response of malignant pleural mesothelioma to pemetrexed-containing chemotherapy.

Autorzy:

Nutt JE; Northern Institute for Cancer Research, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
Razak AR
O'Toole K
Black F
Quinn AE
Calvert AH
Plummer ER
Lunec J

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Źródło:

British journal of cancer [Br J Cancer] 2010 Feb 02; Vol. 102 (3), pp. 553-60. Date of Electronic Publication: 2010 Jan 05.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Carrier Proteins/*physiology
Folic Acid Antagonists/*therapeutic use
Glutamates/*therapeutic use
Guanine/*analogs & derivatives
Mesothelioma/*drug therapy
Pleural Neoplasms/*drug therapy
Receptors, Cell Surface/*physiology
Blotting, Western ; Carrier Proteins/analysis ; Carrier Proteins/genetics ; Cell Line, Tumor ; Folate Receptors, GPI-Anchored ; Guanine/therapeutic use ; Humans ; Immunohistochemistry ; Pemetrexed ; Receptors, Cell Surface/analysis ; Receptors, Cell Surface/genetics ; Reverse Transcriptase Polymerase Chain Reaction

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Skocz do pozycji: 47.

Tytuł:

Synthesis of poly(alpha,beta-[N-(2-hydroxyethyl)-L-aspartamide])-folate for drug delivery.

Autorzy:

Zou T; Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Wuhan University, Wuhan 430072, People's Republic of China.
Li SL
Cheng SX
Zhang XZ
Zhuo RX

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Źródło:

Journal of biomaterials science. Polymer edition [J Biomater Sci Polym Ed] 2010; Vol. 21 (6-7), pp. 759-70.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Drug Carriers/*chemical synthesis
Folic Acid/*analogs & derivatives
Nanoparticles/*chemistry
Pharmaceutical Preparations/*administration & dosage
Proteins/*chemical synthesis
Carrier Proteins/metabolism ; Cell Line ; Drug Carriers/chemistry ; Folate Receptors, GPI-Anchored ; Folic Acid/chemical synthesis ; Folic Acid/chemistry ; Folic Acid/pharmacokinetics ; Humans ; Molecular Structure ; Nanoparticles/ultrastructure ; Nuclear Magnetic Resonance, Biomolecular ; Proteins/chemistry ; Proteins/pharmacokinetics ; Receptors, Cell Surface/metabolism ; Spectroscopy, Fourier Transform Infrared

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Skocz do pozycji: 48.

Tytuł:

Maintenance of a constitutive heterochromatin domain in vertebrates by a Dicer-dependent mechanism.

Autorzy:

Giles KE; Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0540, USA.
Ghirlando R
Felsenfeld G

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Źródło:

Nature cell biology [Nat Cell Biol] 2010 Jan; Vol. 12 (1), pp. 94-9; sup pp 1-6. Date of Electronic Publication: 2009 Dec 13.

Typ publikacji:

Journal Article; Research Support, N.I.H., Intramural

MeSH Terms:

Transcription, Genetic*
Carrier Proteins/*genetics
Heterochromatin/*genetics
Histone Deacetylases/*metabolism
Receptors, Cell Surface/*genetics
Ribonuclease III/*metabolism
beta-Globins/*genetics
Acetylation ; Animals ; Cells, Cultured ; Chickens ; Chromatin Immunoprecipitation ; Eukaryotic Initiation Factor-2/genetics ; Eukaryotic Initiation Factor-2/metabolism ; Folate Receptors, GPI-Anchored ; Heterochromatin/metabolism ; Histone Deacetylase Inhibitors/pharmacology ; Histone Deacetylases/genetics ; Histones/metabolism ; Locus Control Region ; RNA Interference ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Ribonuclease III/antagonists & inhibitors ; Ribonuclease III/genetics

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Skocz do pozycji: 49.

Tytuł:

Differential usage of the transport systems for folic acid and methotrexate in normal human T-lymphocytes and leukemic cells.

Autorzy:

Biswal BK; Stem Cell and Molecular Biology Laboratory, Department of Biotechnology, Indian Institute of Technology Madras, Chennai-600036, India.
Verma RS

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Źródło:

Journal of biochemistry [J Biochem] 2009 Nov; Vol. 146 (5), pp. 693-703. Date of Electronic Publication: 2009 Aug 19.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Folic Acid/*metabolism
Leukemia/*metabolism
Leukemia/*pathology
Methotrexate/*metabolism
T-Lymphocytes/*metabolism
Antibodies/pharmacology ; Biological Transport/drug effects ; Buffers ; Carrier Proteins/genetics ; Carrier Proteins/immunology ; Carrier Proteins/metabolism ; Cell Line, Tumor ; Folate Receptors, GPI-Anchored ; Folic Acid/analogs & derivatives ; Gene Expression Regulation/drug effects ; Humans ; Hydrogen-Ion Concentration/drug effects ; Immunohistochemistry ; Ions ; Membrane Transport Proteins/genetics ; Membrane Transport Proteins/metabolism ; Methotrexate/analogs & derivatives ; Mitomycin/pharmacology ; Phosphates/metabolism ; Receptors, Cell Surface/genetics ; Receptors, Cell Surface/immunology ; Receptors, Cell Surface/metabolism ; Reduced Folate Carrier Protein ; Reverse Transcriptase Polymerase Chain Reaction ; Sulfasalazine/pharmacology ; Sulfates/metabolism ; T-Lymphocytes/drug effects ; Time Factors ; Verapamil/pharmacology

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Skocz do pozycji: 50.

Tytuł:

The critical role of alpha-folate receptor in the resistance of melanoma to methotrexate.

Autorzy:

Sánchez-del-Campo L; Department of Biochemistry and Molecular Biology A, School of Biology, University of Murcia, 30100 Murcia, Spain.
Montenegro MF
Cabezas-Herrera J
Rodríguez-López JN

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Źródło:

Pigment cell & melanoma research [Pigment Cell Melanoma Res] 2009 Oct; Vol. 22 (5), pp. 588-600. Date of Electronic Publication: 2009 Jun 02.

Typ publikacji:

Journal Article; Research Support, Non-U.S. Gov't

MeSH Terms:

Drug Resistance, Neoplasm*
Melanoma*/drug therapy
Melanoma*/metabolism
Antimetabolites, Antineoplastic/*therapeutic use
Carrier Proteins/*metabolism
Methotrexate/*therapeutic use
Receptors, Cell Surface/*metabolism
Aged ; Animals ; Antimetabolites, Antineoplastic/chemistry ; Carrier Proteins/genetics ; Cell Line, Tumor ; Endocytosis/physiology ; Folate Receptors, GPI-Anchored ; Folic Acid/chemistry ; Folic Acid/metabolism ; Humans ; Male ; Melanocytes/cytology ; Melanocytes/metabolism ; Melanosomes/metabolism ; Methotrexate/chemistry ; Mice ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Receptors, Cell Surface/genetics

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