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Wyszukujesz frazę ""Perforin"" wg kryterium: Temat


Tytuł:
Involvement of M1-Activated Macrophages and Perforin/Granulysin Expressing Lymphocytes in IgA Vasculitis Nephritis.
Autorzy:
Laskarin G; Department of Physiology, Immunology and Pathophysiology, Faculty of Medicine, University of Rijeka, 51000 Rijeka, Croatia.; Hospital for Medical Rehabilitation of Hearth and Lung Diseases and Rheumatism 'Thalassotherapia-Opatija', 51410 Opatija, Croatia.
Babarovic E; Department of Pathology, Faculty of Medicine, University of Rijeka, 51000 Rijeka, Croatia.
Kifer N; Division of Rheumatology and Immunology, Department of Paediatrics, School of Medicine, University Hospital Centre Zagreb, University of Zagreb, 10000 Zagreb, Croatia.
Bulimbasic S; Department of Pathology and Cytology, School of Medicine, University Hospital Centre Zagreb, University of Zagreb, 10000 Zagreb, Croatia.
Sestan M; Division of Rheumatology and Immunology, Department of Paediatrics, School of Medicine, University Hospital Centre Zagreb, University of Zagreb, 10000 Zagreb, Croatia.
Held M; Division of Rheumatology and Immunology, Department of Paediatrics, School of Medicine, University Hospital Centre Zagreb, University of Zagreb, 10000 Zagreb, Croatia.
Frkovic M; Division of Rheumatology and Immunology, Department of Paediatrics, School of Medicine, University Hospital Centre Zagreb, University of Zagreb, 10000 Zagreb, Croatia.
Gagro A; Children's Hospital Zagreb, Faculty of Medicine, University of Osijek, 31000 Osijek, Croatia.
Coric M; Department of Pathology and Cytology, School of Medicine, University Hospital Centre Zagreb, University of Zagreb, 10000 Zagreb, Croatia.
Jelusic M; Division of Rheumatology and Immunology, Department of Paediatrics, School of Medicine, University Hospital Centre Zagreb, University of Zagreb, 10000 Zagreb, Croatia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 13; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
IgA Vasculitis*/complications
Killer Cells, Natural*/immunology
Macrophages*/immunology
Nephritis*/immunology
Perforin*/metabolism
Antigens, Differentiation, T-Lymphocyte*/metabolism
Macrophage Activation*
Child ; Humans ; Arginase/metabolism ; Adolescent ; Male ; Female
Czasopismo naukowe
Tytuł:
New Insights into Interactions between Mushroom Aegerolysins and Membrane Lipids.
Autorzy:
Popošek LL; Department of Biology, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, 1000 Ljubljana, Slovenia.
Kraševec N; Department of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana, Slovenia.
Bajc G; Department of Biology, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, 1000 Ljubljana, Slovenia.
Glavač U; Department of Biology, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, 1000 Ljubljana, Slovenia.
Hrovatin M; Department of Biology, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, 1000 Ljubljana, Slovenia.
Perko Ž; Department of Biology, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, 1000 Ljubljana, Slovenia.
Slavič A; Department of Biology, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, 1000 Ljubljana, Slovenia.
Pavšič M; Faculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, 1000 Ljubljana, Slovenia.
Sepčić K; Department of Biology, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, 1000 Ljubljana, Slovenia.
Skočaj M; Department of Biology, Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, 1000 Ljubljana, Slovenia.
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Źródło:
Toxins [Toxins (Basel)] 2024 Mar 09; Vol. 16 (3). Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:
Journal Article
MeSH Terms:
Membrane Lipids*
Agaricales*
Fungal Proteins*
Hemolysin Proteins*
Trametes ; Perforin ; Glycerophospholipids ; Phosphatidic Acids
Czasopismo naukowe
Tytuł:
Late Onset of Primary Hemophagocytic Lymphohistiocytosis (HLH) with a Novel Constellation of Compound Heterozygosity Involving Two Missense Variants in the PRF1 Gene.
Autorzy:
Stadermann A; Department of Hematology and Oncology, Bundeswehrkrankemhaus Ulm, Oberer Eselsberg 40, 89081 Ulm, Germany.
Haar M; Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20251 Hamburg, Germany.
Riecke A; Department of Hematology and Oncology, Bundeswehrkrankemhaus Ulm, Oberer Eselsberg 40, 89081 Ulm, Germany.
Mayer T; Department of Hematology and Oncology, Bundeswehrkrankemhaus Ulm, Oberer Eselsberg 40, 89081 Ulm, Germany.
Neumann C; Department of Hematology and Oncology, Bundeswehrkrankemhaus Ulm, Oberer Eselsberg 40, 89081 Ulm, Germany.
Bauer A; Department of Hematology and Oncology, Bundeswehrkrankemhaus Ulm, Oberer Eselsberg 40, 89081 Ulm, Germany.
Schulz A; Department of Pediatric Medicine, University Hospital Ulm, Eythstraße 24, 89075 Ulm, Germany.
Nagarathinam K; Institute of Biochemistry, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.
Gebauer N; Department of Hematology and Oncology, University Hospital Schleswig-Holstein Campus Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.
Böhm S; Institute for Immunodeficiency, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Breisacher Straße 115, 79106 Freiburg, Germany.; Division of Pediatric Stem Cell Transplantation and Immunology, Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.
Groß M; Institute for Immunodeficiency, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Breisacher Straße 115, 79106 Freiburg, Germany.
Grunert M; Department of Nuclear Medicine, Bundeswehrkrankenhaus Ulm, Oberer Eselsberg 40, 89081 Ulm, Germany.; Department of Nuclear Medicine, University Hospital Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany.
Müller M; Department of Hematology and Oncology, Bundeswehrkrankemhaus Ulm, Oberer Eselsberg 40, 89081 Ulm, Germany.
Witte H; Department of Hematology and Oncology, Bundeswehrkrankemhaus Ulm, Oberer Eselsberg 40, 89081 Ulm, Germany.; Department of Hematology and Oncology, University Hospital Schleswig-Holstein Campus Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 27; Vol. 25 (5). Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:
Review; Case Reports
MeSH Terms:
Lymphohistiocytosis, Hemophagocytic*/genetics
Female ; Humans ; Young Adult ; Adult ; Perforin/genetics ; Mutation, Missense ; Exons ; Genomics ; Mutation
Recenzja
Tytuł:
Hyperactivation and enhanced cytotoxicity of reduced CD8 gamma delta T cells in the intestine of patients with Crohn's disease correlates with disease activity.
Autorzy:
Zhu T; Department of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Zhu L; Department of Gastroenterology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Sheng C; Department of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Wu D; Department of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Gu Q; Department of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Jiang Z; Department of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Xu J; Department of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Fu G; Department of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China.
Jiang Y; Department of Pathology, Sir Run Run Shaw Hospital Affiliated with Zhejiang University School of Medicine, Hangzhou, 310000, China. .
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Źródło:
BMC immunology [BMC Immunol] 2024 Feb 09; Vol. 25 (1), pp. 15. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Crohn Disease*
Intraepithelial Lymphocytes*/metabolism
Humans ; Granzymes ; Perforin ; T-Lymphocytes, Cytotoxic ; Intestinal Mucosa ; HLA-DR Antigens ; Receptors, Antigen, T-Cell, gamma-delta/metabolism
Czasopismo naukowe
Tytuł:
Immunohistochemical expression of perforin in adult systemic lupus erythematosus associated macrophage activation syndrome: Clinicohematological correlation and literature review.
Autorzy:
Velayutham B; Department of Pathology with Laboratory Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Padhi S; Department of Pathology with Laboratory Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Devi S; Department of General Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Patra S; Department of Pathology with Laboratory Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Panigrahi C; Department of Pathology with Laboratory Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Ramasubbu MK; Department of Pharmacology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Kumar R; Department of General Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.; Department of General Medicine, All India Institute of Medical Sciences, Deoghar, Jharkhand, India.
Raheman S; Department of Pathology with Laboratory Medicine, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
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Źródło:
Lupus [Lupus] 2024 Jan; Vol. 33 (1), pp. 26-39. Date of Electronic Publication: 2023 Dec 08.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Lupus Erythematosus, Systemic*/complications
Lymphohistiocytosis, Hemophagocytic*
Macrophage Activation Syndrome*/diagnosis
Adult ; Female ; Humans ; Male ; Young Adult ; Fibrinogen ; Perforin
Czasopismo naukowe
Tytuł:
Myeloid-derived suppressor cells inhibit natural killer cells in myelodysplastic syndromes through the TIGIT/CD155 pathway.
Autorzy:
Yue J; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Li J; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Ma J; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Zhai Y; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Shen L; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Zhang W; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Li L; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
Fu R; Department of Hematology, General Hospital of Tianjin Medical University, Tianjin, People's Republic of China.
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Źródło:
Hematology (Amsterdam, Netherlands) [Hematology] 2023 Dec; Vol. 28 (1), pp. 2166333.
Typ publikacji:
Journal Article
MeSH Terms:
Myeloid-Derived Suppressor Cells*/metabolism
Myelodysplastic Syndromes*/metabolism
Humans ; Granzymes/metabolism ; Granzymes/pharmacology ; Perforin/metabolism ; Perforin/pharmacology ; NK Cell Lectin-Like Receptor Subfamily K/metabolism ; Killer Cells, Natural ; Cytokines ; Receptors, Immunologic/metabolism
Czasopismo naukowe
Tytuł:
Mathematical model predicts tumor control patterns induced by fast and slow cytotoxic T lymphocyte killing mechanisms.
Autorzy:
Wang Y; Department of Mathematics, University of Michigan, Ann Arbor, MI, 48109, USA.
Bergman DR; Department of Mathematics, University of Michigan, Ann Arbor, MI, 48109, USA.
Trujillo E; Department of Medicine, Section of Hematology/Oncology, The University of Chicago, Chicago, IL, 60637, USA.
Pearson AT; Department of Medicine, Section of Hematology/Oncology, The University of Chicago, Chicago, IL, 60637, USA.
Sweis RF; Department of Medicine, Section of Hematology/Oncology, The University of Chicago, Chicago, IL, 60637, USA. .
Jackson TL; Department of Mathematics, University of Michigan, Ann Arbor, MI, 48109, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 18; Vol. 13 (1), pp. 22541. Date of Electronic Publication: 2023 Dec 18.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes, Cytotoxic*
Neoplasms*/drug therapy
Humans ; Animals ; Mice ; Immunotherapy/methods ; Perforin ; Models, Theoretical
Czasopismo naukowe
Tytuł:
Circulating cytotoxic immune cell composition, activation status and toxins expression associate with white matter microstructure in bipolar disorder.
Autorzy:
Aggio V; Psychiatry and Clinical Psychobiology Unit, Division of Neurosciences, IRCCS San Raffaele Scientific Institute, San Raffaele Turro, Via Stamira d'Ancona 20, 20127, Milano, Italy. .; Vita-Salute San Raffaele University, Milan, Italy. .
Fabbella L; Clinical Neuroimmunology Unit, Division of Neuroscience, Institute of Experimental Neurology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Poletti S; Psychiatry and Clinical Psychobiology Unit, Division of Neurosciences, IRCCS San Raffaele Scientific Institute, San Raffaele Turro, Via Stamira d'Ancona 20, 20127, Milano, Italy.
Lorenzi C; Psychiatry and Clinical Psychobiology Unit, Division of Neurosciences, IRCCS San Raffaele Scientific Institute, San Raffaele Turro, Via Stamira d'Ancona 20, 20127, Milano, Italy.
Finardi A; Clinical Neuroimmunology Unit, Division of Neuroscience, Institute of Experimental Neurology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Colombo C; Vita-Salute San Raffaele University, Milan, Italy.; Mood Disorders Unit, IRCCS Scientific Institute Ospedale San Raffaele, Milano, Italy.
Zanardi R; Mood Disorders Unit, IRCCS Scientific Institute Ospedale San Raffaele, Milano, Italy.
Furlan R; Vita-Salute San Raffaele University, Milan, Italy.; Clinical Neuroimmunology Unit, Division of Neuroscience, Institute of Experimental Neurology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Benedetti F; Psychiatry and Clinical Psychobiology Unit, Division of Neurosciences, IRCCS San Raffaele Scientific Institute, San Raffaele Turro, Via Stamira d'Ancona 20, 20127, Milano, Italy.; Vita-Salute San Raffaele University, Milan, Italy.
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Źródło:
Scientific reports [Sci Rep] 2023 Dec 14; Vol. 13 (1), pp. 22209. Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:
Journal Article
MeSH Terms:
Bipolar Disorder*
White Matter*/physiology
Humans ; Diffusion Tensor Imaging/methods ; CD8-Positive T-Lymphocytes ; Granzymes ; Perforin ; Anisotropy
Czasopismo naukowe
Tytuł:
Involvement of Innate Immune System in the Pathogenesis of Sepsis-Associated Acute Kidney Injury.
Autorzy:
Uchida T; Department of Nephrology and Blood Purification, Kidney Disease Center, Tokyo Medical University Hachioji Medical Center, Tokyo 193-0998, Japan.
Yamada M; Department of Nephrology and Blood Purification, Kidney Disease Center, Tokyo Medical University Hachioji Medical Center, Tokyo 193-0998, Japan.
Inoue D; Department of Nephrology and Blood Purification, Kidney Disease Center, Tokyo Medical University Hachioji Medical Center, Tokyo 193-0998, Japan.
Kojima T; Department of Nephrology and Blood Purification, Kidney Disease Center, Tokyo Medical University Hachioji Medical Center, Tokyo 193-0998, Japan.
Yoshikawa N; Department of Nephrology and Blood Purification, Kidney Disease Center, Tokyo Medical University Hachioji Medical Center, Tokyo 193-0998, Japan.
Suda S; Division of Critical Care and Emergency Medicine, Tokyo Medical University Hachioji Medical Center, Tokyo 193-0998, Japan.
Kamohara H; Division of Critical Care and Emergency Medicine, Tokyo Medical University Hachioji Medical Center, Tokyo 193-0998, Japan.
Oda T; Department of Nephrology and Blood Purification, Kidney Disease Center, Tokyo Medical University Hachioji Medical Center, Tokyo 193-0998, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 05; Vol. 24 (15). Date of Electronic Publication: 2023 Aug 05.
Typ publikacji:
Journal Article
MeSH Terms:
Sepsis*/complications
Sepsis*/metabolism
Acute Kidney Injury*/metabolism
Humans ; Perforin/metabolism ; Retrospective Studies ; Killer Cells, Natural
Czasopismo naukowe
Tytuł:
Preclinical 3D-model supports an invisibility cloak for adenoid cystic carcinoma.
Autorzy:
Chakraborty R; Applied Biosciences, Faculty of Science and Engineering, Macquarie University, Sydney, NSW, 2109, Australia. .
Darido C; Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, 3000, Australia.
Chien A; School of Natural Sciences, Faculty of Science and Engineering, Macquarie University, Sydney, NSW, 2109, Australia.
Tay A; Applied Biosciences, Faculty of Science and Engineering, Macquarie University, Sydney, NSW, 2109, Australia.
Vickery K; Macquarie Medical School, Faculty of Medicine Health and Human Sciences, Macquarie University, Sydney, NSW, 2109, Australia.
Hu H; Macquarie Medical School, Faculty of Medicine Health and Human Sciences, Macquarie University, Sydney, NSW, 2109, Australia.
Liu F; School of Natural Sciences, Faculty of Science and Engineering, Macquarie University, Sydney, NSW, 2109, Australia.
Ranganathan S; Applied Biosciences, Faculty of Science and Engineering, Macquarie University, Sydney, NSW, 2109, Australia.
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 09; Vol. 13 (1), pp. 17033. Date of Electronic Publication: 2023 Oct 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Adenoid Cystic*/pathology
Humans ; Killer Cells, Natural ; T-Lymphocytes, Regulatory ; Jurkat Cells ; Perforin
Czasopismo naukowe

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